Institution
Leicester Royal Infirmary
Healthcare•Leicester, United Kingdom•
About: Leicester Royal Infirmary is a healthcare organization based out in Leicester, United Kingdom. It is known for research contribution in the topics: Population & Carotid endarterectomy. The organization has 5300 authors who have published 6204 publications receiving 208464 citations.
Papers published on a yearly basis
Papers
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TL;DR: This questionnaire provides a framework for teaching and auditing the effectiveness of an educational program and knowledge about the assessment and management of undernutrition among doctors, medical students, nurses and pharmacists was poor.
77 citations
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TL;DR: Gastrointestinal tract motility may be reduced markedly after surgery with delay in gastric emptying, induced partly by surgery, partly by the residual effects of anaesthetic agents, and particularly by opioids administered for post-operative pain relief.
Abstract: Gastrointestinal tract motility may be reduced markedly after surgery with delay in gastric emptying. these alterations are induced partly by surgery, partly by the residual effects of anaesthetic agents, and particularly by opioids administered for post-operative pain relief. These changes may be antagonized to a certain extent by administration of prokinetic agents such as cisapride. Post-operative ileus reduces the rate of mobilization and may also reduce or delay absorption of drugs administered by the gastrointestinal tract. Furthermore, post-operative nausea and vomiting, multi-factorial in aetiology, may ensue and also be responsible for delayed mobilization, subjective discomfort and delay in administration of oral agents post-operatively. A serious problem may be leakage from bowel anastomoses. Although the causes are primarily surgical, an increase in bowel contractility may be deleterious and it has been suggested that neostigmine and morphine may be implicated in anastomotic dehiscence.
77 citations
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TL;DR: Although increasing age is associated with lower cardiac baroreceptor sensitivity and cerebral blood flow velocity, dynamic CA during orthostatic stress is unaffected by physiological aging.
Abstract: Background and Purpose— Physiological aging is associated with many changes in the cardiovascular and cerebrovascular systems, but dynamic cerebral autoregulation (CA) during supine rest shows no age-related changes. Because syncopal syndromes usually occur during orthostatic stress and their prevalence increases with age, it is important to define the effect of aging on dynamic CA during orthostatic stress. Methods— Twenty-five younger subjects (≤40 years) and 25 sex-matched older subjects (≥60 years) underwent 70° head-up tilt for 30 minutes. Bilateral middle cerebral artery blood flow velocities were measured with transcranial Doppler ultrasound, along with noninvasive continuous measurements of arterial blood pressure, heart rate, and transcutaneous and end-tidal carbon dioxide concentrations. By comparing actual changes in cerebral blood flow velocity to changes predicted by a model based on arterial blood pressure changes, we derived dynamic autoregulatory indexes for each subject for periods before...
77 citations
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TL;DR: Lung cancer surgery provided by specialists within a multidisciplinary team resulted in increased surgical resection rates without compromising outcome, strengthening the case for disease-specific specialists in the treatment of lung cancer.
77 citations
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TL;DR: Platelet and microvessel counts are both potential prognostic markers for NSCLC and the role of platelets in the angiogenic process needs to be further investigated.
77 citations
Authors
Showing all 5314 results
Name | H-index | Papers | Citations |
---|---|---|---|
George Davey Smith | 224 | 2540 | 248373 |
Nilesh J. Samani | 149 | 779 | 113545 |
Peter M. Rothwell | 134 | 779 | 67382 |
John F. Thompson | 132 | 1420 | 95894 |
James A. Russell | 124 | 1024 | 87929 |
Paul Bebbington | 119 | 583 | 46341 |
John P. Neoptolemos | 112 | 648 | 52928 |
Richard C. Trembath | 107 | 368 | 41128 |
Andrew J. Wardlaw | 92 | 311 | 33721 |
Melanie J. Davies | 89 | 814 | 36939 |
Philip Quirke | 89 | 378 | 34071 |
Kenneth J. O'Byrne | 87 | 629 | 39193 |
David R. Jones | 87 | 707 | 40501 |
Keith R. Abrams | 86 | 355 | 30980 |
Martin J. S. Dyer | 85 | 373 | 24909 |