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Institution

Kyoto University

EducationKyoto, Japan
About: Kyoto University is a education organization based out in Kyoto, Japan. It is known for research contribution in the topics: Population & Catalysis. The organization has 85837 authors who have published 217215 publications receiving 6526826 citations. The organization is also known as: Kyōto University & Kyōto daigaku.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the Thouless pump was demonstrated in a dynamically controlled optical superlattice with ultracold fermionic atoms and the topological invariance of the pumping process was analyzed.
Abstract: Charge transport in a cyclically time-modulated periodic potential, also known as a topological Thouless pump, has been realized in an ultracold gas of fermionic atoms. An electron gas in a one-dimensional periodic potential can be transported even in the absence of a voltage bias if the potential is slowly and periodically modulated in time. Remarkably, the transferred charge per cycle is sensitive only to the topology of the path in parameter space. Although this so-called Thouless charge pump was first proposed more than thirty years ago1, it has not yet been realized. Here we report the demonstration of topological Thouless pumping using ultracold fermionic atoms in a dynamically controlled optical superlattice. We observe a shift of the atomic cloud as a result of pumping, and extract the topological invariance of the pumping process from this shift. We demonstrate the topological nature of the Thouless pump by varying the topology of the pumping path and verify that the topological pump indeed works in the quantum regime by varying the speed and temperature.

535 citations

Journal ArticleDOI
TL;DR: In this paper, the authors examined the results of laboratory experiments that have provided initial constraints on the nuclear symmetry energy and on its density dependence at and somewhat below normal nuclear matter density.
Abstract: The symmetry energy contribution to the nuclear equation of state impacts various phenomena in nuclear astrophysics, nuclear structure, and nuclear reactions. Its determination is a key objective of contemporary nuclear physics, with consequences for the understanding of dense matter within neutron stars. We examine the results of laboratory experiments that have provided initial constraints on the nuclear symmetry energy and on its density dependence at and somewhat below normal nuclear matter density. Even though some of these constraints have been derived from properties of nuclei while others have been derived from the nuclear response to electroweak and hadronic probes, within experimental uncertainties-they are consistent with each other. We also examine the most frequently used theoretical models that predict the symmetry energy and its slope parameter. By comparing existing constraints on the symmetry pressure to theories, we demonstrate how contributions of three-body forces, which are essential ingredients in neutron matter models, can be determined.

535 citations

Journal ArticleDOI
TL;DR: An optimized backbone for the rapid development of a highly sensitive intramolecular fluorescence resonance energy transfer (FRET) biosensor is reported, which includes an optimized pair of fluorescent proteins and a long flexible linker ranging from 116 to 244 amino acids in length.
Abstract: We report an optimized backbone for the rapid development of a highly sensitive intramolecular fluorescence resonance energy transfer (FRET) biosensor, which includes an optimized pair of fluoresce...

535 citations

Journal ArticleDOI
TL;DR: Gold nanoparticles modified with ionic liquids based on the imidazolium cation are synthesised and Aggregation-induced color changes of the gold nanoparticles in an aqueous solution were used as an optical sensor for anions via anion exchange of ionic liquid moiety.
Abstract: The synthesis and processing of nanoparticles consisting of metallic nanocrystal cores and organic monolayer shells promise interesting technological applications. Here, we report the synthesis of gold nanoparticles modified with ionic liquids based on the imidazolium cation. Aggregation-induced color changes of the gold nanoparticles in an aqueous solution were used as an optical sensor for anions via anion exchange of ionic liquid moiety. We also demonstrated the phase transfer of the gold nanoparticles from aqueous media to ionic liquid.

535 citations

Journal ArticleDOI
TL;DR: It is shown that regulatory T (T reg) cells have a miRNA profile distinct from conventional CD4 T cells, and results suggest that T reg cell development involves Dicer-generated RNAs.
Abstract: Micro RNAs (miRNAs) regulate gene expression at the posttranscriptional level. Here we show that regulatory T (T reg) cells have a miRNA profile distinct from conventional CD4 T cells. A partial T reg cell–like miRNA profile is conferred by the enforced expression of Foxp3 and, surprisingly, by the activation of conventional CD4 T cells. Depleting miRNAs by eliminating Dicer, the RNAse III enzyme that generates functional miRNAs, reduces T reg cell numbers and results in immune pathology. Dicer facilitates, in a cell-autonomous fashion, the development of T reg cells in the thymus and the efficient induction of Foxp3 by transforming growth factor β. These results suggest that T reg cell development involves Dicer-generated RNAs.

534 citations


Authors

Showing all 86225 results

NameH-indexPapersCitations
Kari Alitalo174817114231
Ralph M. Steinman171453121518
Masayuki Yamamoto1711576123028
Karl Deisseroth160556101487
Kenji Kangawa1531117110059
Takashi Taniguchi1522141110658
Ben Zhong Tang1492007116294
Takeo Kanade147799103237
Yuji Matsuzawa143836116711
Tasuku Honjo14171288428
Kenneth M. Yamada13944672136
Y. B. Hsiung138125894278
Shuh Narumiya13759570183
Kevin P. Campbell13752160854
Junji Tojo13587884615
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023234
2022679
20218,533
20208,740
20198,050
20187,932