Kuvempu University

About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.

An efficient Bi(NO3)3 · 5H2O catalyzed multi component one-pot synthesis of novel Naphthyridines

Abstract: An efficient and environmentally friendly multicomponent synthesis of substituted 1,8-naphthyridines catalyzed by bismuth(III) nitrate pentahydrate [Bi(NO3)3 · 5H2O] under solvent-free microwave irradiation is described. This procedure has such advantages as short reaction time, high yields, and simple workup. The catalyst could be reused several times, keeping its initial activity recycled reactions.

Cytotoxic activity of methanolic extracts of solanum erianthum d. don

Abstract: Objective: The study was aimed to evaluate cytotoxic activity of the methanolic extracts of Solanum erianthum on HeLa, HepG-2 and MCF-7 cell lines. Methods: The percentage viability of the cell lines were carried out using trypan blue dye exclusion method and the cytotoxicity of the extracts was evaluated by MTT assay . Result: Solanum erianthum leaf and fruit extract showed significant cytotoxic activity on the tested cell lines with IC 50 values ranging from 111.67 to 385 µg mL -1 . Fruit extract showed potent cytotoxic activity on MCF-7 (IC 50 111.67 µgmL -1 ), followed by leaf extract (IC 50 150.50 µgmL -1 )on HeLa cell line using MTT assay. Cell viability assay showed that fruit extract was very active on MCF-7 and leaf extract was effective against HeLa. Conclusion: The experiment performed reveals that Solanum erianthum can be used in development of anticancer drug.

Radiation dose from dissolved radon in potable waters of the Bangalore environment, South India

Abstract: Potable waters from various locations of the Bangalore environment were investigated for their 222Rn concentrations by the emanometry method. About 94 groundwater (borewell) samples were analysed for 222Rn concentrations and found to vary in the range 5.3–283.4 Bq L−1 with a mean value of 87 Bq L−1. Frequency distribution showed the 222Rn concentration in a large number of samples in the range of 0–50 Bq L−1. From the measured concentrations, the effective doses (lung and stomach) for the population of the region were estimated. The effective dose was found to vary from 42.6 to 2280.2 µSv y−1 with a mean value 702.5 µSv y−1. The effect of boiling of water showed a drastic reduction in the 222Rn concentration. The results of the present investigation are systematically analysed, compared with the literature values and discussed.

Fe(II) Complexes Containing Bioactive Ligands: Synthesis, DNA Binding, and Cleavage Studies

Abstract: The two Fe(II) complexes of fused aromatic N and S containing ligands of the type [Fe(HMq)3] (PF6)2 [complex (1)] and [Fe(HSeq)3] (PF6)2 [complex (2)] (where HMq = 2-mercapto-4-methylquinoline and HSeq = 2-seleno-4-methylquinoline) were synthesized and structurally characterized. The DNA binding property of the complexes with calf thymus DNA has been investigated using absorption spectra, viscosity measurements, as well as thermal denaturation experiments. Intrinsic binding constant Kb has been estimated at room temperature. The absorption spectral studies indicate that the complexes intercalate between the base pairs of the CT-DNA tightly with intrinsic DNA binding constant of 1.9 × 106 M−1 for complex (1) and 2.5 × 106 M−1 for complex (2) in 5 mM Tris-HCl/50 mM NaCl buffer at pH 7.2, respectively. Detailed analysis revealed that the metal complexes intercalates into the DNA base stack as intercalator. The oxidative cleavage activity of the complexes (1) and (2) were studied by using gel electrophoresis ...

Preparation and Kinetic Considerations for the Dissolution of Cr‐substituted Iron Oxides in Reductive‐complexing Formulations

Abstract: The dissolution rate coefficients of Cr-substituted (0-20 at.% Cr) iron oxides viz. hematite and magnetite were determined by using an inverse cubic rate (ICR) law applicable for spherical particles as well as by a general kinetic equation (GKE) applicable for polydispersed particles. An attempt is made to compare both the treatments for different kinds of dissolution profiles obtained by employing oxides with narrow particle size distribution in V(II)-EDTA and citric acid-EDTA-ascorbic acid formulations at 353±5K. The dissolution profiles could be classified into three types based on the nature of oxide and formulations. It is observed that both ICR and GKE treat the dissolution course as a function of decrease in fraction of undissolved mass, m/m0. The dissolution rate coefficients determined by ICR and GKE have shown the similar trend of decrease with increasing Cr content of the oxides and was ascribed to lattice stabilization. Les coefficients de vitesse de dissolution des oxydes de fer substitues par du Cr (0-20 % de Cr), a savoir l'hematite et la magnetite, ont ete determines a l'aide de la loi de « vitesse cubique inverse » (ICR) applicable aux particules spheriques ainsi que d'une « equation cinetique generale » (GKE) applicable aux particules polydispersees. On tente de comparer ces deux approches pour differentes sortes de profils de dissolution obtenus avec des oxydes a distribution de tailles de particules etroite dans les formulations de V(II)-EDTA et d'acide citrique-EDTA-acide ascorbique a 353±5K. Les profils de dissolution pourraient se classer en trois categories selon la nature de l'oxyde et les formulations. On observe que les methodes ICR et GKE traitent le processus de dissolution comme une fonction de la diminution de la fraction de matiere non dissoute, m/m0. Les coefficients de vitesse de dissolution determines par l'ICR et la GKE montrent la meme tendance a la diminution avec l'augmentation de la teneur en Cr des oxydes, ce qui est impute a une stabilisation du reseau.