Institution
Leibniz University of Hanover
Education•Hanover, Niedersachsen, Germany•
About: Leibniz University of Hanover is a education organization based out in Hanover, Niedersachsen, Germany. It is known for research contribution in the topics: Finite element method & Population. The organization has 14283 authors who have published 29845 publications receiving 682152 citations.
Topics: Finite element method, Population, Laser, Gravitational wave, Membrane
Papers published on a yearly basis
Papers
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TL;DR: The present paper summarises experimental evidence which offers new avenues in the understanding of Al toxicity and resistance in maize and suggests that the rapid disorganisation of the cytoskeleton leading to root growth inhibition may be mediated by interaction of Al with the apoplastic side of the cell wall – plasma membrane – cytos skeleton continuum.
Abstract: The mechanism of aluminium-induced inhibition of root elongation is still not well understood It is a matter of debate whether the primary lesions of Al toxicity are apoplastic or symplastic The present paper summarises experimental evidence which offers new avenues in the understanding of Al toxicity and resistance in maize Application of Al for 1 h to individual 1 mm sections of the root apex only inhibited root elongation if applied to the first 3 apical mm The most Al-sensitive apical root zone appeared to be the 1–2 mm segment Aluminium-induced prominent alterations in both the microtubular (disintegration) and the actin cytoskeleton (altered polymerisation patterns) were found especially in the apical 1–2 mm zone using monoclonal antibodies Since accumulation of Al in the root apoplast is dependent on the properties of the pectic matrix, we investigated whether Al uptake and toxicity could be modulated by changing the pectin content of the cell walls through pre-treatment of intact maize plants with 150 mM NaCl for 5 days NaCl-adapted plants with higher pectin content accumulated more Al in their root apices and they were more Al-sensitive as indicated by more severe inhibition of root elongation and enhanced callose induction by Al This special role of the pectic matrix of the cell walls in the modulation of Al toxicity is also indicated by a close positive correlation between pectin, Al, and Al-induced callose contents of 1 mm root segments along the 5 mm root apex On the basis of the presented data we suggest that the rapid disorganisation of the cytoskeleton leading to root growth inhibition may be mediated by interaction of Al with the apoplastic side of the cell wall – plasma membrane – cytoskeleton continuum
156 citations
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TL;DR: The most recent efforts undertaken in order to combine at least two of these properties in a hybrid system are summarized.
156 citations
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TL;DR: Advanced root phenotyping tools will allow dissection of root responses into specific root phenes that will aid both conventional and molecular breeders to develop superior cultivars that will play a key role in sustainable intensification of crop–livestock systems.
156 citations
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TL;DR: In this paper, the authors present Flow Boiling and Heat Transfer Model (FTM) with Flow Map, Flow Patterns and Co2 Reference LTCM-ARTICLE-2006-014.
156 citations
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Katholieke Universiteit Leuven1, Emory University2, UCL Institute of Neurology3, Cleveland Clinic4, Pontifícia Universidade Católica de Goiás5, University of Dundee6, Toronto Western Hospital7, Karolinska Institutet8, Jaslok Hospital9, Aix-Marseille University10, Alfaisal University11, Shanghai Jiao Tong University12, Ninewells Hospital13, North Shore University Hospital14, Cornell University15, Harvard University16, Ohio State University17, Leibniz University of Hanover18, University of Miami19, Yonsei University20, Otto-von-Guericke University Magdeburg21, Brown University22, Capital Medical University23
TL;DR: This consensus document on ethical and scientific conduct of psychiatric surgery worldwide is designed to enhance patient safety and address a broad range of neuropsychiatric disorders, brain targets and neurosurgical techniques.
Abstract: Background For patients with psychiatric illnesses remaining refractory to ‘standard’ therapies, neurosurgical procedures may be considered. Guidelines for safe and ethical conduct of such procedures have previously and independently been proposed by various local and regional expert groups. Methods To expand on these earlier documents, representative members of continental and international psychiatric and neurosurgical societies, joined efforts to further elaborate and adopt a pragmatic worldwide set of guidelines. These are intended to address a broad range of neuropsychiatric disorders, brain targets and neurosurgical techniques, taking into account cultural and social heterogeneities of healthcare environments. Findings The proposed consensus document highlights that, while stereotactic ablative procedures such as cingulotomy and capsulotomy for depression and obsessive-compulsive disorder are considered ‘established’ in some countries, they still lack level I evidence. Further, it is noted that deep brain stimulation in any brain target hitherto tried, and for any psychiatric or behavioural disorder, still remains at an investigational stage. Researchers are encouraged to design randomised controlled trials, based on scientific and data-driven rationales for disease and brain target selection. Experienced multidisciplinary teams are a mandatory requirement for the safe and ethical conduct of any psychiatric neurosurgery, ensuring documented refractoriness of patients, proper consent procedures that respect patient’s capacity and autonomy, multifaceted preoperative as well as postoperative long-term followup evaluation, and reporting of effects and side effects for all patients. Interpretation This consensus document on ethical and scientific conduct of psychiatric surgery worldwide is designed to enhance patient safety.
156 citations
Authors
Showing all 14621 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hyun-Chul Kim | 176 | 4076 | 183227 |
Peter Zoller | 134 | 734 | 76093 |
J. R. Smith | 134 | 1335 | 107641 |
Chao Zhang | 127 | 3119 | 84711 |
Benjamin William Allen | 124 | 807 | 87750 |
J. F. J. van den Brand | 123 | 777 | 93070 |
J. H. Hough | 117 | 904 | 89697 |
Hans-Peter Seidel | 112 | 1213 | 51080 |
Karsten Danzmann | 112 | 754 | 80032 |
Bruce D. Hammock | 111 | 1409 | 57401 |
Benno Willke | 109 | 508 | 74673 |
Roman Schnabel | 108 | 589 | 71938 |
Jan Harms | 108 | 447 | 76132 |
Hartmut Grote | 108 | 434 | 72781 |
Ik Siong Heng | 107 | 423 | 71830 |