Korea University

About: Korea University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Thin film. The organization has 39756 authors who have published 82424 publications receiving 1860927 citations. The organization is also known as: Bosung College & Bosung Professional College.

Measurement of the elliptic anisotropy of charged particles produced in PbPb collisions at √sNN=2.76 TeV

Abstract: The anisotropy of the azimuthal distributions of charged particles produced in √s_(NN)=2.76 TeV PbPb collisions is studied with the CMS experiment at the LHC. The elliptic anisotropy parameter, v_2, defined as the second coefficient in a Fourier expansion of the particle invariant yields, is extracted using the event-plane method, two- and four-particle cumulants, and Lee-Yang zeros. The anisotropy is presented as a function of transverse momentum (p_T), pseudorapidity (η) over a broad kinematic range, 0.3

Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

Abstract: Recent advances in microfluidic cell cultures enable the construction of in vitro human skin models that can be used for drug toxicity testing, disease study. However, current in vitro skin model have limitations to emulate real human skin due to the simplicity of model. In this paper, we describe the development of 'skin-on-a-chip' to mimic the structures and functional responses of the human skin. The proposed model consists of 3 layers, on which epidermal, dermal and endothelial components originated from human, were cultured. The microfluidic device was designed for co-culture of human skin cells and each layer was separated by using porous membranes to allow interlayer communication. Skin inflammation and edema were induced by applying tumor necrosis factor alpha on dermal layer to demonstrate the functionality of the system. The expression levels of proinflammatory cytokines were analyzed to illustrate the feasibility. In addition, we evaluated the efficacy of therapeutic drug testing model using our skin chip. The function of skin barrier was evaluated by staining tight junctions and measuring a permeability of endothelium. Our results suggest that the skin-on-a-chip model can potentially be used for constructing in vitro skin disease models or for testing the toxicity of cosmetics or drugs.

Centrality dependence of π+/-, K+/-, p, and p̄ production from √sNN = 130 GeV Au + Au collisions at RHIC

Abstract: Identified ${\ensuremath{\pi}}^{+/\ensuremath{-}}$, ${K}^{+/\ensuremath{-}}$, $p$, and $\overline{p}$ transverse momentum spectra at midrapidity in $\sqrt{{s}_{\mathrm{NN}}}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}130\phantom{\rule{0ex}{0ex}}\mathrm{GeV}\phantom{\rule{0ex}{0ex}}\mathrm{Au}+\mathrm{Au}$ collisions were measured by the PHENIX experiment at RHIC as a function of collision centrality. Average transverse momenta increase with the number of participating nucleons in a similar way for all particle species. Within errors, all midrapidity particle yields per participant are found to be increasing with the number of participating nucleons. There is an indication that ${K}^{+/\ensuremath{-}}$, $p$, and $\overline{p}$ yields per participant increase faster than the ${\ensuremath{\pi}}^{+/\ensuremath{-}}$ yields. In central collisions at high transverse momenta $({p}_{T}\ensuremath{\gtrsim}2\mathrm{GeV}/c)$, $\overline{p}$ and $p$ yields are comparable to the ${\ensuremath{\pi}}^{+/\ensuremath{-}}$ yields.