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Institution

La Trobe University

EducationMelbourne, Victoria, Australia
About: La Trobe University is a education organization based out in Melbourne, Victoria, Australia. It is known for research contribution in the topics: Population & Health care. The organization has 13370 authors who have published 41291 publications receiving 1138269 citations. The organization is also known as: LaTrobe University & LTU.


Papers
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Journal ArticleDOI
TL;DR: A novel model, stacked autoencoder Levenberg-Marquardt model, which is a type of deep architecture of neural network approach aiming to improve forecasting accuracy, and an optimized structure of the traffic flow forecasting model with a deep learning approach is presented.
Abstract: Forecasting accuracy is an important issue for successful intelligent traffic management, especially in the domain of traffic efficiency and congestion reduction. The dawning of the big data era brings opportunities to greatly improve prediction accuracy. In this paper, we propose a novel model, stacked autoencoder Levenberg-Marquardt model, which is a type of deep architecture of neural network approach aiming to improve forecasting accuracy. The proposed model is designed using the Taguchi method to develop an optimized structure and to learn traffic flow features through layer-by-layer feature granulation with a greedy layerwise unsupervised learning algorithm. It is applied to real-world data collected from the M6 freeway in the U.K. and is compared with three existing traffic predictors. To the best of our knowledge, this is the first time that an optimized structure of the traffic flow forecasting model with a deep learning approach is presented. The evaluation results demonstrate that the proposed model with an optimized structure has superior performance in traffic flow forecasting.

216 citations

Journal ArticleDOI
TL;DR: Wang et al. as mentioned in this paper examined the relationships among HPWS, employee resilience and engagement, using a sample of 2040 employees in the Chinese banking industry, and developed three hypotheses to test the relationship between HPWS and employee resilience, resilience and employee engagement.
Abstract: There is now growing interest in employee resilience in the organizational context and its contribution to organizational performance. However, little is known the extent to which high-performance work system (HPWS) contributes towards enhancing employee’s resilience as well as their levels of engagement. This study examines the relationships among HPWS, employee resilience and engagement, using a sample of 2040 employees in the Chinese banking industry. Drawing on the job demands-resources model and strategic/high-performance human resource management theory, we develop three hypotheses to test the relationship between HPWS and employee resilience, resilience and employee engagement, and the mediating effect of resilience on the relationship between HPWS and engagement. All hypotheses are supported and suggest that HPWS can be used as a job resource to positively affect resilience and subsequently employee engagement. The key message of the paper is that employee resilience can be viewed as a set...

215 citations

Journal ArticleDOI
TL;DR: In surviving animals, PUFA supplementation did not influence infarct size as determined 6 weeks after surgery, but did decrease omega-6-fatty-acid levels, moderate sickness behaviors, acute motor impairment, and longer-term locomotor hyperactivity and depression/anxiety-like behavior.
Abstract: Ischemic stroke is associated with motor impairment and increased incidence of affective disorders such as anxiety/clinical depression. In non-stroke populations, successful management of such disorders and symptoms has been reported following diet supplementation with long chain omega-3-polyunsaturated-fatty-acids (PUFAs). However, the potential protective effects of PUFA supplementation on affective behaviors after experimentally induced stroke and sham surgery have not been examined previously. This study investigated the behavioral effects of PUFA supplementation over a 6-week period following either middle cerebral artery occlusion or sham surgery in the hooded-Wistar rat. The PUFA diet supplied during the acclimation period prior to surgery was found to be associated with an increased risk of acute hemorrhage following the reperfusion component of the surgery. In surviving animals, PUFA supplementation did not influence infarct size as determined 6 weeks after surgery, but did decrease omega-6-fatty-acid levels, moderate sickness behaviors, acute motor impairment, and longer-term locomotor hyperactivity and depression/anxiety-like behavior.

215 citations

Journal ArticleDOI
TL;DR: The involvement of EVs as mediators of signal transduction in neurodegenerative diseases and cancer is discussed and the role of EVs in mediating Wnt and PI3K signaling pathways is also discussed.
Abstract: Extracellular vesicles (EVs) are signaling organelles that are released by many cell types and is highly conserved in both prokaryotes and eukaryotes. Based on the mechanism of biogenesis, these membranous vesicles can be classified as exosomes, shedding microvesicles, and apoptotic blebs. It is becoming clearer that these EVs mediate signal transduction in both autocrine and paracrine fashion by the transfer of proteins and RNA. While the role of EVs including exosomes in pathogenesis is well established, very little is known about their function in normal physiological conditions. Recent evidences allude that EVs can mediate both protective and pathogenic effects depending on the precise state. In this review, we discuss the involvement of EVs as mediators of signal transduction in neurodegenerative diseases and cancer. In addition, the role of EVs in mediating Wnt and PI3K signaling pathways is also discussed. Additional findings on the involvement of EVs in homeostasis and disease progression will promote a better biological understanding, advance future therapeutic, and diagnostic applications.

215 citations

Book
Li Liu1
01 Jan 2004
TL;DR: Li et al. as mentioned in this paper studied the formation of complex societies in prehistoric China during the Neolithic and early state periods, c. 7000-1500 BC, through anthropological perspectives, using systematic analytic methods in settlement and burial patterns.
Abstract: This book studies the formation of complex societies in prehistoric China during the Neolithic and early state periods, c. 7000–1500 BC. Archaeological materials are interpreted through anthropological perspectives, using systematic analytic methods in settlement and burial patterns. Both agency and process are considered in the development of chiefdoms and in the emergence of early states in the Yellow River region. Interrelationships between factors such as mortuary practice, craft specialization, ritual activities, warfare, exchange of elite goods, climatic fluctuations, and environmental changes are emphasized. This study offers a critical evaluation of current archaeological data from Chinese sources, and argues that, although some general tendencies are noted, social changes were affected by multiple factors in no pre-determined sequence. In this most comprehensive study to date, Li Liu attempts to reconstruct developmental trajectories toward early states in Chinese civilization and discusses theoretical implications of Chinese archaeology for the understanding of social evolution.

215 citations


Authors

Showing all 13601 results

NameH-indexPapersCitations
Rasmus Nielsen13555684898
C. N. R. Rao133164686718
James Whelan12878689180
Jacqueline Batley119121268752
Eske Willerslev11536743039
Jonathan E. Shaw114629108114
Ary A. Hoffmann11390755354
Mike Clarke1131037164328
Richard J. Simpson11385059378
Alan F. Cowman11137938240
David C. Page11050944119
Richard Gray10980878580
David S. Wishart10852376652
Alan G. Marshall107106046904
David A. Williams10663342058
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023102
2022398
20213,407
20202,992
20192,661
20182,394