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Institution

Keele University

EducationNewcastle-under-Lyme, United Kingdom
About: Keele University is a education organization based out in Newcastle-under-Lyme, United Kingdom. It is known for research contribution in the topics: Population & Stars. The organization has 11318 authors who have published 26323 publications receiving 894671 citations. The organization is also known as: Keele University.
Topics: Population, Stars, Health care, Galaxy, Planet


Papers
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Journal ArticleDOI
TL;DR: What the authors mean by a population and a sample and the implications of each for survey research are discussed and examples of correct and incorrect sampling techniques used in software engineering surveys are provided.
Abstract: This article is the fifth installment of our series of articles on survey research. In it, we discuss what we mean by a population and a sample and the implications of each for survey research. We provide examples of correct and incorrect sampling techniques used in software engineering surveys.

326 citations

Journal ArticleDOI
15 Jan 1998-Genomics
TL;DR: The molecular cloning, tissue distribution, and chromosomal localization of novel genes encoding G-protein-coupled receptors (GPCRs) are reported, and the gene encoding GPR30 was localized to chromosome 7p22 and GPR35 to chromosome 2q37.

326 citations

Journal ArticleDOI
Robert Ladrech1
TL;DR: The Europeanization is a term used to describe the effects of European integration on the politics and policies of its member states as well as the process of enhancing European-level political institu... as discussed by the authors.
Abstract: Europeanization is a term used to describe the effects of European integration on the politics and policies of its member states as well as the process of enhancing European-level political institu...

326 citations

Journal Article
Christian D Mallen1, George Peat1, Elaine Thomas1, Kate M. Dunn1, Peter Croft1 
TL;DR: Potential generic prognostic indicators that may be useful when assessing any regional musculoskeletal pain complaint are identified, however, it is unclear whether these indicators, used alone, or in combination, can correctly estimate the likely course of individual patients' problems.
Abstract: Background Estimating the future course of musculoskeletal pain is an important consideration in the primary care consultation for patients and healthcare professionals. Studies of prognostic indicators tend to have been viewed in relation to each site separately, however, an alternative view is that some prognostic indicators may be common across different sites of musculoskeletal pain. Aim To identify generic prognostic indicators for patients with musculoskeletal pain in primary care. Design of study Systematic review. Setting Observational cohort studies in primary care. Method MEDLINE, EMBASE, PsychINFO and CINAHL electronic databases were searched from inception to April 2006. Inclusion criteria were that the study was a primary care-based cohort, published in English and contained information on prognostic indicators for musculoskeletal conditions. Results Forty-five studies were included. Eleven factors, assessed at baseline, were found to be associated with poor outcome at follow up for at least two different regional pain complaints: higher pain severity at baseline, longer pain duration, multiple-site pain, previous pain episodes, anxiety and/or depression, higher somatic perceptions and/or distress, adverse coping strategies, low social support, older age, higher baseline disability, and greater movement restriction. Conclusion Despite substantial heterogeneity in the design and analysis of original studies, this review has identified potential generic prognostic indicators that may be useful when assessing any regional musculoskeletal pain complaint. However, Its unclear whether these indicators, used alone, or in combination, can correctly estimate the likely course of individual patients9 problems. Further research is needed, particularly in peripheral joint pain and using assessment methods feasible for routine practice.

325 citations

Journal ArticleDOI
TL;DR: Ten key recommendations for diagnosis of hand OA were developed using research evidence and expert consensus based on assessment of a composite of features, finding that no single test could be used to define hand Oa on its own but a Composite of tests greatly increased the chance of the diagnosis.
Abstract: Objectives: To develop evidence-based recommendations for the diagnosis of hand osteoarthritis (OA). Methods: The multidisciplinary guideline development group, representing 15 European countries, generated 10 key propositions regarding diagnosis using a Delphi consensus approach. For each recommendation, research evidence was searched for systematically. Whenever possible, the sensitivity, specificity and likelihood ratio (LR) were calculated; relative risk and odds ratios were estimated for risk factors for hand OA. Quality of evidence was categorised using the European League Against Rheumatism (EULAR) hierarchy, and strength of recommendation was assessed by the EULAR visual analogue scale. Results: Diagnostic topics included clinical manifestations, radiographic features, subgroups, differential diagnosis, laboratory tests, risk factors and comorbidities. The sensitivity, specificity and LR varied between tests depending upon the cut-off level, gold standard and controls. Overall, no single test could be used to define hand OA on its own (LR ,10) but a composite of the tests greatly increased the chance of the diagnosis. The probability of a subject having hand OA was 20% when Heberden nodes alone were present, but this increased to 88% when in addition the subject was over 40 years old, had a family history of nodes and had joint space narrowing in any finger joint. Conclusion: Ten key recommendations for diagnosis of hand OA were developed using research evidence and expert consensus. Diagnosis of hand OA should be based on assessment of a composite of features.

324 citations


Authors

Showing all 11402 results

NameH-indexPapersCitations
George Davey Smith2242540248373
Simon D. M. White189795231645
James F. Wilson146677101883
Stephen O'Rahilly13852075686
Wendy Taylor131125289457
Nicola Maffulli115157059548
Georg Kresse111430244729
Patrick B. Hall11147068383
Peter T. Katzmarzyk11061856484
John F. Dovidio10946646982
Elizabeth H. Blackburn10834450726
Mary L. Phillips10542239995
Garry P. Nolan10447446025
Wayne W. Hancock10350535694
Mohamed H. Sayegh10348538540
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202344
2022155
20211,473
20201,377
20191,178
20181,106