Keele University

About: Keele University is a education organization based out in Newcastle-under-Lyme, United Kingdom. It is known for research contribution in the topics: Population & Stars. The organization has 11318 authors who have published 26323 publications receiving 894671 citations. The organization is also known as: Keele University.

The genomic basis of parasitism in the Strongyloides clade of nematodes

Abstract: Taisei Kikuchi, Mark Viney, Matthew Berriman and colleagues report the genome sequences of six species of nematodes from the Strongyloides clade of nematodes, including human and animal pathogens, facultative parasites and a free-living species. They find that expansions of the astacin and SCP/TAPS gene families are associated with parasitism in these species.

A brief screening tool for knee pain in primary care (KNEST). 2. Results from a survey in the general population aged 50 and over

Abstract: Objective To use a brief screening tool to identify knee pain (all knee pain, non-chronic and chronic knee pain) and associated health-care use in the general population aged 50 yr and over. Methods A cross-sectional survey was mailed to 8995 individuals registered with three general practices in North Staffordshire, UK. The questionnaire included a Knee Pain Screening Tool (KNEST), the Short Form 36 (SF36), demographic questions and, for those who reported knee pain, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results The survey achieved a 77% response. The 12-month period prevalence of all knee pain was 46.8% [95% confidence interval (CI) 45.6%, 48.0%]. Figures for non-chronic knee pain (pain of less than 3 months duration) and chronic knee pain (pain of more than 3 months duration) were 21.5% (95% CI 20.5%, 22.5%) and 25.3% (95% CI 24.3%, 26.4%) respectively. An estimated 6% of the older population had non-chronic but severe knee pain or disability. Thirty-three per cent of all knee pain sufferers had consulted their general practitioner (GP) about their symptom in the last year. This included 34% of those with non-chronic but severe knee pain or disability and 56% of those with chronic and severe knee pain or disability. The use of private treatments or services for knee pain was minimal. A third of those with chronic and severe knee pain or disability had not used any services (including GP) in the last year. Conclusions The KNEST is a simple tool for the identification of individuals with knee pain and their health-care use. Focusing only on chronic knee pain will underestimate the total need and demand for health-care in knee pain sufferers in the general older population, as non-chronic as well as chronic knee pain has a significant impact on people's lives and on their use of primary health-care. The KNEST, when combined with the WOMAC, identifies population groups who have potentially diverse health-care needs and who might benefit from effective health-care. These data can be used alongside evidence on effective treatments by service planners when considering needs for the care of older adults in primary care.

Determining stellar macroturbulence using asteroseismic rotational velocities from Kepler

Abstract: The Rossiter-McLaughlin effect observed for transiting exoplanets often requires prior knowledge of the stellar projected equatorial rotational velocity (v sini). This is usually provided by measuring the broadening of spectral lines, however this method has uncertainties as lines are also broadened by velocity fields in the stellar photosphere known as macroturbulence (vmac). We have estimated accurate v sini values from asteroseismic analyses of main sequence stars observed by Kepler. The rotational frequency splittings of the detected solar-like oscillations of these stars are determined largely by the near-surface rotation. These estimates have been used to infer the vmac values for 28 Kepler stars. Out of this sample, 26 stars were used along with the Sun to obtain a new calibration between vmac, effective temperature and surface gravity. The new calibration is valid for the temperature range 5200 to 6400 K and the gravity range 4.0 to 4.6 dex. A comparison is also provided with previous vmac calibrations. As a result of this work, vmac, and thus v sini, can now be determined with confidence for stars that do not have asteroseismic data available. We present new spectroscopic v sini values for the WASP planet host stars, using high resolution HARPS spectra.