Institution
King Faisal Specialist Hospital & Research Centre
Healthcare•Riyadh, Saudi Arabia•
About: King Faisal Specialist Hospital & Research Centre is a healthcare organization based out in Riyadh, Saudi Arabia. It is known for research contribution in the topics: Medicine & Detection limit. The organization has 58 authors who have published 157 publications receiving 3527 citations.
Topics: Medicine, Detection limit, High-performance liquid chromatography, Chiral resolution, Enantiomer
Papers published on a yearly basis
Papers
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Yahoo!1, King Faisal Specialist Hospital & Research Centre2, King Saud University3, Cleveland Clinic4, King Abdulaziz Medical City5, Tanta University6, King Abdulaziz University7, King Fahad Specialist Hospital8, Sultan Qaboos University9, Adan Hospital10, IBN Sina Medical College11, Banha University12, National Institutes of Health13, Tufts University14
TL;DR: In this article, the authors evaluated clinical outcomes of ULMCA PCI as compared to CABG in patients requiring revascularization in three Gulf countries, and found that no difference was observed in freedom from revascularisation, major adverse cardiovascular and cerebrovascular events (MACCE) or total mortality between those treated with PCI and CabG.
4 citations
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01 Jan 20044 citations
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TL;DR: In this paper , the authors evaluated clinical outcomes of ULMCA PCI as compared to CABG in patients requiring revascularization in three Gulf countries, and found that no difference was observed in freedom from revascularisation, major adverse cardiovascular and cerebrovascular events (MACCE) or total mortality between those treated with PCI and CabG.
4 citations
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TL;DR: In this article, the enantiomers of cromakalim (3S,4S and 3R,4R) were resolved on polysaccharide chiral stationary phases (CSPs) under reversed phase mode.
Abstract: Cromakalim is an antihypertensive drug (potassium channel activator) that acts as potent vasodilator functioning by hyperpolarization of vascular smooth muscle membranes and opening of potassium channels. Attempts have been made to resolve the enantiomers of cromakalim (3S,4S and 3R,4R) on polysaccharide chiral stationary phases (CSPs) under reversed‐phase mode. The columns used were Chiralpak AD‐R, Chiralcel OD‐R, and Chiralcel OJ‐R. The mobile phases used were water–acetonitrile (70:30, v/v) for the Chiralpak AD‐R and the Chiralcel OD‐R columns, and water–acetonitrile (80:20, v/v) for the Chiralcel OJ‐R column. The flow rate of the mobile phases was 0.5 mL/min. The detection was carried out at 220 nm. The α‐values of the resolved enantiomers were 1.26, 1.23, and 1.13 on Chiralpak AD‐R, Chiralcel OD‐R, and Chiralcel OJ‐R columns, respectively, while the values of R s were 1.20, 0.40, and 0.30 on Chiralpak AD‐R, Chiralcel OD‐R, and Chiralcel OJ‐R columns, respectively. Concentration of cromakalim...
4 citations
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TL;DR: A rapid, sensitive and stability indicating high performance liquid chromatographic method was developed and validated for the analysis of dehydroepiandrosterone (DHEA) in pharmaceutical tablet formulation and the role of acetic acid as an organic phase modifier was investigated.
Abstract: A rapid, sensitive and stability indicating high performance liquid chromatographic method was developed and validated for the analysis of dehydroepiandrosterone (DHEA) in pharmaceutical tablet formulation. The analysis was done on a Supelcosil C(18) column (25 cm x 4.6 mm i.d., 5 microm). The mobile phase consisted of methanol:sodium acetate buffer solution (5 g/L):acetic acid (500 mL/L), 57:42:1, v/v/v, adjusted to pH 5 at a flow rate of 1 mL/min. Detection was carried out at a wavelength of 258 nm. The polynomial regression data for the calibration curve showed good linear relationship in the concentration range of 0.2-1 mg/mL with r = 0.9996. The method was validated for precision, accuracy and recovery. The limit of detection was found to be 50 ng/ microL. The method was applied for the analysis of DHEA in its pharmaceutical tablet formulation. The effects of different buffers and alcohols on the retention of DHEA were studied and the role of acetic acid as an organic phase modifier was also investigated.
4 citations
Authors
Showing all 81 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hassan Y. Aboul-Enein | 56 | 876 | 16492 |
Roger W. Byard | 54 | 1002 | 16437 |
Shahrukh K. Hashmi | 33 | 268 | 4176 |
Ashraf Ghanem | 32 | 117 | 3166 |
Abderrezak Bouchama | 31 | 70 | 5690 |
Pinar Ozand | 26 | 160 | 2273 |
Claire Simons | 23 | 90 | 2018 |
Asim F. Belgaumi | 16 | 54 | 1009 |
Saeed Ahmed | 16 | 67 | 716 |
Christer Ullbro | 13 | 22 | 746 |
Imran Ali | 13 | 36 | 848 |
Gael E. Phillips | 13 | 24 | 629 |
J. Brismar | 11 | 12 | 356 |
Tariq Ali | 11 | 15 | 1704 |
Yunus M. Siddiqui | 11 | 15 | 445 |