Khulna Medical College

About: Khulna Medical College is a healthcare organization based out in Khulna, Bangladesh. It is known for research contribution in the topics: Pregnancy & Hysterectomy. The organization has 266 authors who have published 203 publications receiving 964 citations. The organization is also known as: Khulna Medical College, Khulna & KMC.

Incidence of Congenital Hypothyroidism in the Newborn of A Tertiary Hospital in Southern Bangladesh

Abstract: Background: Congenital hypothyroidism is the commonest preventable cause of mental retardation. It is more prevalent in endemic goiter regions like Bangladesh. But magnitude of the problem has not been studied at national level. Objective: To detect the incidence of congenital hypothyroidism among the newborn delivered in Khulna Medical College Hospital in southern part of Bangladesh and to rationalize the development of neonatal screening program. Methodology: All the living newborns delivered between Oct '01 to June ‘05 in Khulna Medical College Hospital were included in the study. After taking the relevant information from mother, cord blood sample were collected from the newborn within 24 hours of birth and kept in freezer. At the end of collection of each two month, the lot of blood sample was sent to the laboratory of Institute of Nuclear Medicine, Dhaka for radioimmunoassay of TSH. Potential cases with TSH value above 10 MIU/L were recalled for thyroid function test for confirmation of diagnosis. Results: After discarding unsatisfactory samples, 1353 samples were assayed for TSH. Among the study population 88.2% hailed from Khulna district and the rest of the cases came from neighboring districts. Male to female ratio was 1.2:1. Regarding the birth weight 33.4% babies were of low birth weight. TSH above 10 MIU/L were found in 35 babies among whom one baby was hypothyroid and the other member of the twin was also hypothyroid although the TSH level was below 10 MIU/L. Thus incidence of congenital hypothyroidism was 1.5 per thousand living newborn among the studied cases. Conclusion: The incidence of congenital hypothyroidism in southern part of the country is quite high in relation to global incidence. Although this is not the national picture but the high figure is alarming. So, neonatal screening program should be implemented as soon as possible to find out the real case burden in the community and thereby to take care of them and reduce the number of mentally retarded children in our country. Key words: Congenital hypothyroidism; neonatal screening; mental retardation. DOI: 10.3329/bjch.v29i3.6186 Bangladesh J Child Health 2005; Vol 29 (3): 88-92

Functional endoscopic sinus surgery for the management of sinonasal diseases

Abstract: This study was carried out to observe the role and outcome of endoscopic sinus surgery in the management of sinonasal disease. Study was done in department of ENT & Head-Neck Surgery, Dhaka Medical College, Dhaka from July 2002 to June 2004 (2 years). Sixty patients (60) were included retrospectively for this work. Main presenting symptoms of patients were nasal obstruction (78.33%), nasal discharge (73.33%), headache (51.66%) and recurrent sore throat (50%). In this series, minor complications occurred in 13.3% which includes synechiae, haemorrhage, infection and eccymosis of eye. No major complications like CSF leak, retroorbital haemorrhage, blindness were noted. Only 3 cases (5%) had severe haemorrohage. Most of the patients have got complete symptomatic relief, 5 cases had no improvement. It was concluded that functional endoscopic sinus surgery (FESS) has provided a safe and efficient method for dealing with different sinonasal disease and can be performed with high success rate for alleviation of symptoms with negligible morbidity.

Acute pancreatitis- a clinical update

Abstract: Acute pancreatitis is an acute inflammatory process of the pancreas that can range from mild interstitial pancreatitis to severe pancreatitis with pancreatic necrosis with variable involvement of regional tissues and remote organ systems. The incidence of pancreatitis varies in different countries and depends on causes e.g, gallstones, alcohol, metabolic factors and viral infections. Gall stones continue to be the leading cause of acute pancreatitis in most series. Alcohol, hypertriglyceridemia and drugs are also a common cause of acute pancreatitis. Gall stone pancreatitis is more common in women than in men. Alcohol is also a common cause of acute pancreatitis. Alcoholic pancreatitis is more common in men, and usually occurs in individuals with long standing alcohol abuse. The increased frequency of acute pancreatitis may be due to the rising incidence of obesity, a risk factor for the development of gallstones and by extension, gallstone pancreatitis. Acute pancreatitis occurs when there is abnormal activation of digestive enzymes within the pancreas. This occurs through inappropriate activation of inactive enzyme precursors called zymogens or proenzymes inside the pancreas, most notably trypsinogen. Acute pancreatitis is typically rapid in onset and most commonly encountered in its mild form. While mild cases are often successfully treated with conservative measures, such as fasting and aggressive intravenous fluid rehydration, severe cases may require admission to the intensive care unit or even surgery to deal with complications of the disease process. Acute pancreatitis may be accompanied by life threatening complications as well as significant morbidity and mortality despite treatment. Bang Med J (Khulna) 2017; 50 : 35-40

Prevalence of Hepatitis B Virus and Hepatitis C Virus in a Tea Garden of Bangladesh.

Abstract: Introduction The overall health status of workers of tea garden of Bangladesh is below the national standard. Also, almost nothing has been reported about status of hepatitis virus infection among these population and there is also a lack of consensus. Materials and methods Several health-related facts, especially those of liver diseases, were collected from 130 workers of tea garden via questionnaire. Sera were also collected from these subjects to assess positivity of hepatitis B surface antigen (HBsAg) and antibody to hepatitis C virus (anti-HCV). Hepatitis B virus (HBV) genotype was also done using genotype-specific primers in HBsAg-positive sera. Results Out of 130 tea garden workers, 5 were positive for HBsAg; however, none was reactive to anti-HCV. Genotyping of HBV deoxyribonucleic acid of 4 sera samples revealed that 2 belonged to genotype A, 1 to genotype C, and 1 to genotype D. Various risk factors were documented in HBV-infected subjects by analyzing the questionnaire. Conclusion Hepatitis B virus in considerable high percentage is prevalent among workers of tea garden in Bangladesh, and immediate vaccination against HBV should be employed. Also, health education system should be accentuated in specific population like tea garden workers.How to cite this article: Al Mahtab M, Akhter S, Mollick KU, Uddin MH, Khan SI, Akbar SMF. Prevalence of Hepatitis B Virus and Hepatitis C Virus in a Tea Garden of Bangladesh. Euroasian J Hepato-Gastroenterol 2017;7(1):107-110.