Showing papers by "Kyushu University published in 1977"
512 citations
TL;DR: SEP, judged by the present criteria, was shown to be useful as a complementary diagnostic aid in localizing the sites of lesions in sensory pathways and in evaluating sensory function, especially when used in combination with clinical symptomatology.
287 citations
TL;DR: The results indicate that “serum-sickness” antibodies react with a common disaccharide moiety of non-reducing end of the both glycosphingolipids.
179 citations
176 citations
148 citations
TL;DR: Hydorgenation of phytosterols is a novel approach to enhance their hypocholesterolemic activities without influencing the relative safety of the initial sterols.
Abstract: The hypocholesterolemic activity of beta-sitosterol and its hydrogenated product, beta-sitostanol (dihydrositosterol or stigmastanol) has been compared in young male rats. When cholesterol was included in the diet, sitostanol consistently exhibited significantly greater hypocholesterolemic activity than sitosterol. There were no apparent differences in the effects of the sterol and the stanol on the concentration of liver cholesterol and triglyceride. Increases in plasma triglyceride due to feeding sitosterol were not observed with sitostanol. Incorporation of dietary sitostanol into plasma, liver and other tissues was always negligible, and thus this stanol was almost completely recovered in feces, while there was considerable deposition of sitosterol (mean fecal recovery being 85% to 92%). The increase in fecal output of dietary cholesterol was significantly greater with the stanol than with sterol. There was no demonstrable negative effect on growth and weight of major visceral tissues in rats fed the sterol as well as the stanol. These observations together with those reported previously indicate that hydorgenation of phytosterols is a novel approach to enhance their hypocholesterolemic activities without influencing the relative safety of the initial sterols.
145 citations
TL;DR: Results indicate that thednaA gene product is required for the replication of pSC101 DNA.
Abstract: Replication of pSC101 was analyzed by using DNA-DNA hybridization and alkaline sucrose gradient centrifugation. Mutants of thednaA gene were tested for their capacity to replicate pSC101 DNA at a non-permissive temperature. Only a small amount of radioactive precursor was incorporated into pSC101 DNA indnaA mutants at 42°C whereas active incorporation into plasmid DNA took place indnaA
+ strains under the same conditions. The effect of thednaA mutation was grater on plasmid DNA synthesis than on host chromosomal DNA synthesis. The numbers of copies of pSC101 per chromosome in wild type anddnaA strains, grown at 30°C, were about 8 and 2, respectively. These results indicate that thednaA gene product is required for the replication of pSC101 DNA.
123 citations
TL;DR: In this article, the influence of diffuser geometries and flow inlet conditions on the critical flow angle for reverse flow was examined, and the results were presented in graphs.
Abstract: The authors’ preceding analysis on centrifugal vaneless diffusers is used to examine the influences of diffuser geometries and of flow inlet conditions on the critical flow angle for reverse flow, and the results are presented in graphs. The diffuser width to radius ratio, the inlet Mach number, and the distortion of the inlet velocity distribution have significant influences on the critical flow angle, while the Reynolds number and the boundary layer thickness at the inlet have minor influences.
110 citations
109 citations
TL;DR: In this article, the breakdown mechanisms in a non-uniform field gap with a free conducting sphere can be classified into four kinds with regard to the particle movement and the occurring position of breakdown.
101 citations
TL;DR: A high yield of viable single cells was attained from isolated pancreatic islets of adult rat by the sequential treatment with EDTA and Dispase, and excellent preservation of free islet cells dissociated with EDta-Dispase was demonstrated morphologically by light and electron microscopy.
Abstract: A high yield of viable single cells was attained from isolated pancreatic islets of adult rat by the sequential treatment with EDTA and Dispase. The percentage of single cells was consistently higher with EDTA-Dispase in comparison with EDTAtrypsin treatment, being 65.8±7.9% and 36.0±5.4% respectively, when more than 90% of total islet cells were viable. Excellent preservation of free islet cells dissociated with EDTA-Dispase was demonstrated morphologically by light and electron microscopy.The secretory response of dissociated B cells to glucose was stabilized earlier with EDTA-Dispase than with EDTA-trypsin treatment. The amount of insulin released into the medium was proportional to the number of cells inoculated, thus permitting the quantitative analysis of B-cell function in vitro.
TL;DR: In this paper, a new crown ether, 4′-picrylaminobenzo-15-crown-5 (HL), was used for the extraction of alkali metal ions.
Abstract: The extraction study of alkali metal ions was made with a new type of crown ether, 4′-picrylaminobenzo-15-crown-5 (HL). Upon dissociation in alkaline medium orange-colored HL gives blood-red anion, L−, and extracts selectively K+ (and to a lesser extent Rb+) ion into chloroform as a colored complex of composition ML·HL. A colorimetric determination of 10 - 400 ppm K+ in the presence of < 2000 ppm Na+ was possible using this new crown ether reagent.
