Kyushu University

About: Kyushu University is a education organization based out in Fukuoka, Japan. It is known for research contribution in the topics: Population & Catalysis. The organization has 68284 authors who have published 135190 publications receiving 3055928 citations. The organization is also known as: Kyūshū Daigaku.

GETDB, a database compiling expression patterns and molecular locations of a collection of gal4 enhancer traps

Abstract: Shigeo Hayashi,* Kei Ito, Yukiko Sado, Misako Taniguchi, Ai Akimoto, Hiroko Takeuchi, Toshiro Aigaki, Fumio Matsuzaki, Hideki Nakagoshi, Teiichi Tanimura, Ryu Ueda, Tadashi Uemura, Motojiro Yoshihara, and Satoshi Goto National Institute of Genetics, Mishima, Shizuoka-ken, Japan Department of Genetics, Graduate University for Advanced Studies, Mishima, Shizuoka-ken, Japan Riken Center for Developmental Biology, Kobe, Hyogo, Japan National Institute for Basic Biology Myodaiji, Okazaki, Aichi, Japan Department of Biology, Tokyo Metropolitan University, Tokyo, Japan Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Japan Okayama University Graduate School of Natural Science and Technology, Okayama, Japan Department of Biology, Graduate School of Sciences, Kyushu University, Ropponmatsu, Fukuoka, Japan Mitsubishi Kagaku Institute of Life Sciences, Tokyo, Japan Laboratory of Molecular Genetics, Institute for Virus Research, Kyoto University, Kyoto, Japan Center for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

The General rules for recording endoscopic findings on esophageal varices

Abstract: The Japanese Research Society for Portal Hypertension proposes the following General Rule for Recording Findings on Esophageal Varices obtained by fiberoptic endoscopy. This proposal is based on an agreement of the members, reached on the 12th Annual Meeting of the Society held on the 28th day of June, 1979 in Osaka. These rules are applicable only for recordings on esophageal varices obtained by fiberoptic endoscopy; they do not apply in recording gastric varices. Endoscopic diagnoses are to be made by inspection with the naked eye; photographs taken during the examination are not to be used as the basis for classification. Findings are to be classified into four main categories, i.e. Fundamental Color, Red Color Sign, Form, and Location.

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Abstract: Cysteine hydropersulfide (CysSSH) occurs in abundant quantities in various organisms, yet little is known about its biosynthesis and physiological functions. Extensive persulfide formation is apparent in cysteine-containing proteins in Escherichia coli and mammalian cells and is believed to result from post-translational processes involving hydrogen sulfide-related chemistry. Here we demonstrate effective CysSSH synthesis from the substrate L-cysteine, a reaction catalyzed by prokaryotic and mammalian cysteinyl-tRNA synthetases (CARSs). Targeted disruption of the genes encoding mitochondrial CARSs in mice and human cells shows that CARSs have a crucial role in endogenous CysSSH production and suggests that these enzymes serve as the principal cysteine persulfide synthases in vivo. CARSs also catalyze co-translational cysteine polysulfidation and are involved in the regulation of mitochondrial biogenesis and bioenergetics. Investigating CARS-dependent persulfide production may thus clarify aberrant redox signaling in physiological and pathophysiological conditions, and suggest therapeutic targets based on oxidative stress and mitochondrial dysfunction.

Japan Pancreatic Cancer Registry; 30th year anniversary: Japan Pancreas Society.

Abstract: ObjectivesSince 1981, the Japan Pancreas Society has been hosting a nationwide pancreatic cancer registry. To commemorate its 30th anniversary, we review its history and latest achievement.MethodsDuring 3 decades, more than 350 leading institutions in Japan contributed voluntarily to register and pe