Khulna Medical College

About: Khulna Medical College is a healthcare organization based out in Khulna, Bangladesh. It is known for research contribution in the topics: Hysterectomy & Cancer. The organization has 266 authors who have published 203 publications receiving 964 citations. The organization is also known as: Khulna Medical College, Khulna & KMC.

Outcome of meconium ileus in a tertiary care hospital

Abstract: Background: Meconium ileus is a common form of congenital intestinal obstruction. The condition results from the accumulation of sticky inspissated meconium in distal ileum. In about half the cases, however, the pathologic condition is complicated by volvulus, gangrene, perforation with meconium peritonitis. Relief of the obstruction is commonly accomplished with a variety of operative procedures. A number of operative procedures are in use, including Bishop-Koop enterostomy, Mikulicz ileostomy and primary closure Objective: Aim of this study was to evaluate the outcome of meconium ileus and its complications in two commonly practiced enterostomy procedure. Method: In this retrospective study from July 2007 to Jun 2017, a total of 52 cases of meconium ileus were included. Diagnosis of suspected cases was confirmed after laparotomy. Two commonly practiced ileostomy procedure were Mikulicz ileostomy and Bishop Koop ileostomy in this study. Survivors of all primary enterostomy underwent ileostomy closure after 3-6 months. Result: Mikulicz enterostomy was done in 38 cases and Bishop Koop ileostomy in 14 cases. After primary ileostomy 5 patients died following Mikulicz ileostomy and 2 after Bishop Koop ileostomy Among the 41 cases those who reached ileostomy closure, 35 were survived. Conclusion: Complications were more common after Mikulicz ileostomy and difficult to manage in our observation. Overall survival of meconium ileus was 66% in our study without any facilities of intensive neonatal care. Bang Med J (Khulna) 2017; 50 : 31-34

FAHR'S Sy ndrome: A rare Neurodegenerative Disorder

Abstract: Idiopathic Basal Ganglia Calcification, also known as Fahr disease or Fahr's Syndrome or Bilateral StriatoPallidoDentate Calcinosis (BSPDC) is a rare, genetically dominant, inherited neurological disorder characterized by abnormal deposits of calcium in areas of the brain that control movement, including the basal ganglia and the cerebral cortex. A rare idiopathic disease which manifests in middle age characterized by punctate areas of non-arteriosclerotic calcination in parts of the gray and dentate nuclei, particularly of smaller brain vessels. The symptoms include mental and growth retardation, dystonic movements, and athetosis. May be caused by a malfunction of the glandula parathyreoidea. The term Fahr triad consists of symmetrical calcification of the basal ganglia, neuropsychiatric symptoms, and hypofunction of the parathyroid gland. Treatment is directed toward minimizing symptoms. The prognosis for any individual with Fahr's Syndrome is variable and hard to predict. Progressive neurological deterioration generally results in disability and death. Medicine Today 2017 Vol.29(1): 39-41

Cutaneous atypical mycobacteriosis

Abstract: Mycobacterium chelonae rarely causes skin infection, usually after minor trauma. A 44 year old lady complained of skin rashes on left lateral back above the flank for 6 months. Physical examination showed multiple papulo-pustular eruption and sinus on an erythematous base. Repeated histopathological examination did not give any authentic clue. Ultimately on clinical ground and therapeutic trial, it was diagnosed as rapidly growing atypical mycobacterial (Mycobacterium chelonae) infection. Bang Med J (Khulna) 2017; 50 : 44-45

Histomorphometric study of the human spleen

Abstract: Context: The spleen is the largest single mass of lymphoid tissue in all vertebrates. Histological changes are evident in advancing age along with functional capability of the human spleen. A cross-sectional, descriptive type of study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from January to December 2008, to see the age related microscopic changes in the human spleen. Methods: 30 human spleens were collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine of Dhaka Medical College, Dhaka. The samples were divided into three age-groups including group A (15-29 years), group B (30-49 years) & group C (50-69 years). Then 5 best prepared histological slides from each group were taken and examined under the light compound microscope to determine the thickness of capsule, diameter, number and percent amount of white pulp in the human spleen. Results: The thickness of the splenic capsule were found 84.60±7.97 ?m, 117.92±4.16 ?m, and 132.17±6.37 ?m in group A, B and C respectively. The diameter of the white pulp were found 0.32±0.01 mm, 0.32±0.01 mm and 0.31±0.01 mm, while the number of white pulp per sq. mm were 2.28±1.04, 2.38±0.93 and 2.04±0.76 in group A, B and C respectively. Moreover, the amounts of the white pulp were determined 23.09±1.38, 24.45±1.84 and 22.54±1.08 in group A, B and C respectively. The difference in thickness of the splenic capsule was statistically significant among the study groups (p<0.001). However, no difference was found in diameter, number and percentage of the white pulp of the spleen among those age groups. Conclusion: The thickness of the capsule of the spleen was found to increase with advancing age in humans. However, no age change was evident in diameter, number or amount of the white pulp. DOI: http://dx.doi.org/10.3329/bjms.v11i4.12600 Bangladesh Journal of Medical Science Vol. 11 No. 04 Oct’12

Causal factors and treatment outcome of genitourinary fistula in a teaching hospital

Abstract: Background: Urogenital fistula, majority of which is vesicovaginal fistula is a public health problem especially of developing countries. It is commonly caused by prolonged and obstructed labor. With the advancement of health care delivery system etiology of urogenital fistula is changing in our country. Objective: This study was done to find out the causal factors and to determine the success rate of operative procedure for treatment of urogenital fistula. Method: This was an observational type of cross sectional study, carried out in Department of Obs and Gynae in Khulna Medical College Hospital from January 2013 to June 2014 among 30 women at different ages suffering from urogenital fistula due to gynaecological or obstetrical causes or malignancy. Result: Majority of the patients were young primipara, short stature and malnourished, coming from lower socioeconomic condition of rural areas. Prolonged labor 12 (40%) was the most common cause of urogenital fistula, followed by gynaecological surgeries mainly hysterectomies 9 (30%) and malignancy 2 (6.6%) rare cause. The success rate of repair following first and second attempt was 92% and 8% respectively. Overall success rate was 24 (96%) and functionally failed with a failure in 1 (4%) cases. This study showed main cause for developing fistula showing prolonged labor and majority of patient were treated pervaginally. Most of the cases (96%) had successful repair which is very encouraging and correlates well with recently published series. Conclusion: Fistula can be totally preventable by proper antenatal care, identification of high risk cases, timely referral, proper intranatal, postnatal care, and proper training. So improvement of health care services and dedication will prevent this type of morbidity. The best results are obtained when repair of urogenital. fistulae is carried out under optimal conditions. Bang Med J (Khulna) 2017; 50 : 18-21