Kazimierz Wielki University in Bydgoszcz

About: Kazimierz Wielki University in Bydgoszcz is a education organization based out in Bydgoszcz, Poland. It is known for research contribution in the topics: Luminescence & Population. The organization has 1109 authors who have published 2923 publications receiving 19548 citations. The organization is also known as: Casimir the Great University & Uniwersytet Kazimierza Wielkiego w Bydgoszczy.

Causal neuro-immune relationships at patients with chronic pyelonephritis and cholecystitis. Correlations between parameters EEG, HRV and white blood cell count

Abstract: We aim to analyze in bounds KJ Tracey's immunological homunculus conception the relationships between parameters of electroencephalogram (EEG) and heart rate variability (HRV), on the one hand, and the parameters of bhite blood cell count, on the other hand. METHODS In basal conditions in 23 men, patients with chronic pyelonephritis and cholecystitis in remission, recorded EEG ("NeuroCom Standard", KhAI Medica, Ukraine) and HRV ("Cardiolab+VSR", KhAI Medica, Ukraine). In portion of blood counted up white blood cell count. RESULTS Revealed that canonical correlation between constellation EEG and HRV parameters form with blood level of leukocytes 0.92 (p<10-5), with relative content in white blood cell count stubnuclear neutrophiles 0.93 (p<10-5), segmentonucleary neutrophiles 0.89 (p<10-3), eosinophiles 0.87 (p=0.003), lymphocytes 0.77 (p<10-3) and with monocytes 0.75 (p=0.003). CONCLUSION Parameters of white blood cell count significantly modulated by electrical activity some structures of central and autonomic nervous systems.

Aging in Poland

Abstract: With 38 million residents, Poland has the eighth-largest population in Europe. A successful transition from communism to democracy, which began in 1989, has brought several significant changes to the country's economic development, demographic structure, quality of life, and public policies. As in the other European countries, Poland has been facing a rapid increase in the number of older adults. Currently, the population 65 and above is growing more rapidly than the total population and this discrepancy will have important consequences for the country's economy. As the population ages, there will be increased demands to improve Poland's health care and retirement systems. This article aims to provide a brief overview of the demographic trends in Poland as well a look at the country's major institutions of gerontology research. The article also describes key public policies concerning aging and how these may affect the well-being of Poland's older adults.

Tropomyosin isoforms differentially modulate the regulation of actin filament polymerization and depolymerization by cofilins

Abstract: The specific functions of actin filaments located in the contractile and cytoskeletal compartments of muscle cells depend on the stability and dynamic polymerization/depolymerization of filaments. Tropomyosins and cofilins control the length and dynamic rearrangement of the filaments, although the mechanisms regulating actin dynamics are not well understood. In the present study, we used in vitro assays to examine the regulation of two cofilin isoforms, constitutive cofilin-1 and muscle cofilin-2, by the muscle homodimer Tpm1.1, muscle heterodimer Tpm1.1/Tpm2.2, and the cytoskeletal Tpm3.1. Depolymerization from the pointed end induced by the muscle-specific cofilin-2 was inhibited by all tropomyosins, whereas the muscle isoforms were most effective. By contrast, depolymerization by cofilin-1 was inhibited by Tpm3.1 and Tpm1.1, but not by Tpm1.1/Tpm2.2. Polymerization of G-actin was inhibited by cofilin-2, whereas cofilin-1 had no effect. All three tropomyosins switched on the inhibiting activity of cofilin-1; however, Tpm3.1 and Tpm1.1 were much more efficient. Cofilin-2-induced inhibition of polymerization was affected neither by Tpm1.1, nor by Tpm3.1, but partly relieved by Tpm1.1/Tpm2.2. Cofilins removed tropomyosin isoforms from the filament with different efficiencies, which correlated with the cooperativities of cofilin binding to the F-actin/tropomyosin complex. Because neither zero-length, nor long-arm cross-linking between tropomyosin and cofilin isoforms was observed, the effects of tropomyosin isoforms on the activities of cofilins were executed allosterically. The results reveal that isoform-specific interactions with actin filament permit tropomyosins to discriminate between cofilin isoforms and to differentially regulate their activities.

Countermovement depth - a variable which clarifies the relationship between the maximum power output and height of a vertical jump.

Abstract: Purpose The aim of this study was to identify the determinants of peak power achieved during vertical jumps in order to clarify relationship between the height of jump and the ability to exert maximum power. Methods One hundred young (16.8±1.8 years) sportsmen participated in the study (body height 1.861 ± 0.109 m, body weight 80.3 ± 9.2 kg). Each participant performed three jump tests: countermovement jump (CMJ), akimbo countermovement jump (ACMJ), and spike jump (SPJ). A force plate was used to measure ground reaction force and to determine peak power output. The following explanatory variables were included in the model: jump height, body mass, and the lowering of the centre of mass before launch (countermovement depth). A model was created using multiple regression analysis and allometric scaling. Results The model was used to calculate the expected power value for each participant, which correlated strongly with real values. The value of the coefficient of determination R2 equalled 0.89, 0.90 and 0.98, respectively, for the CMJ, ACMJ, and SPJ jumps. The countermovement depth proved to be a variable strongly affecting the maximum power of jump. If the countermovement depth remains constant, the relative peak power is a simple function of jump height. Conclusions The results suggest that the jump height of an individual is an exact indicator of their ability to produce maximum power. The presented model has a potential to be utilized under field condition for estimating the maximum power output of vertical jumps.