London Bridge Hospital

About: London Bridge Hospital is a healthcare organization based out in London, United Kingdom. It is known for research contribution in the topics: Antiphospholipid syndrome & Systemic lupus erythematosus. The organization has 107 authors who have published 122 publications receiving 4523 citations.

Cardiovascular effects of testosterone

Abstract: Several studies have evaluated the relationship between cardiovascular disease (CVD) and low testosterone level. Long-term follow-up data suggest that low testosterone level may increase CVD mortality and be a risk factor for CVD development. Low testosterone level is associated with visceral obesity, increased inflammatory markers, insulin resistance, the metabolic syndrome, hyperlipidemia, and impaired endothelial function. Testosterone replacement as a means of modifying CVD risk and reducing CVD morbidity and mortality is an attractive concept; however, evidence of benefit is not yet available. With the particularly strong association between the potential beneficial impact of testosterone therapy and obesity, the metabolic syndrome, and CVD, clinical end-point studies are clearly needed to elucidate the role of testosterone replacement in CVD prevention.

30-Day postoperative COVID-19 outcomes in 398 patients from regional hospitals utilising a designated COVID-19 minimal surgical site pathway.

Abstract: Introduction Postoperative pulmonary complications and mortality rates during the COVID-19 pandemic have been higher than expected, leading to mass cancellation of elective operating in the UK. To ...

PCA3 and Other Urinary Markers

Abstract: With worldwide increasing diagnosis of localised prostate cancer, primarily due to the sensitive but nonspecific PSA test, urologists have dedicated huge resources to identifying urinary biomarkers for prostate cancer diagnosis. Due to the intimate relationship between the prostate and the evacuation of urine through it, a urinary marker is far more appealing than a serum biomarker. Markers would be easy to collect and may not require an invasive procedure if present in sufficient quantities in the urine naturally. Over the last decade, a range of potential urinary markers have been proposed for this role, and this chapter examines their current and potential use in clinical practice.

Current opinion on hydroxychloroquine-related retinal toxicity screening: where do we stand now?

Abstract: Here, we review current hydroxychloroquine screening guidelines and controversies regarding specific screening tests and acceptance of the guidelines. Screening tests are described, and their predictive results are analysed, with special emphasis on early changes. Further research is needed to come to a conclusion about the efficacy of the new proposed dose.