King Faisal Specialist Hospital & Research Centre

About: King Faisal Specialist Hospital & Research Centre is a healthcare organization based out in Riyadh, Saudi Arabia. It is known for research contribution in the topics: Detection limit & High-performance liquid chromatography. The organization has 58 authors who have published 157 publications receiving 3527 citations.

Effect of psoralens on Fenton-like reaction generating reactive oxygen species.

Abstract: Psoralens (psoralen, 5-methoxypsoralen, 8-methoxypsoralen, khellin, and visnagin) in 1 mM doses were shown to enhance the generation of reactive oxygen species, such as the hydroxyl radical (HO·), the superoxide anion radical ( ), and singlet oxygen (1O2), from the system generating chemiluminescence (CL), as well as free radicals in the absence of light. The system that generated CL was made up of CoCl2 and H2O2. Incubation of psoralens in 0.2 mM doses with the generating system showed that only 8-methoxypsoralen and khellin have antioxidative effects. Antioxidative effects were also observed in the case of visnagin but in low concentration (0.05 mM). High doses of psoralens (1 mM) showed prooxidative effects. Measurements were done using a deoxyribose assay, the CL method, and spin-trapping with 5,5-dimethyl-1-pyrroline-N-oxide and 2,2,6,6-tetramethylpiperidine combined with electron spin resonance spectroscopy and spectrophotometry methods. © 2002 Wiley Periodicals, Inc. Biopolymers (Biospectroscopy) 72: 59–68, 2003

Determination of metal ions in water, soil, and sediment by capillary electrophoresis

Abstract: The determination of metal ions in the environmental samples by capillary electrophoresis is an important area for the environmental chemists. The determination of metal ions in water, soil and sediment samples by capillary electrophoresis is reviewed. Various aspects of analysis such as sample pre-treatment, metal ion complexation, detection, choice of visualizing agents, detection limit and choice of electrolytes have been discussed. Suggestions to improve the application of CE for metal ions analysis are given. The future scope of this technique has also been discussed.