Ladoke Akintola University of Technology

About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.

Comparison between CANSCORE and other anthropometric indicators in fetal malnutrition.

Abstract: Objective Early detection of malnutrition in newborn babies is of major importance in order to prevent associated serious sequelae. Main objective of the study was to compare various anthropometric methods with Clinical assessment of nutritional status score (CANSCORE) in assessing fetal malnutrition.

Toxicity of cassava wastewater effluents to african catfish: clarias gariepinus (burchell, 1822)

Abstract: The relative lethal and sublethal toxicity of cassava wastewater effluents from a local food factory were investigated on Clarias gariepinus fingerlings using a renewable static bioassay. The physico-chemical characteristics of the cassava wastewater effluents showed a number of deviations from the standards of the Federal Environmental Protection Agency (FEPA) on the guidelines for effluent discharges. Considering the pollutants of the effluent, cyanide (CN) is suspected to be primarily responsible for the toxicity, although synergistic effect of other pollutants cannot be ruled out. At each exposure, in the two tests, the test-organisms showed signs of serious stress, swimming pattern changed and mortality increased over relatively small increase in concentration. The LC 50 for lethal and sublethal tests were 0.024 mg1 -1 and 0.0064 mg1 -1 , respectively. The differences observed in the mortalities and bioconcentration of metals in fish muscles of varying concentrations were significant (p Keywords : bioconcentration, Clarias gariepinus , effluent, toxicity, wastewater SINET: Ethiopian Journal of Science Vol. 28(2) 2005: 189-194

Changes in serum leptin during phases of menstrual cycle of fertile women: relationship to age groups and fertility

Abstract: Background: It is established that serum level of leptin is affected by transitional phases of reproduction. It is also reported that the puberty is triggered when body fat and circulating levels of leptin exceed the critical thresholds, butthere is less focus on the serum level of leptin and its relationship with different phases of menstrual cycle and the fertility. Objectives: The present study try to determines the serum concentration of leptin and fertility hormonesin the various phases of normal menstrual cycle of fertile women and compare any difference in serum concentration between age groups of 18-30 years and 31-41 years It is a well known fact that fertility start to decrease from age 31 years. Patients and Methods: A total of 118 healthy fertile women with normal menstrual cycle aged between 18-40, were divided into two age groups (n = 65) 18-30 years and (n = 53) 31-40 years. Serum concentrations of leptin, estradiol, progesterone, luteinising hormone (LH) and follicle-stimulating hormone (FSH) were measured on day1 (menstrual phase), day7 (proliferative/follicular phase), day14 (ovulatory phase), day21 (luteal phase) and day 28(secretory phase) of the menstrual cycle. Results: There was a significant increase (P < 0.05) in leptin levels on day 14 (12.75 + 5.8 ng/mL) and day 21 (12.91 + 3.2 ng/mL) for age group 18-30 years compared to day 14 (11.60 + 3.2 ng/mL) and day 21 (11.60 + 3.2 ng/mL) for age group 31-40 years. Leptin was positively correlated with FSH on day 14, with LH on day 7 and day 21; likewise, with progesterone on day 21 and day 28 and with estradiol on day 7 and day 14 for both age groups. Conclusions: The serum leptin level was at the lowest level during the menstrual and secretory phase and the highest level was around the luteal phase. The significant increase ofleptin in the younger age group raise this question whether circulating leptin has any role to play in the age of pregnancy and fertility. Data in this study shows that leptin level was affected with increase in age; therefore changes in leptin level will affect fertility in this study suggest that there may be a relation between leptin levels and fertility.

Investigation of the influence of lineaments, lineament intersections and geology on groundwater yield in the basement complex terrain of Ondo State, Southwestern Nigeria

Abstract: The influence of lineaments, lineament intersections and geology on the groundwater yield of the basement terrain of Ondo State was investigated using optical remote sensing data, Aster DEM, geology, and borehole yield data. Landsat-7 ETM+ and Aster DEM were processed to generate composite lineament map. The study area was traversed by five (5) main lineament populations trending N–S, NE–SW, E–W, ENE–WSW, NNW–SSE. Boreholes sited on lineament exhibited a yield range of between 0.8 and 1.28 l/s with an average yield of 1.04 l/s. Boreholes sited close to lineament gave groundwater yield values of between 0.5 and 1.28 l/s and an average yield of 1 l/s, while boreholes located outside lineament gave groundwater yield range of between 0.2 and 1.26 l/s with an average yield of 0.98 l/s. The investigation of the hydrogeological characteristics of the lithologies by superimposing the yield data showed average yield of 0.98 l/s for migmatite gneiss biotite granite undifferentiated (M), 1.01 l/s for porphyritic granite (OGp), 1.03 l/s for medium- to coarse-grained (OGe), 1.17 l/s for pelitic schist undifferentiated (Su), 1.24 l/s for quartz schist and quartzite (Eq), 1.12 l/s for older granite undifferentiated (OGu), 0.5 l/s for slightly migmatised medium-grained granite-gneiss (gg) and 1.23 l/s for fine-grained flaggy quartzite and schists (Sf). The study concluded that borehole data located on or near lineaments or at intersection of lineaments gave higher yields more than those located before lineaments or outside lineaments, while quartz schist and quartzite exhibited the highest average groundwater yield of all the lithological units.

Efficacy of praziquantel in the treatment of Schistosoma haematobium infection among school-age children in rural communities of Abeokuta, Nigeria.

Abstract: Background: Chemotherapy with praziquantel (PZQ) has been the cornerstone of schistosomiasis control over the last two decades. Being the only available drug for the treatment of over 200 million people worldwide, continuous monitoring of PZQ efficacy under the pressure of widespread use is therefore advocated. Methods: The efficacy of taking two doses of oral PZQ for the treatment of Schistosoma haematobium was examined among school children in Nigeria. Urine specimens were collected from 350 school children and examined using the filtration technique. Blood was collected for packed cell volume (PCV) estimation, and the weight and height of each child were estimated. S. haematobium egg positive pupils were treated with two oral doses of PZQ at 40 mg/kg with a four-week interval in between. Drug efficacy was determined based on the egg reduction rate (ERR). Results: Among 350 school children, 245 (70.0%) – of which 132 were males and 113 were females, with an age range of 4 to 15 years – were diagnosed with S. haematobium. All the 245 infected children received a single oral dose of 40 mg/kg PZQ twice with a four-week interval in between and were followed up for 12 weeks. At four, eight and twelve weeks post treatment, the ERR was 57.1%, 77.6% and 100%, respectively. The ERR was significantly higher among the children with a light infection compared to those with a heavy infection. One hundred and twenty-one children were egg negative at four weeks post treatment, among which 1 (6.3) and 120 (52.4%) had heavy and light infections, respectively. Following the second round of treatment, the cure rate at eight weeks and twelve weeks was 85.3% and 100%, respectively. Conclusion: This study demonstrated the efficacy of taking two doses of oral PZQ for the treatment of urinary schistosomiasis among school children in Nigeria.