Kyungpook National University

About: Kyungpook National University is a education organization based out in Daegu, South Korea. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 20497 authors who have published 42107 publications receiving 834608 citations.

CMS physics technical design report: Addendum on high density QCD with heavy ions

Abstract: This report presents the capabilities of the CMS experiment to explore the rich heavy-ion physics programme offered by the CERN Large Hadron Collider (LHC). The collisions of lead nuclei at energies , will probe quark and gluon matter at unprecedented values of energy density. The prime goal of this research is to study the fundamental theory of the strong interaction ? Quantum Chromodynamics (QCD) ? in extreme conditions of temperature, density and parton momentum fraction (low-x).This report covers in detail the potential of CMS to carry out a series of representative Pb-Pb measurements. These include bulk observables, (charged hadron multiplicity, low pT inclusive hadron identified spectra and elliptic flow) which provide information on the collective properties of the system, as well as perturbative probes such as quarkonia, heavy-quarks, jets and high pT hadrons which yield tomographic information of the hottest and densest phases of the reaction.

Support vector machines for texture classification

Abstract: This paper investigates the application of support vector machines (SVMs) in texture classification. Instead of relying on an external feature extractor, the SVM receives the gray-level values of the raw pixels, as SVMs can generalize well even in high-dimensional spaces. Furthermore, it is shown that SVMs can incorporate conventional texture feature extraction methods within their own architecture, while also providing solutions to problems inherent in these methods. One-against-others decomposition is adopted to apply binary SVMs to multitexture classification, plus a neural network is used as an arbitrator to make final classifications from several one-against-others SVM outputs. Experimental results demonstrate the effectiveness of SVMs in texture classification.

Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation

Abstract: Plastics, including poly(ethylene terephthalate) (PET), possess many desirable characteristics and thus are widely used in daily life However, non-biodegradability, once thought to be an advantage offered by plastics, is causing major environmental problem Recently, a PET-degrading bacterium, Ideonella sakaiensis, was identified and suggested for possible use in degradation and/or recycling of PET However, the molecular mechanism of PET degradation is not known Here we report the crystal structure of I sakaiensis PETase (IsPETase) at 15 A resolution IsPETase has a Ser–His-Asp catalytic triad at its active site and contains an optimal substrate binding site to accommodate four monohydroxyethyl terephthalate (MHET) moieties of PET Based on structural and site-directed mutagenesis experiments, the detailed process of PET degradation into MHET, terephthalic acid, and ethylene glycol is suggested Moreover, other PETase candidates potentially having high PET-degrading activities are suggested based on phylogenetic tree analysis of 69 PETase-like proteins

Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapy.

Abstract: Tumor targetability and site-specific drug release of therapeutic nanoparticles are key factors for effective cancer therapy. In this study, poly(ethylene glycol) (PEG)-conjugated hyaluronic acid nanoparticles (P-HA-NPs) were investigated as carriers for anticancer drugs including doxorubicin and camptothecin (CPT). P-HA-NPs were internalized into cancer cells (SCC7 and MDA-MB-231) via receptor-mediated endocytosis, but were rarely taken up by normal fibroblasts (NIH-3T3). During in vitro drug release tests, P-HA-NPs rapidly released drugs when incubated with cancer cells, extracts of tumor tissues, or the enzyme Hyal-1, which is abundant in the intracellular compartments of cancer cells. CPT-loaded P-HA-NPs (CPT-P-HA-NPs) showed dose-dependent cytotoxicity to cancer cells (MDA-MB-231, SCC7, and HCT 116) and significantly lower cytotoxicity against normal fibroblasts (NIH-3T3) than free CPT. Unexpectedly, high concentrations of CPT-P-HA-NPs demonstrated greater cytotoxicity to cancer cells than free CPT. ...

Carbon-doped TiO2 photocatalyst synthesized without using an external carbon precursor and the visible light activity

Abstract: Carbon-doped TiO 2 (C-TiO 2 ) was successfully prepared from a conventional sol–gel synthesis without using external carbon precursors whereas all the previous reports on the synthesis of C-TiO 2 utilized them. The carbons contained in titanium alkoxide precursor could be incorporated into the lattice of TiO 2 with creating mid-bandgap electronic states through the controlled calcination. The level of carbon doping was changed sensitively depending on the calcination temperature, which was verified by UV–visible diffuse reflectance spectroscopy and X-ray photoelectron spectroscopy. The charge pair generation/recombination in C-TiO 2 was compared under visible and UV light through a time-resolved diffuse reflectance spectroscopy study, which suggested the presence of midgap energy levels induced by the incorporation of carbon dopants. The carbon doping was maximal when the calcination temperature was around 200–250 °C and hindered at higher temperatures. The visible light activities of the prepared TiO 2 samples for the conversion of 4-chlorophenol and iodide were also strongly dependent on the calcination temperature and maximized at around 250 °C. This study implies that the carbon doping in TiO 2 can be obtained even unintentionally in the conventional sol–gel synthesis.