TL;DR: In this article, an unsteady lifting surface theory for a rotating subsonic annular cascade has been developed to predict the blade forces and the acoustic power generation caused by interaction of blades with inlet distortions or wakes.
15 Jun 1977
TL;DR: In this paper, critical micelle concentrations and the solubilization toward dyestuff yellow OB in aqueous solutions of mixed polyoxyethylene-type nonionic and anionic surfactants at 30°C were measured.
Abstract: Critical micelle concentrations (CMC) and the solubilization toward dyestuff yellow OB in aqueous solutions of mixed polyoxyethylene-type nonionic and anionic surfactants at 30°C were measured. As for the CMC, the stabilization of the mixed micelles relating to polyoxyethylene chains was suggested by application of the pseudo-phase-separation model. Concerning solubilization, the same measurements were also performed for various other surfactant mixed systems, and we defined the solubilizing power of the mixed surfactant solution and the ratio of this quantity to that in the additivity law. Solubilization in the system of mixed polyoxyethylene-type nonionic and anionic surfactants showed a specific behavior as compared with the other systems. From the CMC and solubilization studies, we proposed the model concerning the mixed micelles of polyoxyethylene-type nonionic and anionic surfactants. In the model, polyoxyethylene chains in the mixed micelle have an attracting interaction with anionic head groups, and the interaction is enhanced by the formation of a hydrocarbon core. This status is different from that in free polyethylene glycol and surfactant systems.
TL;DR: Analysis of temperature sensitive growth mutants of E. coli for mutant strains showing longer mRNA half-life indicated that the stability of pulse-labeled RNA as well as of tryptophan (trp) mRNA increased four to seven fold over its parental strain at 42° C.
Abstract: We have screened 897 temperature sensitive growth mutants of E. coli for mutant strains showing longer mRNA half-life. The fate of pulse-labelled RNA was examined at 42 degrees C after cessation of RNA synthesis and with prior exposure to nonpermissive temperature (42 degrees C). Eight stains showed altered turnover of RNA (presumably mRNA), and further analysis on mutant strain JE15144 indicated that the stability of pulse-labeled RNA as well as of tryptophan (trp) mRNA increased four to seven fold over its parental strain at 42 degrees C. At 4 min or 10 min after addition of rifampicin, some 70 to 80% of polyribosome in the growing cells could still be conserved in JE15144 cultured at the nonpermissive temperature while little, if any, polyribosomes remained in its parental strain (PA3092) under the same condition. Two generation times were required for complete stoppage of growth of this mutant strain after shifting to 42 degrees C, and protein synthesis continued at a significant, but slightly reduced, rate at 42 degrees C. However, functional decay of mRNA in the mutant strain, with respect to the capacity for producing peptides, appeared to be similar to the parent strain, with half-lives of 3.5 min in PA3092 and 4.7 min in JE15144.
TL;DR: In contrast to the PCBs, which were found far more in the adipose tissue than in the liver, PCDFs occurred in very similar concentrations in these two types of tissue.
TL;DR: In this article, the free energy difference of the ionic head group of the surfactant between a bulk and a mixed micellar state is much greater for anionic nonionic than for cationic-nonionic mixtures.
TL;DR: It is concluded that the characteristic of aggression induced by raphe lesions is different in many respects from that induced by p-chlorophenylalanine administration, olfactory bulbectomy and septal lesions.
TL;DR: The ultrastructure of six distinct antennal sensory organs of the cockroach, Periplaneta americana, has been examined and appears to function in contact chemoreception and olfaction.
TL;DR: In protection against Candida infection, non‐immune phagocytosis and T cell‐mediated immunity appear to be required at the early and late stages of infection, respectively.
Abstract: Live organisms (cfu) of Candida albicans per organ were counted 1 hr and 1 to 20 days after an intravenous inoculation into various groups of mice which had distinct levels of immunologic or non-immunologic defense mechanisms. a) The number of cfu in the liver decreased progressively in normal mice, but those in the kidney maintained a constant level during the observation period. b) The number of cfu in the liver decreased progressively also in nude mice. In their kidneys, however, cfu increased progressively at a late stage of infection. c) In lethally irradiated AKR of nude mice in which phagocyte functions were severely depressed, the number of cfu increased progressively in both liver and kidney from the initial stage of infection. d) In immunized AKR mice, growth of C. albicans was suppressed at late stages of infection. Such protective immunity could be transferred partly with immune lymphoid cells but not with hyperimmune serum in the experimental system employed. In protection against candida infection, non-immune phagocytosis and T cell-mediated immunity appear to be required at the early and late stages of infection, respectively.
TL;DR: In this paper, the authors measured the ionization cross sections by electron impact for 19 elements with atomic number in the range Z=13\ensuremath{-}92, $L$- and $M$-shell ionisation cross sections for nine and two heavier elements, respectively, in the energy range 70-270 MeV.
