Institution
King Faisal Specialist Hospital & Research Centre
Healthcare•Riyadh, Saudi Arabia•
About: King Faisal Specialist Hospital & Research Centre is a healthcare organization based out in Riyadh, Saudi Arabia. It is known for research contribution in the topics: Detection limit & High-performance liquid chromatography. The organization has 58 authors who have published 157 publications receiving 3527 citations.
Topics: Detection limit, High-performance liquid chromatography, Chiral resolution, Enantiomer, Medicine
Papers published on a yearly basis
Papers
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TL;DR: In this article, a high-throughput, high performance liquid chromatographic method was developed and validated for the determination of clopidogrel in pharmaceutical dosage forms at room temperature using a reversed phase monolithic silica column Chromolith Performance 18e (100mm×4.6mm I.D.).
Abstract: A high‐throughput, high performance liquid chromatographic method was developed and validated for the determination of clopidogrel in pharmaceutical dosage forms. The analysis was performed at room temperature using a reversed phase monolithic silica column Chromolith Performance 18e (100 mm×4.6 mm I.D.). The mobile phase consisted of acetonitrile:phosphate buffer (50∶50 v/v, pH 3.0) at a flow rate of 4.0 mL/min. The photodiode array detector was set at 235 nm. The developed method showed a good linear relationship in the concentration range from 1.0 to 40.0 µg/mL with a correlation coefficient of 0.999. The limit of detection and limit of quantification were 0.97 µg/mL and 3.52 µg/mL, respectively.
15 citations
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TL;DR: In this article, a capillary zone electrophoretic (CZE) method for the determination of rutin in an ethanolic extract of the aerial parts of Hypericum perforatum (Hypericaceae) is described.
Abstract: A capillary zone electrophoretic (CZE) method for the determination of rutin in an ethanolic extract of the aerial parts of Hypericum perforatum (Hypericaceae) is described. The analysis was performed using a fused-silica capillary and a background electrolyte consisted of 10% ethanol and 20 mM borate buffer at pH 8.0 applied at a potential of 28 kV, vacuum injection of 1 s and detecting at 200 nm. Rutin had a migration time of 10.1 ± 0.2 min. Reproducibility was 1.26% for 9.37 × 10−5 M standard rutin. Detection limit was 2.7 × 10−6 M (S/N = 3). A well-correlated calibration equation was obtained for the mentioned conditions. The amount of rutin in the total plant material was found to be 0.21% ± 0.02.
14 citations
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TL;DR: In this article, the chiral resolution of cromakalim has been achieved on macrocyclic glycopeptide antibiotics columns, namely teicoplanin and teic-pilin aglycon known as Chirobiotic T and Chiro-biotic TAG, respectively.
Abstract: The chiral resolution of cromakalim has been achieved on macrocyclic glycopeptide antibiotics columns, namely teicoplanin and teicoplanin aglycon known as Chirobiotic T and Chirobiotic TAG, respectively. The mobile phases used were hexane–ethanol (95 : 5, v/v) on Chirobiotic T and hexane–ethanol (75 : 25, v/v) on Chirobiotic TAG columns, respectively, at a flow rate of 0.5 mL/min. The detection was carried out at 220 nm. The α values of the resolved enantiomers were 1.13 and 1.12 on Chirobiotic T and Chirobiotic TAG columns, respectively. The values of Rs were 1.27 and 1.25 on Chirobiotic T and Chirobiotic TAG columns, respectively. The detection of the enantiomers was better on Chirobiotic T column than on Chirobiotic TAG column.
14 citations
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TL;DR: Mixed longitudinal data on growth and anthro pometric measurements are presented for 6400 infants and pre-school children from Riyadh, capital city of the Kingdom of Saudi Arabia.
Abstract: A SURVEY OF Growth and Development of Saudi Infants and Pre-School Children is currently being conducted in Riyadh, with the objective of develop ing a growth chart for Saudi infants and pre-school children. Mixed longitudinal data on growth and anthro pometric measurements are presented for 6400 infants and pre-school children from Riyadh, capital city of the Kingdom of Saudi Arabia. This paper focuses on field survey research design and some methodological aspects of the study; sample structure, sampling design and pro cedures for data collection are discussed.
13 citations
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TL;DR: This review discusses the analysis of chiral pollutants using gas chromatography, high performance liquid Chromatography (HPLC), capillary electro-chromatography (CEC), micellar electrokinetic chromatography (MEKC), super critical fluid chromatography(SFC) and thin layer chromalysis (TLC).
Abstract: Many organic environmental pollutants are mixtures of their chiral isomers. Studies have revealed that these isomers have different enantioselective distribution, metabolism and toxicity. Today, analysis of chiral pollutants represents an urgent need. This review discusses the analysis of chiral pollutants using gas chromatography (GC), high performance liquid chromatography (HPLC), capillary electro-chromatography (CEC), micellar electrokinetic chromatography (MEKC), super critical fluid chromatography (SFC) and thin layer chromatography (TLC).
13 citations
Authors
Showing all 81 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hassan Y. Aboul-Enein | 56 | 876 | 16492 |
Roger W. Byard | 54 | 1002 | 16437 |
Shahrukh K. Hashmi | 33 | 268 | 4176 |
Ashraf Ghanem | 32 | 117 | 3166 |
Abderrezak Bouchama | 31 | 70 | 5690 |
Pinar Ozand | 26 | 160 | 2273 |
Claire Simons | 23 | 90 | 2018 |
Asim F. Belgaumi | 16 | 54 | 1009 |
Saeed Ahmed | 16 | 67 | 716 |
Christer Ullbro | 13 | 22 | 746 |
Imran Ali | 13 | 36 | 848 |
Gael E. Phillips | 13 | 24 | 629 |
J. Brismar | 11 | 12 | 356 |
Tariq Ali | 11 | 15 | 1704 |
Yunus M. Siddiqui | 11 | 15 | 445 |