Khulna Medical College

About: Khulna Medical College is a healthcare organization based out in Khulna, Bangladesh. It is known for research contribution in the topics: Pregnancy & Hysterectomy. The organization has 266 authors who have published 203 publications receiving 964 citations. The organization is also known as: Khulna Medical College, Khulna & KMC.

Randomized controlled trial of three oxytocic regimens to prevent primary postpartum haemorrhage at caesarean section

Abstract: The objective of this present study was to compare the efficacy of three oxytocic regimens to prevent primary postpartum haemorrhage (PPH) at caesarean section. A randomized controlled trial including 90 patients who underwent caesarean section were selected according to inclusion and exclusion criteria assigned randomly into three groups (30 patients in each group) was conducted. Group 1 and group 2 were exposure groups and group 3 was control group. All patients were given 10 units intravenous (IV) bolus oxytocin immediately after delivery of baby. Group 1 was given additional 20 units oxytocin in each 1000 ml fluid for 24 hours. Group 2 received additional 1000 microgram misoprostol per rectal. Group 3 did not receive any additional oxytocic drug. Background characteristics of all the three groups were similar. It was observed that 501-1000 ml blood loss was found among 25 (83.3%) cases in group 1, 27 (90.0%) in group 2 and 27 (90.0%) in group 3. The mean (SD) amount of blood loss was found 733 (190) ml in group 1792 (187) ml in group 2 and 818 (14) ml in group 3. Occurrence of PPH and blood transfusion needed among 1 (3.3%) in group 1, 2 (6.7%) in group 2 and 3 (10.0%) in group 3. Side effects occurred in 7 (23.3%) patients of group 1, 18 (60.0%) in group 2, and 6 (20.0%) in group 3. Shivering was found among 4 (13.3%) in group 1, 10 (33.3%) in group 2 and 3 (10%) in group 3. Vomiting was found among 2 (6.7%) in group 1, 4 (13.3%) in group 2, and 2 (6.7%) in group 3. Pyrexia was 1 (3.3%) in group 1, 4 (13.3%) in group 2 and 1 (3.3%) in group 3. Side effects were more in the group where misoprostol was used. Except side effects there was no statistical difference of occurrence of different events among the three groups. Only bolus IV oxytocin appears to be as effective as oxytocin infusion in addition to bolus IV oxytocin or per rectal misoprostol in addition to bolus IV oxytocin to prevent primary PPH at caesarean section. But occurrence of transient side effects such as shivering, pyrexia and vomiting were noted more frequently with the use of misoprostol. Mediscope Vol. 4, No. 2: Jul 2017, Page 5-11

Anthropometry of the nose: a comparative study between adult male Santhals and Bengalis in Bangladesh

Abstract: Anthropometry is a scientific methods for taking various measurements of body parts and observation on the living subjects, which play an important role in distinguishing a pure race. The nose is a person's most defining feature because it is at the center of the face. The shape of the nose is a signature indicating the ethnicity, race, age and sex. The aim of this study is to document the mean nasal length, nasal width and nasal index of adult male Santhals and Bengalis in Bangladesh, which provides a comprehensive data for comparisons between each other and with the other ethnic group. Santhals, our study subjects living in the northwest part of Bangladesh, are usually recognized as an ethnic community. Because the Santhals have separate identity and their physical appearance is distinctive to some extent. The study, descriptive, observational and cross sectional is nature, was carried out in the Department of Anatomy, Rangpur Medical College, Rangpur, during the season of July, 2011 to June, 2012. A total number of 100 adult male Santhals and 100 adult male Bengalis were included from different location of Rangur and Dinajpur districts. Nasal length and nasal width were measured using sliding caliper and nasal index was calculated. Unpaired t -test was used to compare the measurement. The mean nose length of the Bengalis were significantly higher than the Santhals but the mean of nose width were significantly higher in Santhals than Bengalis. Most of the Santhals were mesorrhine, but most of the Bengalis were leptorrhine. Mediscope Vol. 2, No. 2: July 2015, Pages 28-32

The MURCS Association: Mullerian Duct Aplasia, Renal Hypoplasia and Cervicothoracic Somite Dysplasia - A Case Report.

