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Institution

Kumamoto University

EducationKumamoto, Kumamoto, Japan
About: Kumamoto University is a education organization based out in Kumamoto, Kumamoto, Japan. It is known for research contribution in the topics: Population & Cancer. The organization has 19602 authors who have published 35513 publications receiving 901260 citations. The organization is also known as: Kumamoto Daigaku.


Papers
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Journal ArticleDOI
TL;DR: In this paper, two high-resolution cores from the continental slope of the eastern East China Sea (ECS) were used to reconstruct the surface-water history, showing that the planktic foraminiferal assemblage during the deglacial stage which is represented by high percentages of G. quinqueloba, is quite different from those during the glacial and postglacial stages.

214 citations

Journal ArticleDOI
05 Sep 1997-Cell
TL;DR: This work visualized the subcellular distribution of mini-F-plasmid molecules by fluorescence in situ hybridization and found that molecules of a mini F plasmid lacking the sopABC segment were distributed randomly in spaces not occupied by nucleoids.

214 citations

Proceedings ArticleDOI
03 Jun 2009
TL;DR: A review of the literature on driver inattention monitoring system for the purpose of active safe driving can be found in this paper, where the authors classified driving inattentions into two categories: fatigue and distraction.
Abstract: This paper gives a review of the literature on driver inattention monitoring system for the purpose of active safe driving. In this paper driving inattention is classified into two categories: fatigue and distraction, while fatigue and distraction can also contain many types and levels. Individual difference on inattention phenomenon makes it more complicated to correctly detect and recognize driving inattention. Driver attention monitoring has been intensively researched in recent years and many approaches have been proposed, which include biological signal (EEG, ECG, EOG and sEMG) processing method, subjective report method, and behavior analysis method. This survey reviews a number of promising approaches and provides an overview of recent developments in this domain. The emphasis of this paper is to discuss the various methodologies to monitor driving inattention. We conclude with some thoughts about future directions.

214 citations

Journal ArticleDOI
TL;DR: Homology search for the amino acid sequence of the IL‐5 receptor reveals that the IL-5 receptor contains a common motif of a cytokine receptor family that is recently identified.
Abstract: Murine interleukin-5 (IL-5) is known to play an essential role in Ig production of B cells and proliferation and differentiation of eosinophils. Here, we have isolated cDNA clones encoding a murine IL-5 receptor by expression screening of a library prepared from a murine IL-5 dependent early B cell line. A cDNA library was expressed in COS7 cells and screened by panning with the use of anti-IL-5 receptor monoclonal antibodies. The deduced amino acid sequence analysis demonstrates that the receptor is a glycoprotein of 415 amino acids (Mr 45,284), including an N-terminal hydrophobic region (17 amino acids), a glycosylated extracellular domain (322 amino acids), a single transmembrane segment (22 amino acids) and a cytoplasmic tail (54 amino acids). COS7 cells transfected with the cDNA expressed a 60 kd protein that bound IL-5 with a single class of affinity (KD = 2-10 nM). FDC-P1 cells transfected with the cDNA for murine IL-5 receptor showed the expression of IL-5 binding sites with both low (KD = 6 nM) and high affinity (KD = 30 pM) and acquired responsiveness to IL-5 for proliferation, although parental FDC-P1 cells did not show any detectable IL-5 binding. In addition, several cDNA clones encoding soluble forms of the IL-5 receptor were isolated. Northern blot analysis showed that two species of mRNAs (5.0 kb and 5.8 kb) were detected in cell lines that display binding sites for murine IL-5. Homology search for the amino acid sequence of the IL-5 receptor reveals that the IL-5 receptor contains a common motif of a cytokine receptor family that is recently identified.

214 citations


Authors

Showing all 19645 results

NameH-indexPapersCitations
Fred H. Gage216967185732
George D. Yancopoulos15849693955
Kenji Kangawa1531117110059
Tasuku Honjo14171288428
Hideo Yagita13794670623
Masashi Yanagisawa13052483631
Kazuwa Nakao128104170812
Kouji Matsushima12459056995
Thomas E. Mallouk12254952593
Toshio Hirano12040155721
Eisuke Nishida11234945918
Hiroaki Shimokawa11194948822
Bernd Bukau11127138446
Kazuo Tsubota105137948991
Toshio Suda10458041069
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202315
202297
20211,701
20201,654
20191,511
20181,330