Ladoke Akintola University of Technology

About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.

Onion (Allium cepa) extract prevents cadmium induced renal dysfunction

Abstract: Cadmium (Cd), a heavy metal, is known for its adverse effects on the body. In this study, the lowering effect of Cd on renal clearance (RC) was investigated, and Allium cepa extract (AcE) (an antioxidant) was pre-administered orally to prevent Cd's adverse effects. Seventy-two Wistar rats, grouped into three (n = 24), were used for this study. While Group C was given 1.0 ml of AcE daily (orally), Group A and Group B were given distilled water. AcE administration was done for eight weeks. Afterwards B and C were then given 1.5 ml/kg BW of 0.3 mg/L 3CdSO4.8H2O intraperitoneally for three consecutive days. The results obtained showed that Cd causes significant reduction in the 24 hour urine volume (from 3.017 ± 0.125 to 2.433 ± 0.118 ml), RC (from 3.258 ± 0.114 to 1.357 ± 0.104 ml/h for creatinine; and from 0.350 ± 0.057 to 0.185 ± 0.055 ml/h for urea), plasma and tissue SOD and CAT activity (form 1.644 ± 0.036 to 1.307 ± 0.056 u/g protein for plasma SOD; 0.391 ± 0.029 to 0.2692 ± 0.031 u/protein for plasma CAT; 1.695 ± 0.034 to 1.327 ± 0.049 u/g protein for tissues SOD; and from 0.350 ± 0.027 to 0.273 ± 0.043 u for tissue CAT), and significant MDA increased in plasma (from 1496.79 ± 1.321 to 1679.48 ± 143.29 μg/g protein) and tissue (from 1265.22 ± 2.285 to 1669.87 ± 14.61 μg/dL). AcE, however, prevents these Cd's adverse effects. This findings lead to the conclusion Cd exposure causes renal dysfunction, but oral administration of onion could prevent it.

Patterns and Correlates of Intimate Partner Violence to Women Living With HIV/AIDS in Osogbo, Southwest Nigeria

Abstract: We assessed the prevalence and correlates of intimate partner violence (IPV) to women living with HIV/AIDS in an antiretroviral clinic in Nigeria. Three hundred sixty respondents were interviewed using a structured questionnaire. Sixty percent were married, of which 24% had disclosed HIV status to their partner. About a quarter (23.6%) had experienced IPV since HIV diagnosis. Types of violence experienced were physical violence (17%), emotional violence (21%), and sexual violence (2%). Predictors of IPV included having a younger aged partner, disclosing status, and partner's alcohol use (p = .001). Suggestions to prevent IPV include increasing public awareness and family counseling.

The Essential Oil from the Leaves and Flowers of “African Marigold,” Tagetes erecta L.

Abstract: The essential oils from the leaves and flowers of Tagetes erecta L. cultivated in Nigeria were examined by GC and GC/MS. Piperitone (50.7%), piperitenone (13.2%) and (E)-β-ocimene (6.7%) were the predominant components in the leaf oil. The flower oil was characterized by the presence of 1, 8-cineole (23.1%), α-pinene (11.8%), α-terpineol (10.7%), piperitone (8.0%) and sabinene (5.6%) as the major compounds.

Sequestering a non-steroidal anti-inflammatory drug using modified orange peels

Abstract: This study investigates the sorption of a non-steroidal anti-inflammatory drug, ibuprofen, (IBP) using acid activated carbon prepared from orange peel (OPA) OPA was characterized via the use of Fourier transform infrared and scanning electron microscopy techniques Four isotherm models were utilized to assess the adsorption data: Langmuir, Freundlich, Temkin, and Dubinin–Raduskevich, respectively It was established that the IBP adsorption onto OPA fitted Langmuir isotherm model most The optimum monolayer adsorption capacity of OPA was 4930 mg/g at 50 °C The adsorption data was subjected to kinetic test using pseudo-first-order and pseudo-second-order, Elovich, and intraparticle diffusion models The sorption process was best described by pseudo-second-order kinetic model The mean heat of adsorption, Ea at all temperatures studied was < 800 kJmol−1, signifying that the sorption mechanism is physisorption Thermodynamic study reveals that the adsorption is spontaneous and exothermic OPA was established to be a viable and effective adsorbent for the sorption of IBP from aqueous medium