Institution
La Trobe University
Education•Melbourne, Victoria, Australia•
About: La Trobe University is a education organization based out in Melbourne, Victoria, Australia. It is known for research contribution in the topics: Population & Health care. The organization has 13370 authors who have published 41291 publications receiving 1138269 citations. The organization is also known as: LaTrobe University & LTU.
Papers published on a yearly basis
Papers
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TL;DR: New hypotheses for this condition are proposed, which focus on the potential role of tenocytes, mechanosensitive and chemosensitive receptors, the role of ion channels in nociception and pain and central mechanisms associated with load and threat monitoring.
Abstract: Tendon pain remains an enigma. Many clinical features are consistent with tissue disruption—the pain is localised, persistent and specifically associated with tendon loading, whereas others are not—investigations do not always match symptoms and painless tendons can be catastrophically degenerated. As such, the question ‘what causes a tendon to be painful?’ remains unanswered. Without a proper understanding of the mechanism behind tendon pain, it is no surprise that treatments are often ineffective. Tendon pain certainly serves to protect the area—this is a defining characteristic of pain—and there is often a plausible nociceptive contributor. However, the problem of tendon pain is that the relation between pain and evidence of tissue disruption is variable. The investigation into mechanisms for tendon pain should extend beyond local tissue changes and include peripheral and central mechanisms of nociception modulation. This review integrates recent discoveries in diverse fields such as histology, physiology and neuroscience with clinical insight to present a current state of the art in tendon pain. New hypotheses for this condition are proposed, which focus on the potential role of tenocytes, mechanosensitive and chemosensitive receptors, the role of ion channels in nociception and pain and central mechanisms associated with load and threat monitoring.
220 citations
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TL;DR: There is a need for further research of more rigorous methodological quality, including greater consensus regarding standards for reporting of electromyographic parameters, to evaluate the literature pertaining to the effect of foot posture, foot orthoses and footwear on lower limb muscle activity during walking and running.
220 citations
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TL;DR: The purification of the enzyme from T. selenatis grown anaerobically with selenate is described, constituting the first description of a selenATE reductase, which represents a new class of enzymes.
220 citations
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TL;DR: Another Wolbachia infection is described in D. simulans that does not cause cytoplasmic incompatibility and may represent an evolutionary outcome of interactions between Wolbachian infections and their hosts.
Abstract: Microbes of the genus Wolbachia are transmitted by their hosts via the maternal parent and are responsible for cytoplasmic incompatibility among insect populations. This phenomenon can result in Wolbachia spreading through natural populations as previously demonstrated in Drosophila simulans. Here we describe another Wolbachia infection in D. simulans that does not cause cytoplasmic incompatibility. This is a property of the Wolbachia rather than the nuclear background. The infection occurs at a low frequency in natural populations from eastern Australia. The infection shows perfect maternal transmission in the field and does not cause any detectable deleterious effects on its host. These findings suggest that the Wolbachia infection behaves like a neutral variant in populations. The infection may represent an evolutionary outcome of interactions between Wolbachia infections and their hosts.
220 citations
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04 Apr 2007219 citations
Authors
Showing all 13601 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rasmus Nielsen | 135 | 556 | 84898 |
C. N. R. Rao | 133 | 1646 | 86718 |
James Whelan | 128 | 786 | 89180 |
Jacqueline Batley | 119 | 1212 | 68752 |
Eske Willerslev | 115 | 367 | 43039 |
Jonathan E. Shaw | 114 | 629 | 108114 |
Ary A. Hoffmann | 113 | 907 | 55354 |
Mike Clarke | 113 | 1037 | 164328 |
Richard J. Simpson | 113 | 850 | 59378 |
Alan F. Cowman | 111 | 379 | 38240 |
David C. Page | 110 | 509 | 44119 |
Richard Gray | 109 | 808 | 78580 |
David S. Wishart | 108 | 523 | 76652 |
Alan G. Marshall | 107 | 1060 | 46904 |
David A. Williams | 106 | 633 | 42058 |