Abstract: We have measured $K$-shell ionization cross sections by electron impact for 19 elements with atomic number in the range $Z=13\ensuremath{-}92$, $L$- and $M$-shell ionization cross sections for nine and two heavier elements, respectively, in the energy range 70-270 MeV. The results on the $K$-shell ionization were compared with the predictions from the revised Kolbenstvedt theory and the plane-wave Born approximation calculation by Davidovi\ifmmode \acute{c}\else \'{c}\fi{} and Moiseiwitsch, and good agreements were obtained. The $L$- and $M$-shell ionization cross sections were also compared with the predictions from the Kolbenstvedt theory using photoeffect cross sections for these shells and good agreements were obtained, although there is some ambiguity in the photoeffect cross section used in the estimation. The $K$-shell ionization cross sections, together with other experimental results, were represented in a good scaled form based on the revised Kolbenstvedt theory.
TL;DR: A case of intraventricular cavernous hemangioma is reported, with a review of the literature, especially that dealing with angiography of intracerebral lesions.
Abstract: A case of intraventricular cavernous hemangioma is reported, with a review of the literature, especially that dealing with angiography of intracerebral lesions. Dense venous poolings and a localized area of venous stain were observed in this case.
TL;DR: The results suggest that the diltiazem hydrochloride is a slow channel inhibitor, and its clinical implication is discussed in terms of antiarrhythmic activity.
Abstract: The effect of diltiazem hydrochloride (CRD-401), a coronary vasodilator, was investigated in isolated perfused canine ventricular muscles and Purkinje fibers using microelectrodes. The drug at a concentration of 1μg/ml lowered the level of action potential plateau and shortened the duration in both ventricular and Purkinje fibers without change in maximum rate of rise (Vmax) or resting potential. Contractile tension of ventricular muscle was markedly decreased with shortening of plateau. With higher drug concentration (5μg/ml), Vmax in both ventricular muscle and Purkinje fiber decreased about 20% without change in resting potential, and the effect on repolarization became more marked. The drug blocked spontaneous firing which appeared in depolarized Purkinje fibers and abolished the automaticity elicited in electrically depolarized ventricular muscles. Input resistance of ventricular muscle, measured by small, hyperpolarizing short pulses, was not changed appreciably by the drug; suggesting no change in potassium conductance. These results suggest that the drug is a slow channel inhibitor, and its clinical implication is discussed in terms of antiarrhythmic acitivty.
TL;DR: The rate of dissolu tion of solid lime in to liquid slag was determined from the decrease of diameter of the lime cylillder rotated ill CaOSiO.-AI, 0 3 or FcOCa OSi02 slag as mentioned in this paper.
Abstract: The rate of dissolu tion of solid lime in to liquid slag was determinedfrom the decrease of diameter of the lime cylillder rotated ill CaOSiO.-AI ,0 3 or FcOCa OSi02 slag. T he j)enetration of the slag to the solid phase and the distribution of componellts in liquid slag alijacent into the solidliquid inter.face were examined by the E. P.M.A. technique. The rate of dissolution increased with temperatllre and with rotating s/)eed of Ihe ~ylinder, sllptJorling the assumption that the diffilsioll of calcizlln through a slag phase boulldary layer would be the rate-determining step . The dissolution rate into the slag containing FeO was several times greater than thai into slag without FeO , because q{ the differences ill /)hysi cal /)roperties of slag and ill the morphology of 2CaO · Si02 formation . S lag componellts jJellelrated into solid lime Wire maillly AI, O , and FeO, alld the SiO, content was very little . This can be inter/lTeled by the formation of AI , O \" or FeO rich slag layer betweell solid lime alld 2CaO· SiO ,jilm.
TL;DR: The results indicate that fluid in the suprachoroid may leave the eye by flow through the loose connective tissue around the blood vessels and nerves and also through the scleral substance.
TL;DR: In this paper, a new analytical treatment is proposed for estimating the sound pressure level of turbulent noise radiated from low pressure axial flow fans, and a physical model which is very simple but reasonable is introduced to explain the turbulent noise generation originating from the vortex shedding from rotor blades.
TL;DR: The ability of pullulans S-1 to produce pullulan varied considerably with the initial pH as mentioned in this paper, i.e. initial pH, the fall of pH during culture, and the agitation rate greatly influenced the ability of the organism to elaborate pullulane.
Abstract: The capability of Aureobasidium pullulans S-1 to produce pullulan varied considerably with the initial pH; that is, pullulan was hardly elaborated with initial pH 2 ~ 2.5, and the organism converted ca. 50% (by shaking culture) or ca. 60% (with jar fermenter) of consumed sugar into pullulan with initial pH 6.0. Initial pH, the fall of pH during culture, and the agitation rate greatly influenced the ability of the organism to elaborate pullulan.