Khulna Medical College

About: Khulna Medical College is a healthcare organization based out in Khulna, Bangladesh. It is known for research contribution in the topics: Hysterectomy & Cancer. The organization has 266 authors who have published 203 publications receiving 964 citations. The organization is also known as: Khulna Medical College, Khulna & KMC.

Prevalence of Migraine and its associated factors among medical students of Bangladesh: A cross sectional study

Abstract: Introduction Medical students are vulnerable group to migraine, one of the most common type of headache worldwide. The aim of the present study was to determine the prevalence of migraine and related disability among medical students of Bangladesh. Methods This cross-sectional study was conducted among 1327 students from six medical colleges Bangladesh during March 2021 through a self-administered online survey. ID Migraine™ scale and MIDAS scale were used to screen migraine and migraine related disability respectively. Frequency distribution, and Chi-square test, t-test along with multiple logistic regressions model were used to determine the prevalence and associated factors of migraine respectively. Results The overall prevalence of migraine among the participants was 19%. The prevalence was higher among females (27%) than males (8%). Female sex (aOR 4.11, 95% CI 2.79-6.03) and poor sleep quality (aOR 2.07, 95% CI 1.48-2.91) were identified as independent risk factors of migraine. More than 90% migrainures reported to suffer from moderate to severe headache. Nausea was most commonly reported associated symptom (83.5%) followed by photophobia (72%) and vomiting (53%). Self-reported mental stress (55%), irregular sleep (49%), noise (30.5%), and usage of electronic device (30.5%) were most commonly reported triggering factor of migraine attack. More than half of the sufferers reported severe migraine related disability (MIDAS score ≥ 21). Conclusions The prevalence of migraine among medical students of Bangladesh is alarmingly high. Frequent migraine attacks and severe intensity of headache cause a substantial level of disability among the sufferers. Cautious avoidance of the triggering factors through appropriate interventions and prophylactic medication can mitigate the negative impact of migraine as well as improve the quality of life.

The Role of Sentinel Lymph Node Biopsy in the Management of Breast Cancer

Abstract: The sentinel lymph node (SLN) is defined as the first node(s) receiving lymphatic drainage from a primary tumour. A promising alternative to axillary lymph node dissection (ALND) is sentinel lymph node biopsy. SLN biopsy has been introduced as a technique to identify axillary lymph node most likely to contain tumour cells metastasizing from a primary carcinoma of breast. Several methods of identifying the SLN exists, including the use of radioactive tracer, lymphazurin dye or combination of the two via intraparenchymal and/or intradermal, peritumoral or periaerolar injection sites. Intraoperative evaluation of SLNs are done by performing FS(Frozen Section) on all the lymph nodes after serially sectioning them at 3-4mm intervals; at least 2 levels are cut of all the sentinel lymph nodes. In addition, touch preparation cytology(TP) smear may also be made for evaluation. The limitations of SLNB is that a proportion of patients who have metastasis limited to the SLN can be predicted when there is a combination of tumour size <1.0cm, the absence of lymphovascular invasion and micrometastatic disease (<0.2cm) in SLN. However for patients with large breast cancer, the role of SLNB is controversial. Early studies of SLNB in large breast cancer patients demonstrated a high (8-18%) false negative rate, with the accuracy worsening with the increasing size. Excision of SLNs have an extremely low morbidity and a high degree of staging accuracy. A tumour-free SLN virtually excludes lymphatic involvement of the entire regional lymphatic basin. More than 50 observational studies of SLNB validated by a back up ALND demonstrate that SLNB is feasible, accurate and suitable for virtually all patients with operable clinically node negative disease. Sentinel lymph node biopsy not only provide prognostic information, but also aims to guide adjuvant therapy without the untoward side effects of complete axillary dissection. J Bangladesh Coll Phys Surg 2014; 32: 211-217

Caesarean Scar Pregnancy - A Rare Case Report

Abstract: Objective: The aim is to publish the case report of the rarely occurring and life threatening ectopic pregnancy developing in a Caesarean section scar causing uterine rupture. Methods and Results: This patient was diagnosed initially as a case of incomplete abortion. Other possible diagnoses were molar pregnancy, mass in the cervix. She was admitted in hospital for evacuation and curettage. During the procedure she developed severe pervaginal bleeding leading to hypovolumic shock. So decision was taken for emergency laparotomy. After opening the abdomen rupture was found in the lower uterine segment extending upto upper part of cervix. So hysterectomy was performed and histopathology confirmed the diagnosis of ectopic pregnancy that developed in a Caesarean section scar Analysis of the women’s obstetric history revealed that she had been previously operated because of breech presentation. Conclusion: Heightened awareness of the possibility of pregnancy in caesarean scar and early diagnosis by means of transvaginal sonography along with colour doppler can improve outcome and minimize the need for emergency extended surgery Bangladesh J Obstet Gynaecol, 2012; Vol. 27(2) : 83-86

Magnitude of cancer patients in a teaching hospital

Abstract: This was an observational study carried out among all cancer patients attended at radiotherapy department of Khulna medical college hospital between January 2010 and December 2010. The study aimed to develop a primary data source for further research and improvement of patient care. Data were collected by a questionnaire. Total study population was 321 and out of them 158 was male and 163 were female. Top five organs involved with malignancies of both sexes are breast (14.64%), non-Hodgkin’s Lymphoma (1 0.59%), lung (7.79%), mouth and oral cavity (7.48%), and stomach (7.48%). This hospital-based cancer registry should be maintained to improve the treatment facilities and follow-up system. DOI: http://dx.doi.org/10.3329/bmjk.v44i1-2.10471 Bang Med J (Khulna) 2011: 44(1&2) 18-24

Outcome of management of congenital diaphragmatic hernia

Abstract: Congenital Diaphragmatic Hernia (CDH) is a defect in the dome of diaphragm, more often in left and postero-lateral that permits the herniation of abdominal contents into the thorax. The lungs hypoplasia, pulmonary hypertension and persistent foetal circulation are important determinant of survival. The incidence is <5 in 10,000 live-births. Antenatal diagnosis is ofen made and this may be helpful in postnatal management. Treatment after birth requires all the refinements of critical care prior to surgical correction. The best hospital series report 80-100% survival. Advances in surgical management include delayed surgical approach that enables preoperative stabilization, improved prenatal diagnosis, introduction of minimal invasive surgery and application of extracorporeal membrane oxygenation in addition to the standard open repair. In our short series survival was 100% where surgical correction was made on selective 12 cases of left sided CDH in a non-ICU set-up. DOI: http://dx.doi.org/10.3329/bmjk.v47i1-2.22556 Bang Med J (Khulna) 2014; 47 : 12-15