Ladoke Akintola University of Technology

About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.

Pathogenic intestinal parasites and bacterial agents in solid wastes.

Abstract: Objective: To determine the profile of potentially pathogenic enteric parasites and bacterial agents in municipal refuse dumps in Ibadan Nigeria. Design: A cross-sectional survey. Setting: Five major market places refuse dumps in Ibadan municipality Nigeria. Methods: The major market places in Ibadan city were randomly selected by lottery method. The refuse sludge were sampled and examined parusitologically and bacteriologically using the methods as described. Data analysis was done by using chi square test where applicable. Results: Cases of multiple intestinal parasites and bacterial agents were commonly encountered in the sludge refuse samples. The commonly found parasitic agents were of both human and veterinary importance. These include Ascaris Lumbricoides (9.3 egp) Entamoeba histolytica (8.07 cyst per gram) Hookworndstrongyle (6.27 egp) and Ascaris suum (1.07 egp). Others were Ascaris vitolorum (1.09epg) Strongyloides papillosu (0.52 larvae per gram.) Schistosoma suis (0.31 epg) Dicrocoelium dendriticum(O.9egp). The most commonly found bacterial agents were Klebsiella species Escherichia Coli Proteus species streptococci and other gram-positive organisms. Climatic conditions affected the distribution of both parasites and bacterial agents in the sludge (P<0.001). More intestinal parasites 2423 (53.4%) and bacterial agents 2150 (27.2%) were encountered at mean air temperature 26.1 ± 0.6 mean relative humidity of 72 ± 3.5%. The degree of contamination by market locations varies significantly (P<0.001). Conclusion: A high degree of contamination of solid waste dumpsites with bacterial and parasitic agents was observed in the present study. As a result of the public health importance of the organisms isolated it is opined that well planned waste management and health education programs will go a long way to reduce the potential epidemic risks posed by such sites in Ibadan Nigeria. (authors)

Curcuma longa extract as a histological dye for collagen fibres and red blood cells.

Abstract: Crude ethanolic extract and column chromatographic fractions of the Allepey cultivar of Curcuma longa Roxb, commonly called turmeric (tumeric) in commerce, were used as a stain for tissue sections. Staining was carried out under basic, acidic and neutral media conditions. Inorganic and organic dissolution solvents were used. The stain was used as a counterstain after alum and iron haematoxylins. C. longa stained collagen fibres, cytoplasm, red blood cells and muscle cells yellow. It also stained in a fashion similar to eosin, except for its intense yellow colour. Preliminary phytochemical evaluation of the active column fraction revealed that it contained flavonoids, free anthraquinone and deoxy sugar. A cheap, natural dye can thus be obtained from C. longa.

Prevalence of Tinea Capitis among Children in Osogbo, Nigeria, and the Associated Risk Factors.

Abstract: Tinea capitis is a fungi infection of the scalp that disproportionately affects children in rural and underserved communities in Nigeria. A case-control study was conducted to identify the causative agents and factors that predispose school pupils to tinea capitis in two selected government-owned public primary schools in Osogbo, Southwestern Nigeria. A total of 230 participants were included in the study: 115 cases and 115 controls. Head scrapings were collected from pupils with suspected T. capitis lesions, viewed under Potassium Hydroxide smear microscopy and cultured in Sabouraud’s Dextrose Agar (SDA) for characteristic fungal elements. A total of 105 (91%) samples were successfully cultured, of which 56% (59/105) were from male pupils. Tricophyton rubrum (34%), Tricophyton mentagrophyte (31%) and Microsporum canis (18%) were the most prevalent organisms. Other dermatophytes obtained include Microsporum nanuum (3%), Epidermophyton floccusum (6%), Tricophyton verucosum (1%), and Microsporum gypseum (8%). Pupils between the ages of 4 and 7 years had the highest distribution (67%) followed by those between the ages of 8 and 11 years (39%). Playing with animals, the sharing of combs and not bathing with soap were significantly associated with tinea capitis infection (P < 0.05) in each case. This study showed a high prevalence of tinea capitis caused by the identified dermatophytes in the area.

Target organ damage and associated clinical conditions among Nigerians with treated hypertension.

Abstract: AIM Systemic hypertension is the commonest noncommunicable disease in Nigeria. Hypertension is linked with certain target organ damage (TOD) and associated clinical conditions (ACC). This study assessed the extent, pattern and predictors of TOD/ACC in patients with hypertension in Nigeria. METHODS The study was carried out at the medical outpatient department of a state hospital in Nigeria. Target organ damage was assessed in these patients. Predictors of TOD/ACC were also sought. RESULTS A total of 203 patients [73 men (36.0%) and 130 women (64.0%)] constituted the study population. One hundred and twenty-two patients (60.1%) had TOD/ACC. The prevalent TOD/ACC were left ventricular hypertrophy (LVH) (31.0%), chronic kidney disease (18.2%), diabetic nephropathy (18.2%), heart failure (10.8%) and cerebrovascular disease (CVD) (8.9%). There was a statistically significant association between systolic blood pressure and TOD/ACC. Patients with over all blood pressure (BP) control (i.e. BP or = 140/90 mmHg) although the difference was not statistically significant (Chi2= 1.5, p > 0.05). The association between length of treatment and TOD/ACC approached significance ( Chi2= 9.35, p = 0.053). CONCLUSION The study showed a high prevalence of TOD/ACC in treated hypertensives. A positive association was shown between systolic BP and TOD/ACC. Early detection of hypertension and strict blood pressure control should help in reducing TOD/ACC in the hypertensive population.