Kuvempu University

About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.

Gene Expression Profiling of Tuberculous Meningitis

Abstract: Tuberculous meningitis (TBM) is a form of extra pulmonary tuberculosis that is associated with severe neurological deficits and a high mortality. Early diagnosis of TBM is a major challenge despite the availability of several diagnostic methods. Existing diagnostic methods and markers are inadequate for early diagnosis of TBM owing to poor specificity and sensitivity. DNA microarray technology permits high-throughput identification of differentially expressed genes. In order to identify molecules as candidate biomarkers for early diagnosis or as therapeutic targets in TBM, we carried out transcriptomic analysis of brain tissue using whole human genome oligonucleotide arrays. From this gene expression analysis, we identified 2,434 genes that were differentially expressed at least two-fold in TBM cases as compared to controls. The large majority of the differentially expressed genes encoded proteins that are involved in metabolism, cell growth, transport, immune response, cell communication and signal transduction. We confirmed the upregulation of two molecules, serpin peptidase inhibitor, clade A member 3 (SERPINA3) and glial fibrillary acidic protein (GFAP), at the protein level by immunohistochemical analysis. The findings from our study should help us understand the molecular mechanisms underlying TBM and to develop better diagnostic and therapeutic strategies against this deadly disease.

Citation analysis of doctoral theses in botany submitted to Kuvempu University, India: a case study

Abstract: Purpose – The purpose of this paper is to determine the materials cited in doctoral theses of botany, submitted to the Kuvempu University during the years 2000‐2006, with the aim of improving the existing collection development of the library.Design/methodology/approach – The study employed descriptive research design. Theses submitted for the award of Doctoral degree from 2000 to 2006 to the Department of Botany, Kuvempu University were examined. The population of the study was all the theses submitted during the periods under study. Data were extracted from title page and references given at the end of each chapter. Extracted data were analysed using statistics.Findings – The study reveals that journals are the most preferred sources of information used by the researchers in the field of botany, accounting for 74.77 per cent of total citations, although citations from books, proceedings, theses, reports and patents are also found. It is also observed those researchers are not taking much advantage of in...

Electrochemical bulk synthesis of Fe3O4 and α‐Fe2O3 nanoparticles and its ZnCoαFe2O3 composite thin films for corrosion protection

Abstract: Nanocrystalline Fe3O4 and α-Fe2O3 particles were successfully synthesized by hybrid electrochemical-thermal method. The as-prepared compound was calcined for an hour at different temperature. The crystallite size, morphology, and chemical state of the synthesized powders were characterized by powder XRD, TG-DTA, XPS, SEM/EDAX, TEM, FT-IR, and UV–Vis spectral techniques. Rietveld refinement of X-ray data of the calcined compound exhibits rhombohedral (hematite) structure with space group of R3c (No. 167). The thermal behavior of as-prepared compound was examined. Scanning electron photomicrographs show uniform, randomly oriented hexagonal and spherical like morphology and EDAX measurement showed its chemical composition. The TEM result revealed that the particle morphology was hexagonal with spherical in nature and sizes were in the order of 40–60 nm in diameter and 120–200 nm in length. The absorption and blue shift were noticed in UV–Vis absorption spectra and the band gaps were found to be 4.22–4.29 eV. The electrochemically generated Fe3O4 and α-Fe2O3 nanoparticles were used to fabricate ZnCoαFe2O3 composite thin films and its corrosion behavior was analyzed by anodic polarization, Tafel extrapolation, and electrochemical impedance spectroscopy (EIS). The results indicate that the ZnCoαFe2O3 composite thin films have potential applications to corrosion protection.