Institution
Laboratory of Molecular Biology
Facility•Cambridge, Cambridgeshire, United Kingdom•
About: Laboratory of Molecular Biology is a facility organization based out in Cambridge, Cambridgeshire, United Kingdom. It is known for research contribution in the topics: Gene & RNA. The organization has 19395 authors who have published 24236 publications receiving 2101480 citations.
Topics: Gene, RNA, DNA, Population, Transcription (biology)
Papers published on a yearly basis
Papers
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TL;DR: It is reported that hepatic expression of interleukin-33 was both required and sufficient for severe hepatic fibrosis in vivo and support the concept of modulation of IL-33 bioactivity for therapeutic purposes.
412 citations
TL;DR: This is the first crystal structure of a member of the serpin family in an uncleaved form and the peptide that is homologous to the reactive centre of inhibitory serpins adopts an alpha-helical conformation.
411 citations
TL;DR: Labile tumour-necrosis-factor-like (TNF) activity was detected by means of an enzyme-linked immunosorbent assay in 50% of 226 freshly obtained serum samples from cancer patients with active disease, but the inducing stimulus and the clinical significance of TNF production in cancer are not understood.
411 citations
TL;DR: The recombinational behavior of int mutants in wild-type and recombination-deficient bacteria suggests that the int + gene determines a site-specific function involved in normal prophage integration and detachment.
410 citations
TL;DR: Physico-chemical experiments show that histones are not evenly distributed in chromatin, and about half of the DNA is “open” and not covered with proteins.
Abstract: Physico-chemical experiments show that histones are not evenly distributed in chromatin. About half of the DNA is “open” and not covered with proteins.
410 citations
Authors
Showing all 19431 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Robert J. Lefkowitz | 214 | 860 | 147995 |
| Ronald M. Evans | 199 | 708 | 166722 |
| Tony Hunter | 175 | 593 | 124726 |
| Marc G. Caron | 173 | 674 | 99802 |
| Mark Gerstein | 168 | 751 | 149578 |
| Timothy A. Springer | 167 | 669 | 122421 |
| Harvey F. Lodish | 165 | 782 | 101124 |
| Ira Pastan | 160 | 1286 | 110069 |
| Bruce N. Ames | 158 | 506 | 129010 |
| Philip Cohen | 154 | 555 | 110856 |
| Gerald M. Rubin | 152 | 382 | 115248 |
| Ashok Kumar | 151 | 5654 | 164086 |
| Kim Nasmyth | 142 | 294 | 59231 |
| Kenneth M. Yamada | 139 | 446 | 72136 |
| Harold E. Varmus | 137 | 496 | 76320 |