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Institution

Ladoke Akintola University of Technology

EducationOgbomoso, Nigeria
About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.


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Journal ArticleDOI
TL;DR: It is suggested that NG/17–0500 belongs to HEV subtype 2b (HEV-2b) from Sub-Saharan Africa, which is the second complete HEV- 2 sequence to date, whose natural history and epidemiology merit further investigation.
Abstract: In 2017 the Nigerian Ministry of Health notified the World Health Organization (WHO) of an outbreak of hepatitis E located in the north-east region of the country with 146 cases with 2 deaths. The analysis of the hepatitis E virus (HEV) genotypes responsible for the outbreak revealed the predominance of HEV genotypes 1 (HEV-1) and 2 (HEV-2). Molecular data of HEV-2 genomes are limited; therefore we characterized a HEV-2 strain of the outbreak in more detail. The full-length genome sequence of an HEV-2 strain (NG/17–0500) from the outbreak was amplified using newly designed consensus primers. Comparison with other HEV complete genome sequences, including the only HEV-2 strain (Mex-14) with available complete genome sequences and the availability of data of partial HEV-2 sequences from Sub-Saharan Africa, suggests that NG/17–0500 belongs to HEV subtype 2b (HEV-2b). We identified a novel HEV-2b strain from Sub-Saharan Africa, which is the second complete HEV-2 sequence to date, whose natural history and epidemiology merit further investigation.

25 citations

Journal ArticleDOI
TL;DR: The elevated liver enzymes seen in women with pre-eclampsia may be due to free radical injury to the liver.
Abstract: Background: One of the features associated with pre-eclampsia is elevated liver transaminases. The reason this happens has not been fully described. However, the hepatocytes are not known to be spared by free radical injury. This study was conducted to examine the relationship between product of free radical injury (malondialdehyde) and transaminases in pre-eclamptic women. Patients and methods: A total of 98 and 115 pre-eclamptic and apparently normal pregnant women were selected from the booking clinic of Ladoke Akintola University of Technology Teaching Hospital, Osogbo. Non-pregnant women were selected from volunteered members of staff. Malondialdehyde (MDA), aspartate transaminase (AST) and alanine transaminase (ALT) analyses were determined on collected venous blood sample. Statistical analyses of variables were done using SPSS 17 taking level of significance to be p<0.05. Results: Subjects with plasma AST between 10 and 20U/L had mean plasma MDA of 0.92μmol/l whereas those with plasma levels greater than 41U/L had mean plasma MDA of 4.72μmol/l. Similarly, Subjects with plasma ALT between 10 and 20U/L had mean plasma MDA of 0.86μmol/l, and subjects with plasma ALT greater than 51 U/L had mean plasma MDA of 4.71μmol/l. Positive correlation was observed between AST and ALT(r=0.79;p=0.047), between AST and MDA(r=0.690; p=0.061) as well as between ALT and MDA(r=0.571;p=0.049). Conclusion: The elevated liver enzymes seen in women with pre-eclampsia may be due to free radical injury to the liver. Pre-eclamptic women without free radical injury did not have elevated transaminases Keywords: Pre-eclempsia, free radical, malondialdehyde, alanine and aspartate aminotransaminases

25 citations

11 Feb 2014
TL;DR: The wide spread infection among the pupils is attributed to poor hygienic condition and the low socioeconomic status of these communities and with more coordinated control efforts the parasites can be eradicated.
Abstract: had double infection. Six STH were recorded in this study namely: Ascaris lumbricoides 59 (36.4%), hookworm 9 (5.6%), Strongyloides stercoralis 6 (3.7%), Teania spp. 2 (1.2%), Schistosoma mansoni and Hymenolepis nana 1 (0.6%) each. The intensity of infection based on the number of egg in 1 g of stool was categorized into severe, moderate and heavy infection. None of the children had heavy infection while 44 (27.0%) of those infected with A. lumbricodes had light infection and 7 (4.3%) had moderate infection. No significant difference was observed when the mean weight and height of infected and non-infected pupils were compared. The wide spread infection among the pupils is attributed to poor hygienic condition and the low socioeconomic status of these communities. The low intensity recorded is an indication that with more coordinated control efforts the parasites can be eradicated. Education on proper hygiene habits and regular de-worming exercise especially at the primary school level is recommended.

25 citations

Journal ArticleDOI
TL;DR: It is suggested that multiple parasitic infections are common in school age children in rural communities of Kwara State Nigeria and the Hymenolepis spp.
Abstract: Background Malaria and intestinal helminths co-infection are major public health problems particularly among school age children in Nigeria. However the magnitude and possible interactions of these infections remain poorly understood. This study determined the prevalence, impact and possible interaction of Plasmodium falciparum and intestinal helminths co-infection among school children in rural communities of Kwara State, Nigeria.

25 citations

Journal ArticleDOI
TL;DR: In this article, the effects of drying air temperature and slice thickness on the drying characteristics, drying time and energy requirement of drying process was determined, and the results have shown that an increase in the driening air temperature causes shorter drying times.
Abstract: The thin layer drying behaviour of ginger slices in a laboratory dryer was examined. The slices of 5 mm, 10 mm and 15 mm thicknesses were dried using heated ambient air at temperatures from 40 to 70 oC and air velocity of 1.5 m/s. The effects of drying air temperature and slice thickness on the drying characteristics, drying time and energy requirement of drying process was determined. The results have shown that an increase in the drying air temperature causes shorter drying times. Thinner slices also causes a shorter drying time. The effective moisture diffusivity values increased from 3.36814 × 10-10 m2/s to 5.82524 × 10-9 m2/s while the activation energy values for different slice thickness of ginger varied from 196.15 to 198.79 kJ/mol. The total needed energy varied from 735.3 to 868.5 kWh while the value of specific energy requirement varied from 3676.6 to 4342.4 kWh/kg respectively.

25 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202310
202221
2021365
2020366
2019256
2018227