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Institution

Kettering University

EducationFlint, Michigan, United States
About: Kettering University is a education organization based out in Flint, Michigan, United States. It is known for research contribution in the topics: RNA & Antigen. The organization has 6842 authors who have published 7689 publications receiving 337503 citations. The organization is also known as: GMI Engineering & Management Institute & General Motors Institute.
Topics: RNA, Antigen, DNA, Cancer, Population


Papers
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Journal ArticleDOI
24 Oct 1970-Nature
TL;DR: These findings stimulated a study of the possible universal appearance of embryonic antigens in cancer tissues, which has been detected in colonic, hepatic and lung cancers.
Abstract: VARIOUS reports of embryonal antigens in extracts of tumour tissues have appeared since 1932 (refs. 1–9). Such antigens, absent from homologous normal tissues, have been detected in colonic6, hepatic7 and lung cancers8. These findings stimulated a study of the possible universal appearance of embryonic antigens in cancer tissues.

124 citations

Journal ArticleDOI
TL;DR: Thermolysis of isonitriles with carboxylic acids provides, in one step, N-formyl imides, which allows for a new route for synthesizing beta-N (asparagine)-linked glycosyl amino acids.
Abstract: Thermolysis of isonitriles with carboxylic acids provides, in one step, N-formyl imides (see, for example, 8 + 19 → 21). The resultant N-formyl group can be converted to N−H, NCH2OH, or NCH3. This chemistry allows for a new route for synthesizing β-N (asparagine)-linked glycosyl amino acids.

124 citations

Journal ArticleDOI
TL;DR: It is shown that specificity for polyUbLys48 chains is predicated on contacts in the S2 site and enhanced by an S1-S1′ preference for a Lys48 linkage across the active site, which should prove useful in understanding PLpro deubiquitinating activities in coronavirus infections.

124 citations

Journal ArticleDOI
19 Sep 2003-Cell
TL;DR: It is demonstrated that proteoglycans are required during mouse gastrulation specifically to promote Fgf signaling, and signaling by the growth factors Nodal and Wnt3 appears to be normal in lzme embryos.

123 citations


Authors

Showing all 6853 results

NameH-indexPapersCitations
Joan Massagué189408149951
Chris Sander178713233287
Timothy A. Springer167669122421
Murray F. Brennan16192597087
Charles M. Rice15456183812
Lloyd J. Old152775101377
Howard I. Scher151944101737
Paul Tempst14830989225
Pier Paolo Pandolfi14652988334
Barton F. Haynes14491179014
Jedd D. Wolchok140713123336
James P. Allison13748383336
Harold E. Varmus13749676320
Scott W. Lowe13439689376
David S. Klimstra13356461682
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20238
202216
2021211
2020234
2019204
2018225