Kuvempu University

About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.

Influence of additive on nanocrystalline, bright Zn–Fe alloy electrodeposition and its properties

Abstract: The nanocrystalline, bright Zn–Fe alloy electrodeposit was prepared by using additive, condensation product of veratraldehyde and valine (VV). Scanning electron microscopy (SEM) and X-ray diffraction (XRD) analysis in the presence of an additive showed nanocrystalline nature of deposit. These studies also revealed the change in surface morphology, phase composition and orientation of coating. The additive, increases faradaic efficiency and throwing power of plating bath. In addition, appearance, hardness, adherence, ductility and corrosion resistance of Zn–Fe alloy deposit are also improved in the presence of the additive. Simultaneously, at different current densities both faradaic efficiency and throwing power increase to peak values, 91% and 23%, respectively, and thereafter decrease. The iron content and hardness of the bright coating change with applied current density. The lower corrosion resistance of bright Zn–Fe deposit at higher current density was reflected by more negative corrosion potential and lower impedance.

Synthesis of new 4-(2,5-dimethylpyrrol-1-yl)/4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial, antifungal and antitubercular agents

Abstract: A series of 4-(2,5-dimethylpyrrol-1-yl)/4-pyrrol-1-yl benzoic acid hydrazide analogs, some derived 1,3,4-oxadiazoles, 5-substituted-4-amino-1,2,4-triazolin-3-thione and 2,5-dimethyl pyrroles have been synthesized in good yields and structures of these compounds were established by IR, 1H NMR, 13C NMR, Mass spectral and elemental analysis. These compounds were evaluated for their preliminary in vitro antibacterial, antifungal and antitubercular activities against Mycobacterium tuberculosis H37Rv strain by broth dilution assay method. Twelve of these compounds displayed good antimicrobial activity, with a minimum inhibitory concentration (MIC) values 1–4 μg mL−1. Several compounds 4, 8d, 9, 12c–d and 12f–h exhibited good in vitro antitubercular activity with MIC values 1–2 μg mL−1. Further, some title compounds were also assessed for their cytotoxic activity (IC50) against mammalian Vero cell lines and A549 (lung adenocarcinoma) cell lines using MTT assay method. The results reveal that these compounds exhibit antitubercular activity at non-cytotoxic concentrations. Synthesis, spectral studies and antibacterial, antifungal and antitubercular activities of a novel series of pyrrole derivatives are described

Studies on synthesis and pharmacological activities of 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles and their dihydro analogues.

Abstract: 4-Amino-5-substituted aryl-3-mercapto-1,2,4-triazoles are versatile synthons for constructing various biologically active heterocycles. Starting from 4-amino-5-substituted aryl-3-mercapto-1,2,4-triazole 3a-c, a series of new 3,5-disubstituted-1,2,4-triazolo-[3,4-b]1,3,4-thiadiazoles and their 5,6-dihydrotriazolothiadiazoles were prepared. The structures of all the newly synthesized compounds have been confirmed by elemental analysis, IR,( 1)H-NMR, (13)C-NMR, and mass spectra. The antimicrobial effects of the synthesized compounds were investigated using the paper disc method. Anti-inflammatory and analgesic activities of the synthesized compounds were assessed by carrageenan-induced rat paw oedema method and by Eddy's hot plate method, respectively. Some of the compounds exhibited promising antimicrobial activities as well as moderate to good anti-inflammatory activity and analgesic activity.

Synthesis and Characterization of Endophytic Fungi, Cladosporium perangustum Mediated Silver Nanoparticles and their Antioxidant, Anticancer and Nano-toxicological Study

Abstract: In the present study, endophytic fungi, Cladosporium perangustum, water extract was used to analyze phytochemical by qualitative and GC-MS methods. Synthesis of the silver nanoparticles were characterized by UV-vis spectra, XRD, FTIR, DLS, EDX and SEM to know the biophysical properties and these were evaluated for antioxidant, anticancer and nano-toxicological studies. The endophytic fungal water extract yielded biologically important phytochemicals in qualitative method and the GC-MS yielded five different types of phytochemicals. The colour was changed to dark brown when silver nitrate incubated with C. perangustum water extract. Typical silver nanoparticle formations were confirmed using UV-visible spectra at 420 nm and were spherical shaped ranging size 30–40 nm. The CpAgNPs showed significant antioxidant activity compared with ascorbic acid and butylated hydroxytoluene in all the four methods (DPPH, scavenging activity of H2O2 and nitric oxide and reducing power). The CpAgNPs significantly reduced the viability of the MCF-7 cancer cell line and enhanced the caspase-3, caspase-7, caspase-8 and caspase-9 activities at the highest level, assumed to be CpAgNPs induce mitochondrial-mediated apoptosis. The CpAgNPs had cause cytotoxic effect on actively growing onion root tip cells by exhibiting different mechanism. But CpAgNPs had not inhibited the growth of green gram and also exhibited anti-hemolysis and heme-biocompatible activity on human blood RBCs. In all results, the study provided use of endophytic fungi C. perangustum in the synthesis of nanoparticles and their significant antioxidant, anticancer and nano-toxicological studies. The results are strong evidence to develop potential antioxidant and anticancer silver nanoparticles for commercial application.

Studies on electrodeposition of Zn–MoS2 nanocomposite coatings on mild steel and its properties

Abstract: Pure zinc and Zn–MoS2 composite coatings were prepared by electrodeposition from zinc sulfate–chloride bath containing uniformly dispersed MoS2 nanoparticles The effect of MoS2 on the deposition properties morphology, crystallographic orientation, and corrosion behavior were studied The electrokinetic properties (zeta potential) and size distribution statistics in plating bath for the particles were evaluated using dynamic light scattering experiments The Zn and Zn–MoS2 deposition process was studied by linear polarization and cyclic voltammetry Scanning electron microscopy, energy dispersive X-ray analysis, X-ray diffraction analysis, and potentiodynamic polarization measurements were used to characterize the coatings The addition of MoS2 to the electrolyte significantly changed the microstructure and crystallographic orientation of the zinc deposits and enhanced the corrosion resistance of the coatings The morphological and electrochemical properties of the zinc coatings were observed to be significantly affected by the incorporation of MoS2 particles into the zinc matrix