Kuvempu University

About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.

Electrodeposition and corrosion behavior of Zn–Ni and Zn–Ni–Fe 2 O 3 coatings

Abstract: A thin film of Zn–Ni–Fe2O3 on steel substrates was prepared by electrodeposition technique using Zn–Ni alloy plating solution with nano-sized Fe2O3 particles The cathodic polarization and cyclic voltammetry techniques were used to explain deposition process The corrosion behavior of deposits was evaluated by polarization and impedance studies Scanning electron microscope (SEM) images were used to study the surface morphology of coating The grain size and amount of Fe2O3 particles present in composite coating were measured by X-ray diffraction pattern (XRD) and energy dispersive X-ray diffraction spectrometer (EDS), respectively

Antitumor activity of 4-amino and 8-methyl-4-(3diethylamino propylamino)pyrimido[4′,5′:4,5]thieno (2,3-b) quinolines

Abstract: The interaction of 4-aminopyrimido [4′,5′:4,5] thieno (2,3-b) quinoline and 8-methyl-4-(3-diethylaminopropylamino) pyrimido [4′,5′:4,5] thieno (2,3-b) quinoline with DNA was studied by UV–Vis and fluorescence spectrophotometry as well as by hydrodynamic methods. On binding to DNA, the absorption spectra underwent bathochromic and hypochromic shifts and the fluorescence was quenched. These compounds are able to bind to DNA with an affinity of about 106 M−1 for calf thymus DNA at ionic strength 0.01 M and their intercalating characteristic (lengthening of the DNA) depends upon the length of the chain. Binding to the GC-rich DNA of Micrococcus lysodeikticus was stronger than the binding to calf thymus DNA at ionic strength 0.01 M. The cytotoxicities of these compounds on leukemia HL-60, melanoma B16F10 and neuro 2a cells are quite similar and inhibition (IC50) is in the range of 0.992–3.968 μM. The anticancer efficacy against B16 melanoma, has provided evidence of major antitumor activity for 8-methyl-4-(3diethylaminopropylamino) pyrimido [4′,5′:4,5] thieno(2,3-b)quinoline. Single or multiple intraperitonial (i.p) doses of drug proved high level activity against the subcutaneous (s.c) grafted B16 melanoma, significantly increasing survival (p<0.001) and inhibiting tumor growth (T/C of 4%). This study offers a new intercalation functional group to DNA – targeted drug design.

Nonlinear three-dimensional stretched flow of an Oldroyd-B fluid with convective condition, thermal radiation, and mixed convection

Abstract: The effect of non-linear convection in a laminar three-dimensional Oldroyd-B fluid flow is addressed. The heat transfer phenomenon is explored by considering the non-linear thermal radiation and heat generation/absorption. The boundary layer assumptions are taken into account to govern the mathematical model of the flow analysis. Some suitable similarity variables are introduced to transform the partial differential equations into ordinary differential systems. The Runge-Kutta-Fehlberg fourth- and fifth-order techniques with the shooting method are used to obtain the solutions of the dimensionless velocities and temperature. The effects of various physical parameters on the fluid velocities and temperature are plotted and examined. A comparison with the exact and homotopy perturbation solutions is made for the viscous fluid case, and an excellent match is noted. The numerical values of the wall shear stresses and the heat transfer rate at the wall are tabulated and investigated. The enhancement in the values of the Deborah number shows a reverse behavior on the liquid velocities. The results show that the temperature and the thermal boundary layer are reduced when the non-linear convection parameter increases. The values of the Nusselt number are higher in the non-linear radiation situation than those in the linear radiation situation.