Institution
Leibniz University of Hanover
Education•Hanover, Niedersachsen, Germany•
About: Leibniz University of Hanover is a education organization based out in Hanover, Niedersachsen, Germany. It is known for research contribution in the topics: Finite element method & Computer science. The organization has 14283 authors who have published 29845 publications receiving 682152 citations.
Papers published on a yearly basis
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TL;DR: The newly developed MOF membrane ZIF-8 separates an equimolar ethene/ethane mixture at room temperature for 1 and 6 bar feed pressure, respectively, with a selectivity of 2.8 and 2.4 as discussed by the authors.
363 citations
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TL;DR: It is demonstrated that corresponding coronal dentine layers of human deciduous and permanent molars, and of bovine central incisors, are not significantly different in their number of tubules per mm(2) and their tubule diameter, whereas tubule density in bovines root dentine is significantly higher.
362 citations
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TL;DR: Two multiplex RT-PCR assays with specific coamplification of plant mRNA as an internal control from total nucleic acids are described for the parallel detection of Apple chlorotic leaf spot virus,Apple stem pitting virus, Apple mosaic virus and Apple stem grooving virus.
361 citations
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TL;DR: In this paper, a 3D ZnIn2S4/TiO2 Z-scheme photocatalysts were constructed for photochemical reduction of CO2 into renewable hydrocarbon fuels without the use of a solid state electron mediator.
Abstract: A 3-dimensional (3D) ZnIn2S4/TiO2 Z-scheme system has been designed and constructed for photocatalytic reduction of CO2 into renewable hydrocarbon fuels without the use of a solid-state electron mediator. The unique 3D morphology, achieved by assembling 2D ZnIn2S4 nanosheets onto 1D TiO2 nanobelts, not only provides large surface area but also improves the separation and transfer efficiency of photogenerated electrons and holes. The 3D ZnIn2S4/TiO2 Z-scheme photocatalysts show excellent light-harvesting properties demonstrated in photocatalytic reduction of CO2, resulting in generation of desired hydrocarbons. The CH4 production rate of the 3D ZnIn2S4/TiO2 can reach up to 1.135 μmol g−1 h−1, which is about 39-times higher than that of bare ZnIn2S4 (0.029 μmol g−1 h−1). The enhanced photocatalytic activity is attributed to effective separation of the charge carriers between ZnIn2S4 and TiO2 through the direct Z-scheme instead of a type-II heterojunction. The photogenerated electrons in TiO2 nanobelts recombine with the holes in ZnIn2S4 nanosheets, and the unrecombined electrons/holes on different active sites have stronger reduction/oxidation abilities, leading to higher photocatalytic activity for CO2 reduction.
360 citations
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Mayo Clinic1, University of Florence2, University of Insubria3, Cornell University4, Icahn School of Medicine at Mount Sinai5, University of Texas MD Anderson Cancer Center6, University of Texas Health Science Center at San Antonio7, University of Paris8, Heidelberg University9, University of Barcelona10, Guy's and St Thomas' NHS Foundation Trust11, Queen's University Belfast12, RWTH Aachen University13, Catholic University of the Sacred Heart14, University of Hamburg15, Leibniz University of Hanover16, Uppsala University17
TL;DR: This document updates the recommendations on the management of Philadelphia chromosome-negative myeloproliferative neoplasms (Ph-neg MPNs), and both recombinant interferon alpha and the JAK1/JAK2 inhibitor ruxolitinib are recommended as second-line therapies for PV patients who are intolerant or have inadequate response to hydroxyurea.
Abstract: This document updates the recommendations on the management of Philadelphia chromosome-negative myeloproliferative neoplasms (Ph-neg MPNs) published in 2011 by the European LeukemiaNet (ELN) consortium. Recommendations were produced by multiple-step formalized procedures of group discussion. A critical appraisal of evidence by using Grades of Recommendation, Assessment, Development and Evaluation (GRADE) methodology was performed in the areas where at least one randomized clinical trial was published. Seven randomized controlled trials provided the evidence base; earlier phase trials also informed recommendation development. Key differences from the 2011 diagnostic recommendations included: lower threshold values for hemoglobin and hematocrit and bone marrow examination for diagnosis of polycythemia vera (PV), according to the revised WHO criteria; the search for complementary clonal markers, such as ASXL1, EZH2, IDH1/IDH2, and SRSF2 for the diagnosis of myelofibrosis (MF) in patients who test negative for JAK2V617, CALR or MPL driver mutations. Regarding key differences of therapy recommendations, both recombinant interferon alpha and the JAK1/JAK2 inhibitor ruxolitinib are recommended as second-line therapies for PV patients who are intolerant or have inadequate response to hydroxyurea. Ruxolitinib is recommended as first-line approach for MF-associated splenomegaly in patients with intermediate-2 or high-risk disease; in case of intermediate-1 disease, ruxolitinib is recommended in highly symptomatic splenomegaly. Allogeneic stem cell transplantation is recommended for transplant-eligible MF patients with high or intermediate-2 risk score. Allogeneic stem cell transplantation is also recommended for transplant-eligible MF patients with intermediate-1 risk score who present with either refractory, transfusion-dependent anemia, blasts in peripheral blood > 2%, adverse cytogenetics, or high-risk mutations. In these situations, the transplant procedure should be performed in a controlled setting.
360 citations
Authors
Showing all 14621 results
Name | H-index | Papers | Citations |
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Hyun-Chul Kim | 176 | 4076 | 183227 |
Peter Zoller | 134 | 734 | 76093 |
J. R. Smith | 134 | 1335 | 107641 |
Chao Zhang | 127 | 3119 | 84711 |
Benjamin William Allen | 124 | 807 | 87750 |
J. F. J. van den Brand | 123 | 777 | 93070 |
J. H. Hough | 117 | 904 | 89697 |
Hans-Peter Seidel | 112 | 1213 | 51080 |
Karsten Danzmann | 112 | 754 | 80032 |
Bruce D. Hammock | 111 | 1409 | 57401 |
Benno Willke | 109 | 508 | 74673 |
Roman Schnabel | 108 | 589 | 71938 |
Jan Harms | 108 | 447 | 76132 |
Hartmut Grote | 108 | 434 | 72781 |
Ik Siong Heng | 107 | 423 | 71830 |