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Institution

Katholieke Universiteit Leuven

EducationLeuven, Belgium
About: Katholieke Universiteit Leuven is a education organization based out in Leuven, Belgium. It is known for research contribution in the topics: Population & Transplantation. The organization has 61109 authors who have published 176584 publications receiving 6210872 citations.


Papers
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Journal ArticleDOI
TL;DR: The view that recurrence of Crohn's disease in the neoterminal ileum after curative ileal resection is dependent on faecal stream is strongly supported.

710 citations

Journal ArticleDOI
TL;DR: In this paper, the authors explore heterogeneities in the determinants of innovating firms' decisions to engage in R&D cooperation, differentiating between four types of cooperation partners: competitors, suppliers, customers, and universities and research institutes.

710 citations

Journal ArticleDOI
TL;DR: Metronidazole therapy for 3 months decreases the severity of early recurrence of Crohn's disease in the neoterminal ileum after resection and seems to delay symptomatic recurrence.

709 citations

Journal ArticleDOI
TL;DR: In this paper, the authors sampled the soil horizons of 40 important Belgian soil series, with textures ranging from sand to heavy clay, and measured their moisture retention characteristic (MRC).
Abstract: We sampled the soil horizons of 40 important Belgian soil series, with textures ranging from sand to heavy clay, and measured their moisture retention characteristic (MRC). Of these horizons, the particle-size distribution in nine fractions, the dry bulk density, and the carbon content were determin

709 citations

Journal ArticleDOI
TL;DR: Preliminary results suggest that erythromycin may have therapeutic value in patients with severe diabetic gastroparesis, and shortened the prolonged gastric-emptying times for both liquids and solids to normal.
Abstract: Erythromycin mimics the effect of the gastrointestinal polypeptide motilin on gastrointestinal motility, probably by binding to motilin receptors and acting as a motilin agonist. Erythromycin may thus have clinical application in patients with disturbances of gastroduodenal motility, such as diabetic gastroparesis. To examine this possibility, we studied the effect of erythromycin on gastric emptying in 10 patients with insulin-dependent diabetes mellitus and gastroparesis. We studied the emptying of liquids and solids simultaneously on separate days after the intravenous administration of erythromycin (200 mg) or placebo, using a double-isotope technique and a double-blind, crossover design. Erythromycin shortened the prolonged gastric-emptying times for both liquids and solids to normal. For example, 120 minutes after the ingestion of a solid meal, mean (+/- SE) retention was 63 +/- 9 percent with placebo and 4 +/- 1 percent with erythromycin, as compared with 9 +/- 3 percent in 10 healthy subjects. The corresponding values 120 minutes after the ingestion of a liquid meal were 32 +/- 4, 9 +/- 3, and 4 +/- 1 percent, respectively. Gastric emptying also improved, but to a lesser degree, in the 10 patients after four weeks of treatment with oral erythromycin (250 mg three times a day). These preliminary results suggest that erythromycin may have therapeutic value in patients with severe diabetic gastroparesis.

708 citations


Authors

Showing all 61602 results

NameH-indexPapersCitations
Eugene Braunwald2301711264576
Joseph L. Goldstein207556149527
Rakesh K. Jain2001467177727
Stefan Schreiber1781233138528
Masayuki Yamamoto1711576123028
Jun Wang1661093141621
David R. Jacobs1651262113892
Klaus Müllen1642125140748
Peter Carmeliet164844122918
Hua Zhang1631503116769
William J. Sandborn1621317108564
Elliott M. Antman161716179462
Tobin J. Marks1591621111604
Ian A. Wilson15897198221
Johan Auwerx15865395779
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023307
2022857
202111,007
202010,541
20199,719
20189,532