Abstract: We report on a 22 years old lady with aplasia of uterus and most of the vagina with normal secondary sexual characteristics, unilateral renal hypoplasia and anomalies of cervico throacic somites (MURCS Association), growth retardation, cardiac defect and congenital urethrovaginal fistula. Although there is a broad spectrum of anomalies described with MURCS association genitourinary fistula is not yet reported and reviewed in published articles. The relevance of this paper is to show the importance of further investigation in cases of primary amenorrhoea with mullerian agenesis to establish that the patient has MURCS association and not simply MRKH (Mayer Rokitansky-Kusterhauser Syndrome) syndrome. Consequently we should provide guidance to the patients and their families about the best way to conduct the case including genetic counseling and family screening.

The Ten-Step Vaginal Hysterectomy A Newer and Better Approach

Abstract: Aims and Objectives: This study was undertaken to compare with the traditional Heaney‘s method of vaginal hysterectomy and the newer Ten-Step Vaginal Hysterectomy and to emphasize that this is a safe procedure with lesser blood loss, shorter operation time and shorter requirements of analgesia. Study Design: 110 Patients with non descent, first, second and third degree prolapsed uterus from 45 to 72 years of age were subjected to this study in Khalishpur Clinic. Those women were randomly selected. Among them 54 women had the traditional Heany‘s Methods of Vaginal Hysterectomy and 56 women had the Ten-Step Vaginal Hysterectomy (TSVH). The blood loss was measured by hemoglobin assessment before and 3 days after operation. Material and Methods: In Ten-Step Vaginal Hysterectomy the vaginal wall was incised by drop-like incision starting under the urethra, continuing laterally and down, encircling the cervix from behind and returning back to the starting point from the other side, then separation was done laterally to the side to the uterus. Bladder is detached from the uterus, and the posterior peritoneum is opened. The sacro-uterine ligaments and the paracervical ligaments are clamped together, cut and ligated in both sides. Next the uterine arteries are clamped, cut and ligated. Uterus is pulled down and two fingers are introduced behind the fundus to lift anterior peritoneum and opened under supervision. The round and ovarian ligaments and blood vessels are clamped together and ligated in both side. The peritoneum is left open, then reconstruction of the pelvic floor is done and the vaginal wall is closed continuously. Results: It was found that in comparison of traditional methods with the ten steps vaginal hysterectomy, there are lesser blood loss (400ml vs 80ml; P<0.05) with lower complications, shorter operation time (52.5min vs 30.3min; P<0.05), lesser pain and lesser requirements of analgesia (5.8 vs 3.9 days; P<0.05) and shorter period of convalescence. Hospital stay remains same for both groups. Conclusion: The Ten-Step Vaginal Hysterectomy is a better operation than traditional method of vaginal hysterectomy, Abdominal Hysterectomy and LAVH. At the same time this method is logical and easy to learn, to perform and to teach. DOI: http://dx.doi.org/10.3329/jbcps.v30i2.11407 J Bangladesh Coll Phys Surg 2012; 30: 71-77

Results of internal fixation and anterior muscle pedicle bone grafting in old femoral neck fracture

Abstract: Sixteen cases of old fracture neck femur were treated by internal fixation and anterior muscle pedicle bone grafting of rectus femoris, sartorius bone block from anterior superior iliac spine. The treatment period were from January 2000 to December 2009 at Khulna Medical College Hospital and some private hospital. Different methods of fixation and bone grafting procedure were reported. We did this procedure by open reduction and internal fixation by cannulated hip screws and muscle pedicle bone grafting. Additional cancellous bone grafting were done in every cases. Follow up period was 2 to 7 years (average 5 years). Evaluation parameter were union, non union. collapse of neck, avascular necrosis of femoral head (AVN) coxavara, shortening, pain, range of movement and functional activities and over all satisfaction of patient. The results of fracture healing rate was good (9), fair (4) and poor (3). The technique is simple, rewarding and easy access of fixation and muscle pedicle bone grafting. Bone graft was placed by making a gutter at fracture site and maintained by a screw or prolin suture. DOI: http://dx.doi.org/10.3329/bmjk.v43i1-2.13016 Bang Med J (Khulna) 2010; 43: 10-11