Kuvempu University

About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.

Miscibility studies on chitosan/hydroxypropylmethyl cellulose blend in solution by viscosity, ultrasonic velocity, density, and refractive index methods

Abstract: The miscibility studies of chitosan (CHI)/hydroxypropylmethyl cellulose (HPMC) blend in buffer solution (0.1M acetic acid + 0.2M sodium acetate) were carried out by viscosity, ultrasonic velocity, density, and refractive index methods at 30, 40, and 50°C, respectively. Using viscosity data, the interaction parameter μ and α were computed. These values revealed that the blend is miscible when the CHI content is more than 50% in the blend. The obtained results were further confirmed by ultrasonic velocity, density, and refractive index study. And also the result revealed that the change in temperature has no significant effect on the miscibility of CHI/HPMC polymer blends. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 2738–2742, 2006

Boundary layer flow past a stretching sheet with fluid-particle suspension and convective boundary condition

Abstract: The steady two-dimensional boundary layer flow of a viscous dusty fluid over a stretching sheet with the bottom surface of the sheet heated by convection from a hot fluid is considered. The governing partial differential equations are transformed into ordinary differential equations using a similarity transformation, before being solved numerically by a Runge–Kutta–Fehlberg fourth-fifth order method (RKF45 Method) with the help of MAPLE. The effects of convective Biot number, fluid particle interaction parameter, and Prandtl number on the heat transfer characteristics are discussed. It is found that the temperature of both fluid and dust phase increases with increasing Biot number. A comparative study between the previous published and present results in a limiting sense is found in an excellent agreement.

Microwave Assisted Synthesis of Some Novel Thiopyrano[2,3-b]quinolines as a New Class of Antimicrobial Agent

Abstract: A series of novel substituted thiopyrano[2,3-b]quinolines 4a–e , 5a–e , and 6a–e were prepared from substituted 3-formyl-2-mercapto quinolines 2a–e , on reaction with ethyl acetoacetate, diethyl malonate, and ethyl cyanoacetate 3a–c by microwave irradiation in the presence of piperidine. Synthesized compounds were evaluated for antimicrobial activities. Among the compounds tested, 7-chloro-2-oxo-2H-thiopyrano[2,3-b]quinoline-3-carbonitrile 6d and 7-nitro-2-oxo-2H-thiopyrano[2,3-b]quinoline-3-carbonitrile 6e were highly active against S. aureus and M. roseus.

A Bioinformatics Resource for TWEAK-Fn14 Signaling Pathway

Abstract: TNF-related weak inducer of apoptosis (TWEAK) is a new member of the TNF superfamily. It signals through TNFRSF12A, commonly known as Fn14. The TWEAK-Fn14 interaction regulates cellular activities including proliferation, migration, differentiation, apoptosis, angiogenesis, tissue remodeling and inflammation. Although TWEAK has been reported to be associated with autoimmune diseases, cancers, stroke, and kidney-related disorders, the downstream molecular events of TWEAK-Fn14 signaling are yet not available in any signaling pathway repository. In this paper, we manually compiled from the literature, in particular those reported in human systems, the downstream reactions stimulated by TWEAK-Fn14 interactions. Our manual amassment of the TWEAK-Fn14 pathway has resulted in cataloging of 46 proteins involved in various biochemical reactions and TWEAK-Fn14 induced expression of 28 genes. We have enabled the availability of data in various standard exchange formats from NetPath, a repository for signaling pathways. We believe that this composite molecular interaction pathway will enable identification of new signaling components in TWEAK signaling pathway. This in turn may lead to the identification of potential therapeutic targets in TWEAK-associated disorders.