Institution
Kettering University
Education•Flint, Michigan, United States•
About: Kettering University is a education organization based out in Flint, Michigan, United States. It is known for research contribution in the topics: RNA & Antigen. The organization has 6842 authors who have published 7689 publications receiving 337503 citations. The organization is also known as: GMI Engineering & Management Institute & General Motors Institute.
Topics: RNA, Antigen, DNA, Cancer, Population
Papers published on a yearly basis
Papers
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TL;DR: These findings stimulated a study of the possible universal appearance of embryonic antigens in cancer tissues, which has been detected in colonic, hepatic and lung cancers.
Abstract: VARIOUS reports of embryonal antigens in extracts of tumour tissues have appeared since 1932 (refs. 1–9). Such antigens, absent from homologous normal tissues, have been detected in colonic6, hepatic7 and lung cancers8. These findings stimulated a study of the possible universal appearance of embryonic antigens in cancer tissues.
124 citations
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124 citations
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TL;DR: Thermolysis of isonitriles with carboxylic acids provides, in one step, N-formyl imides, which allows for a new route for synthesizing beta-N (asparagine)-linked glycosyl amino acids.
Abstract: Thermolysis of isonitriles with carboxylic acids provides, in one step, N-formyl imides (see, for example, 8 + 19 → 21). The resultant N-formyl group can be converted to N−H, NCH2OH, or NCH3. This chemistry allows for a new route for synthesizing β-N (asparagine)-linked glycosyl amino acids.
124 citations
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TL;DR: It is shown that specificity for polyUbLys48 chains is predicated on contacts in the S2 site and enhanced by an S1-S1′ preference for a Lys48 linkage across the active site, which should prove useful in understanding PLpro deubiquitinating activities in coronavirus infections.
124 citations
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TL;DR: It is demonstrated that proteoglycans are required during mouse gastrulation specifically to promote Fgf signaling, and signaling by the growth factors Nodal and Wnt3 appears to be normal in lzme embryos.
123 citations
Authors
Showing all 6853 results
Name | H-index | Papers | Citations |
---|---|---|---|
Joan Massagué | 189 | 408 | 149951 |
Chris Sander | 178 | 713 | 233287 |
Timothy A. Springer | 167 | 669 | 122421 |
Murray F. Brennan | 161 | 925 | 97087 |
Charles M. Rice | 154 | 561 | 83812 |
Lloyd J. Old | 152 | 775 | 101377 |
Howard I. Scher | 151 | 944 | 101737 |
Paul Tempst | 148 | 309 | 89225 |
Pier Paolo Pandolfi | 146 | 529 | 88334 |
Barton F. Haynes | 144 | 911 | 79014 |
Jedd D. Wolchok | 140 | 713 | 123336 |
James P. Allison | 137 | 483 | 83336 |
Harold E. Varmus | 137 | 496 | 76320 |
Scott W. Lowe | 134 | 396 | 89376 |
David S. Klimstra | 133 | 564 | 61682 |