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Institution

Kettering University

EducationFlint, Michigan, United States
About: Kettering University is a education organization based out in Flint, Michigan, United States. It is known for research contribution in the topics: Cancer & RNA. The organization has 6842 authors who have published 7689 publications receiving 337503 citations. The organization is also known as: GMI Engineering & Management Institute & General Motors Institute.
Topics: Cancer, RNA, Antigen, DNA, Population


Papers
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Journal ArticleDOI
TL;DR: The metabolism of endogenously produced and exogenous tracer doses of labeled hydrocortisone was studied in euthyroid subjects, in spontaneous hyperthyroidism, in myxedema, and following administration of triiodothyronine.
Abstract: The metabolism of endogenously produced and exogenous tracer doses of labeled hydrocortisone was studied in euthyroid subjects, in spontaneous hyperthyroidism, in myxedema, and following administration of triiodothyronine. It was found that an elevated level of thyroid hormone caused pronounced alteration in the metabolism of hydrocortisone toward 11-ketonic metabolites, together with an absolute increase in the endogenous production of the adrenal hormone. In hypothyroidism the converse of these effects was found, in that the metabolism of hydrocortisone was shifted toward the production of 11-hydroxy metabolites together with a decreased formation of hydrocortisone from endogenous sources. A mechanism is suggested for these changes in the production and metabolism of hydrocortisone.

131 citations

Journal ArticleDOI
TL;DR: This work investigates how capping and methylation of HIV pre-mRNAs are coupled to Pol II elongation and implicates capping in an elongation checkpoint critical to HIV gene expression.

131 citations

Journal ArticleDOI
TL;DR: It is concluded that, although most patients with type 1 neurofibromatosis and gastrointestinal stromal tumors do not have KIT or PDGFRA mutations, KIT germline mutations might be implicated in the pathogenesis of gastrointestinal stromaal tumors in some patients.

131 citations

Journal ArticleDOI
01 Jun 1979-Cell
TL;DR: Qualitative and quantitative estimates indicate that p63/6.9 is one of the most prominent proteins on the testicular cell surface, relative to other detergent-soluble testicularcell proteins known to be internal.

130 citations

Proceedings ArticleDOI
19 May 2002
TL;DR: In this article, the Schatz Energy Research Center (SERC) installed a PV array comprised of 192 ARCO M-75 modules, which were tested in order to re-evaluate their performance.
Abstract: In 1990 the Schatz Energy Research Center (SERC) installed a PV array comprised of 192 ARCO M-75 modules. Prior to installation, Zoellick carefully measured module performance and reported average peak power at normal operating cell temperature (NOCT) to be 39.88 W, which was 14.1% lower than the 46.4 W nameplate rating. For the past 11 years the array has been exposed to and employed in a cool, marine environment. Of the original 192 modules, 191 were tested in order to re-evaluate their performance. This paper describes the equipment, conditions, and procedure used in retesting the modules, and reports module performance results. Notable results are that average module short circuit current and maximum power production at NOCT have decreased by 6.38% and 4.39%, respectively.

130 citations


Authors

Showing all 6853 results

NameH-indexPapersCitations
Joan Massagué189408149951
Chris Sander178713233287
Timothy A. Springer167669122421
Murray F. Brennan16192597087
Charles M. Rice15456183812
Lloyd J. Old152775101377
Howard I. Scher151944101737
Paul Tempst14830989225
Pier Paolo Pandolfi14652988334
Barton F. Haynes14491179014
Jedd D. Wolchok140713123336
James P. Allison13748383336
Harold E. Varmus13749676320
Scott W. Lowe13439689376
David S. Klimstra13356461682
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20238
202216
2021211
2020234
2019204
2018225