Khulna Medical College

About: Khulna Medical College is a healthcare organization based out in Khulna, Bangladesh. It is known for research contribution in the topics: Hysterectomy & Cancer. The organization has 266 authors who have published 203 publications receiving 964 citations. The organization is also known as: Khulna Medical College, Khulna & KMC.

Cadaver Study on the Branching Pattern of the Splenic Artery in a Bangladeshi Population

Abstract: The spleen is the largest single mass of lymphoid tissue in all vertebrates. Arterial blood supply correlates with the functional capability of the human spleen. A cross-sectional, descriptive type of study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from January to December 2008, to see the arterial pattern in the human spleen. 30 human spleens were collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine of Dhaka Medical College, Dhaka. The samples were divided into three age-groups including group A (15-29 years), group B (30-49 years) & group C (50-69 years). Then macroscopic dissection was done and radiological angiograph was taken to see the arterial pattern in the human spleen. The splenic artery was the origin of sole blood supply in all the specimens. Two lobar branches were found in 70% of specimens and three branches in 23%. Four lobar branches were evident in only 2 specimens. Moreover, several segmental branches and polar arteries were found in the spleen of different ages. The distance between the splenic artery (before giving its lobar branches) and the hilum of the spleen were found 2.99±0.73 cm, 3.79±1.43 cm and 3.51±1.66 cm in group A, B and C respectively. However, the difference was not statistically significant among the study groups. DOI: http://dx.doi.org/10.3329/medtoday.v26i1.21305 Medicine Today 2014 Vol.26(1): 15-17

Laparoscopic Management of Tubal Ectopic of Heterotopic Pregnancy

Abstract: A heterotopic pregnancy is a rare complication of pregnancy in which both extra-uterine (ectopic pregnancy) and intrauterine pregnancy occur simultaneously. The prevalence of heterotopic pregnancy is estimated at 0.6- 2.5: 10,000 pregnancy. It is a challenge for obstetrician to manage the tubal pregnancy without interruption of intrauterine pregnancy. Here we describe a case who had left tubal alive ectopic pregnancy & also intrauterine alive pregnancy simultaneously after a natural conception. This patient was managed successfully with laparoscopic left salpingectomy, and intrauterine pregnancy has been continuing. There are some precautions during laparoscopic procedure & post operative period which can help for continuation of intrauterine pregnancy. In our clinical experience, this is an extreme rare disorder and we feel interest to report this case. A heterotopic pregnancy can result from a natural conception; it requires a high index of suspicious for early and timely diagnosis; a timely intervention can result in a successful outcome of the intrauterine fetus. J Bangladesh Coll Phys Surg 2016; 34(4): 218-221

Effect of intralesional bleomycin as an alternative therapy for cystic hygroma

Abstract: Cystic hygroma is a congenital malformation of the lymphatic system. Surgical excision is the treatment of choice, but injection of a sclerosing agent into the cyst is an alternative procedure. The aim of this study was to review the efficacy of intralesional bleomycin injection in cystic hygroma. This study was carried out in a private clinic in Khulna over a period of 2 years on 7 patients. Bleomycin at a dosage of 0.4-0.6 mg/kg was injected into the cyst and repeated injection was given at an interval of 4-8 weeks. Clinical outcomes were reviewed and analyzed. Seven patients, 4 males and 3 females, aged between one month and 4 years were treated with intralesional bleomycin injections. Complete clinical resolution was obtained in 6 cases (86%). Mass reduction was noted in 1 (14%) patient. Adverse reactions including mild fever, local swelling, redness and pain at the site of injection occurred in 3 cases (43%). These reactions persisted for only a few days. Transient systemic side effect like vomiting noted in one patient. So intralesional bleomycin injection is a safe and effective alternative to the surgical treatment of cystic hygroma. DOI: http://dx.doi.org/10.3329/bmjk.v46i1-2.18233 Bang Med J (Khulna) 2013; 46 : 12-15

Interventional radiology for the treatment of hepatic malignancy.

Abstract: Hepatic malignancies are commonly faced clinical problem. Non surgical minimally invasive therapies are current treatment goal. Interventional radiologists are going forwards with such minimally invasive but effective therapies by transarterial chemoembolization, radiofrequency ablation, percutaneous ethanol injection, cryoablation, laser ablation and upcoming promising procedures like focused ultrasound & gene therapy. Response rates of transarterial chemoembolization for primary and most metastatic tumors are 60-80% with survival rates of 70% at 1 year, 40% at 3 years, and 10% at 5 years. Percutaneous ethanol injection ablation is the most accepted minimally invasive method worldwide, for hepatocellular carcinomas less than 5 cm in diameter, the complete ablation rate is about 70-75%; in 5-8 cm diameter, encapsulated hepatocellular carcinomas, the rate is about 60%. RFA is becoming a widely used ablative technique for primary and secondary liver tumors, with a 52-67% complete ablation rate at 1 year and survival rates of 96%, 64%, and 40% at 1, 3 and 5 years, respectively. Meticulous patient selection, careful planning and execution are imperative and should be carried out with the participation of interventional and diagnostic radiologists, nuclear medicine specialists, and medical, surgical, and radiation oncologists. In terms of cost, equipment, technical efficiency, efficacy & repeated applicability percutaneous procedures particularly PEI & RFA can be carried out in Bangladesh.

Evaluation of scrotal reconstruction with thigh flap

Abstract: Background: Scrotal skin can be lost in many ways. Partial loss of scrotum is easy to manage but major scrotal skin loss represents a significant challenge to the reconstructive surgeon. Although many techniques have been established for the treatment of major scrotal defects, each technique has its own advantages and disadvantages in specific situations. Objective: The aim of this prospective study was to evaluate the outcome of thigh fascio-cutaneous flap for reconstruction of major scrotal loss with exposed testis. Methods: This prospective study was done for 5 years extending from January 2012 to December 2016. In this period we reconstructed major scrotal defects of eight patients with antero medial and pudendal thigh fascio-cutaneous flap in Burn and Plastic Surgery department, Khulna Medical College Hospital. Total eleven thigh fascio-cutaneous flaps were used for reconstruction of major scrotal defects. Results: The mean patient age was 41 years (range 24 to 62 years). The aetiology of scrotal loss was Fournier's gangrene in 4 cases and trauma in 4 cases. Three cases had bilateral and five cases had unilateral flap reconstruction. The flaps allowed sensate coverage and took well. Primary donor site closure obviated the need for skin grafts in most of the cases, Complications were flap tip necrosis (12.50%) and minor wound infection (12.50%) which were treated conservatively. Donor site scar was limited and acceptable. The flap had good aesthetic appearance except in one fatty patient where the flaps were bulky. Conclusion: The study concluded that thigh fascio-cutaneous flap is very reliable for coverage of major scrotal defects. Bang Med J (Khulna) 2017; 50 : 13-17