Keele University

About: Keele University is a education organization based out in Newcastle-under-Lyme, United Kingdom. It is known for research contribution in the topics: Population & Stars. The organization has 11318 authors who have published 26323 publications receiving 894671 citations. The organization is also known as: Keele University.

Biaryls Made Easy: PEPPSI and the Kumada–Tamao–Corriu Reaction

Abstract: An easily employed, highly versatile Kumada-Tamao-Corriu (KTC) protocol utilizing the PEPPSI (Pyridine, Enhanced, Precatalyst, Preparation, Stabilization and Initiation) precatalysts 1 and 2 is detailed. The ease-of-use of these catalysts and the synthesis of a wide range of hindered biaryls, large coupling partners and drug-like heterocycles, in high yield, makes the PEPPSI-KTC protocol very attractive. The high reactivity of the PEPPSI system allowed a tetra-ortho-substituted heterocycle, 11 to be synthesized at room temperature for the first time using any protocol. The PEPPSI protocols also tolerated the Boc protecting group and phenols required no protection in modified conditions. A relatively large scale (10 g) reaction was also performed with no loss in performance. Furthermore, PEPPSI-IPr, 1, was compared to previously reported highly active phosphine ligands 42, 43, and 44 and was shown to result in significantly better yields under identical conditions. Finally, we demonstrated that the PEPPSI catalyst system is very adept at performing sequential KTC coupling reactions, analogous to multicomponent reactions, which allow complex polyaryl and polyheteroaryl architectures to be produced in one single operation.

Emotion and performance: Prison officers and the presentation of self in prisons

Abstract: This article explores how prison officers manage and perform emotion on a day-to-day basis. Although the performance of emotion is invariably highlighted when things ‘go wrong’ in prison - perhaps particularly during prison disturbances - the emotional life of prisons at an everyday level has received much less attention. Moreover, although the sociology of the prison has acknowledged the impact of prison on the emotional lives of prisoners there has been much less interest in the emotional impact of the prison on its uniformed staff. This article focuses on how prison officers’ emotions are structured and performed on a daily basis. Prisons are emotional places, but like all organizations, they have their own ‘rules’ about the kinds of emotions it is appropriate for prison officers to express (and indeed feel) at work. In consequence, working in prisons demands a performative attitude on the part of staff, an (often significant) engagement in emotion-work and, relatedly, the employment of various emotion-work strategies.