Institution
Kuvempu University
Education•Shimoga, India•
About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.
Papers published on a yearly basis
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TL;DR: Ethanol extract of Catharanthus roseus showed significant anthelminthic activity against Pheretima posthuma, and Ethanol extract also proved to be efficient than the standard drug.
Abstract: Helminthes infections are chronic illnesses in human beings and in cattle. Pherithema posthuma a helminthes is commonly known as earth-worms. Although the use of alternate drugs has been as a remedial measure against the resistant strains of helminth parasites, and as a means of reducing the cost of controlling helminthic diseases. Catharanthus roseus is a medicinally valuable plant and possess various pharmacological properties. Catharanthus roseus has been traditionally used as an anthelminthic agent. To justify the ethnomedical claims, the anthelminthic property of Catharanthus roseus was evaluated using Pherithema posthuma as an experimental model. Piperazine citrate was used as the standard reference. Among the various concentrations tested, ethanol extract at 200 mg/ml showed efficient paralysis effect (6.67 min) than other treated groups, whereas ethanol extract 250 mg/ml showed significant anthelminthic activity with death time of 46.33 min. Standard drug at 50 mg/ml showed paralysis at 31.33 min and death time was 40.67 min. This investigation revealed that ethanol extract of Catharanthus roseus showed significant anthelminthic activity against Pheretima posthuma. Ethanol extract also proved to be efficient than the standard drug. This investigation supported the ethnomedical claims of Catharanthus roseus as an anthelminthic plant.
19 citations
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TL;DR: In this article, the synthesis of series of 3-(5- Substituted -1-benzofuran-2-yl)-1-(4-substituted phenyl)- 1H-pyrazole-4-carbaldehyde derivatives (4a-4j) and (Z)-2-((3-(5-(5]- Substitized benzofuran-(2]-)-1-yl), 1-p-substantituted-1H-polyphenyl)-4-yl) methylene)-2, 3-dihydro
19 citations
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TL;DR: In this article, two series of imidazoles were prepared: i) reaction of thiosemicarbazones (I) with dimethylacetylenedicarboxylate (II) furnishes the imidiazoles (III) in good yields; ii) trisubstituted imidozoles (VI) are obtained by refluxing diketones (IV) with pyrazole carbaldehydes (V) and ammonium acetate via Debus reaction.
Abstract: Two series of imidazoles are prepared: i) reaction of thiosemicarbazones (I) with dimethylacetylenedicarboxylate (II) furnishes the imidazoles (III) in good yields; ii) trisubstituted imidazoles (VI) are obtained by refluxing diketones (IV) with pyrazolecarbaldehydes (V) and ammonium acetate via Debus reaction.
19 citations
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TL;DR: In this paper, a mixture of 3-formyl-2-chloroquinolines with thioglycolic acid was obtained in a 60-70% yield and cyclized thieno[2,3-b]quinoline-2 carboxylic acids in a 30-40% yield.
Abstract: The reaction of 3-formyl-2-chloroquinolines with thioglycolic acid afforded a mixture of uncyclized [(3-formylquinolin-2-yl)thio]acetic acid in a 60–70% yield and cyclized thieno[2,3-b]quinoline-2-carboxylic acids in a 30–40% yield, respectively. The uncyclized compounds on refluxing with POCl 3 in various alcoholic media gave [(3-formylquinolin-2-yl)thio]acetates. Further cyclization was achieved by refluxing them with dimethylformamide (DMF) to produce thieno[2,3-b]quinoline derivatives. On the other hand, the reaction of 3-formyl-2-mercaptoquinolines with chloroacetyl chloride in DMF gave 3-chloro-2H-thiopyrano[2,3-b]quinolin-2-ones. The structures of all the newly synthesized compounds were characterized on the basis of elemental analysis, IR, 1 H NMR, and mass spectral data.
19 citations
Authors
Showing all 1592 results
Name | H-index | Papers | Citations |
---|---|---|---|
Tejraj M. Aminabhavi | 89 | 642 | 32265 |
Subburaman Mohan | 86 | 461 | 29023 |
Suresh Mathivanan | 48 | 116 | 24289 |
Raghothama Chaerkady | 40 | 85 | 8554 |
Bijjanal Jayanna Gireesha | 40 | 233 | 4748 |
Basavarajappa Mahanthesh | 38 | 158 | 3580 |
Thimmappa Venkatarangaiah Venkatesha | 34 | 149 | 3907 |
B.E. Kumara Swamy | 31 | 160 | 3416 |
Shivakumar Keerthikumar | 27 | 55 | 6557 |
Rajesh Raju | 25 | 51 | 6733 |
K. Ganesh Kumar | 24 | 64 | 1298 |
Kalappa Prashantha | 24 | 65 | 2191 |
Jayappa Manjanna | 24 | 73 | 1903 |
Kallappa M. Hosamani | 24 | 105 | 2602 |
Kumaran Kandasamy | 23 | 31 | 5921 |