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Institution

Kuvempu University

EducationShimoga, India
About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.


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Journal ArticleDOI
TL;DR: The results indicate that Leea indica was a promising antioxidant and anticancer agent for DU-145 and PC-3 human prostate cancer cell lines, however, further studies are needed to conclude its therapeutic use.
Abstract: Background To determine the phytochemical constituents, antioxidant, and anticancer activities of Leea indica leaf extracts on DU-145 and PC-3 human prostate cancer cell lines. Methods Leaf sample was subjected to Soxhlet extraction method with increasing polarity of solvents, namely, chloroform, ethyl acetate, methanol, ethanol, and aqueous. Phytochemical screening was done using different biochemical tests. Quantitative analysis for phenol was determined by Folin–Ciocalteu reagent method. The antioxidant activity was tested using 2,2-diphenyl-1-picrylhydrazyl, ferric ion reducing power assay, and phosphomolybdenum assay. In vitro anticancer activity on DU-145 and PC-3 human prostate cancer cell lines was evaluated by (3-(4, 5-dimethyl thiazole-2yl)-2, 5-diphenyl tetrazolium bromide) MTT assay. Results Phytochemical screening confirmed the presence of phyto-constituents like alkaloids, flavonoids, glycosides, phenols, lignins, saponins, sterols, tannins, anthraquinone, and reducing sugar. Methanol and ethanol extracts exhibited higher phenolic content as compare to aqueous extract. Antioxidant capacities were shown highest in methanol and ethanol extracts based on the test performed. The methanol and ethanol leaf extracts were found to be selectively cytotoxic in vitro to (DU-145 and PC-3) prostate cancer cell lines with IC 50 values 529.44±42.07μg/mL and 677.11±37.01μg/mL for DU-145 and 547.55±33.52μg/mL and 631.99±50.24μg/mL for PC-3 respectively, while it had no cytotoxic effect on normal mice embryo fibroblast cells. Conclusion The results indicate that Leea indica was a promising antioxidant and anticancer agent for DU-145 and PC-3 human prostate cancer cell lines. However, further studies are needed to conclude its therapeutic use.

78 citations

Journal ArticleDOI
TL;DR: In this article, the SSNTD-based measurements of radon/thoron and their progeny were made in about 200 dwellings of the Mysore city for one year and the detector used at each house was fixed 2 m above the ground-floor.

78 citations

Journal ArticleDOI
01 Apr 2019-Heliyon
TL;DR: The noteworthy finding is that the thermal conductivity is greater in hybrid nanofluid than that of a regular nan ofluid in the presence of specified factors.

78 citations

Journal ArticleDOI
TL;DR: Significantly more isolates were obtained during the winter season than monsoon and summer seasons and Alternaria, Chaetomium, Fusarium, Colletotrichum, Cladosporium, Penicillium, Phyllosticta and Xylaria were the most frequently isolated.

78 citations

Journal ArticleDOI
TL;DR: In this paper, a canonical structure of the $A$ map is introduced, which enables us to investigate whether the dynamics is completely positive or not completely positive (NCP) in an elegant way and, hence, subsumes the basic results on open-system dynamics.
Abstract: Dynamical $A$ and $B$ maps have been employed extensively by Sudarshan and co-workers to investigate open-system evolution of quantum systems. A canonical structure of the $A$ map is introduced here. It is shown that this canonical $A$ map enables us to investigate whether the dynamics is completely positive (CP) or not completely positive (NCP) in an elegant way and, hence, it subsumes the basic results on open-system dynamics. Identifying memory effects in open-system evolution is gaining increasing importance recently and, here, a criterion of non-Markovianity, based on the relative entropy of the dynamical state is proposed. The relative entropy difference of the dynamical system serves as a complementary characterization---though not related directly---to the fidelity difference criterion proposed recently. Three typical examples of open-system evolution of a qubit, prepared initially in a correlated state with another qubit (environment), and evolving jointly under a specific unitary dynamics---which corresponds to a NCP dynamical map---are investigated by employing both the relative entropy difference and fidelity difference tests of non-Markovianity. The two-qubit initial states are chosen to be (i) a pure entangled state, (ii) the Werner state, which exemplifies both entangled and separable states of qubits, depending on a real parameter, and (iii) a separable mixed state. Both the relative entropy and fidelity criteria offer a nice display of how non-Markovianity manifests itself in all three examples.

77 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20238
202224
2021214
2020189
2019139
2018135