Institution
Louisiana State University
Education•Baton Rouge, Louisiana, United States•
About: Louisiana State University is a education organization based out in Baton Rouge, Louisiana, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 40206 authors who have published 76587 publications receiving 2566076 citations. The organization is also known as: LSU & Louisiana State University and Agricultural and Mechanical College.
Topics: Population, Poison control, Wetland, Autism, Sediment
Papers published on a yearly basis
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University of Tokyo1, Boston University2, Brookhaven National Laboratory3, University of California, Irvine4, California State University, Dominguez Hills5, Chonnam National University6, Duke University7, George Mason University8, Gifu University9, Indiana University10, University of Tsukuba11, Okayama University12, Kobe University13, Kyoto University14, Los Alamos National Laboratory15, Louisiana State University16, University of Maryland, College Park17, University of Minnesota18, Miyagi University of Education19, Stony Brook University20, Nagoya University21, Niigata University22, Osaka University23, Seoul National University24, Shizuoka University25, Sungkyunkwan University26, Tohoku University27, Tokai University28, Tokyo Institute of Technology29, University of Warsaw30, University of Washington31
TL;DR: In this article, a combined analysis of fully-contained, partially-contained and upward-going muon atmospheric neutrino data from a 1489 d exposure of the Super-Kamiokande detector is presented.
Abstract: We present a combined analysis of fully-contained, partially-contained and upward-going muon atmospheric neutrino data from a 1489 d exposure of the Super-Kamiokande detector. The data samples span roughly five decades in neutrino energy, from 100 MeV to 10 TeV. A detailed Monte Carlo comparison is described and presented. The data is fit to the Monte Carlo expectation, and is found to be consistent with neutrino oscillations of {nu}{sub {mu}}{r_reversible}{nu}{sub {tau}} with sin{sup 2}2{theta}>0.92 and 1.5x10{sup -3}<{delta}m{sup 2}<3.4x10{sup -3} eV{sup 2} at 90% confidence level.
701 citations
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TL;DR: The complete genomes were sequenced for ten hepatitis B virus (HBV) strains that were most similar to genotype D, although encoding d specificity, and three divergent strains, which should represent a new HBV genotype, for which the designation H is proposed.
Abstract: The complete genomes were sequenced for ten hepatitis B virus (HBV) strains. Two of them, from Spain and Sweden, were most similar to genotype D, although encoding d specificity. Five of them were from Central America and belonged to genotype F. Two strains from Nicaragua and one from Los Angeles, USA, showed divergences of 3·1–4·1% within the small S gene from genotype F strains and were recognized previously as a divergent clade within genotype F. The complete genomes of the two genotype D strains were found to differ from published genotype D strains by 2·8–4·6%. Their S genes encoded Lys122, Thr127 and Lys160, corresponding to the putative new subtype adw3 within this genotype, previously known to specify ayw2, ayw3 or, rarely, ayw4. The complete genomes of the three divergent strains diverged by 0·8–2·5% from each other, 7·2–10·2% from genotype F strains and 13·2–15·7% from other HBV strains. Since pairwise comparisons of 82 complete HBV genomes of intratypic and intertypic divergences ranged from 0·1 to 7·4% and 6·8 to 17·1%, respectively, the three sequenced strains should represent a new HBV genotype, for which the designation H is proposed. In the polymerase region, the three strains had 16 unique conserved amino acid residues not present in genotype F strains. So far, genotype H has been encountered in Nicaragua, Mexico and California. Phylogenetic analysis of the complete genomes and subgenomes of the three strains showed them clustering with genotype F but forming a separate branch supported by 100% bootstrap. Being most similar to genotype F, known to be an Amerindian genotype, genotype H has most likely split off from genotype F within the New World.
701 citations
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University of Illinois at Urbana–Champaign1, United States Department of Agriculture2, University of California, Los Angeles3, Centre national de la recherche scientifique4, University of Oregon5, Washington University in St. Louis6, Max Planck Society7, VU University Amsterdam8, Cornell University9, University of Cambridge10, Arizona State University11, Louisiana State University12, University of California, Berkeley13, Lawrence Berkeley National Laboratory14, Rothamsted Research15, Georgia Institute of Technology16, ExxonMobil17, Iowa State University18, Australian National University19, University of Düsseldorf20, Texas A&M University21
TL;DR: This work explores an array of prospective redesigns of plant systems at various scales aimed at increasing crop yields through improved photosynthetic efficiency and performance, and suggests some proposed redesigns are certain to face obstacles that will require alternate routes.
Abstract: The world’s crop productivity is stagnating whereas population growth, rising affluence, and mandates for biofuels put increasing demands on agriculture. Meanwhile, demand for increasing cropland competes with equally crucial global sustainability and environmental protection needs. Addressing this looming agricultural crisis will be one of our greatest scientific challenges in the coming decades, and success will require substantial improvements at many levels. We assert that increasing the efficiency and productivity of photosynthesis in crop plants will be essential if this grand challenge is to be met. Here, we explore an array of prospective redesigns of plant systems at various scales, all aimed at increasing crop yields through improved photosynthetic efficiency and performance. Prospects range from straightforward alterations, already supported by preliminary evidence of feasibility, to substantial redesigns that are currently only conceptual, but that may be enabled by new developments in synthetic biology. Although some proposed redesigns are certain to face obstacles that will require alternate routes, the efforts should lead to new discoveries and technical advances with important impacts on the global problem of crop productivity and bioenergy production.
700 citations
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TL;DR: It is suggested that IRS- 1 is a novel direct substrate for IKK and that phosphorylation of IRS-1 at Ser312 (and other sites) by IKK may contribute to the insulin resistance mediated by activation of inflammatory pathways.
697 citations
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TL;DR: A complete understanding of the function of NOX is important to direct the role of this enzyme towards host defense and tissue repair or increase resistance to stress in a timely and disease-specific manner.
Abstract: Oxygen-derived free radicals, collectively termed reactive oxygen species (ROS), play important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are lethal to cells, and the overproduction of these molecules leads to a myriad of devastating diseases. The key producers of ROS in many cells are the NOX family of NADPH oxidases, of which there are seven members, with various tissue distributions and activation mechanisms. NADPH oxidase is a multisubunit enzyme comprising membrane and cytosolic components, which actively communicate during the host responses to a wide variety of stimuli, including viral and bacterial infections. This enzymatic complex has been implicated in many functions ranging from host defense to cellular signaling and the regulation of gene expression. NOX deficiency might lead to immunosuppression, while the intracellular accumulation of ROS results in the inhibition of viral propagation and apoptosis. However, excess ROS production causes cellular stress, leading to various lethal diseases, including autoimmune diseases and cancer. During the later stages of injury, NOX promotes tissue repair through the induction of angiogenesis and cell proliferation. Therefore, a complete understanding of the function of NOX is important to direct the role of this enzyme towards host defense and tissue repair or increase resistance to stress in a timely and disease-specific manner.
692 citations
Authors
Showing all 40485 results
Name | H-index | Papers | Citations |
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H. S. Chen | 179 | 2401 | 178529 |
John A. Rogers | 177 | 1341 | 127390 |
Omar M. Yaghi | 165 | 459 | 163918 |
Barry M. Popkin | 157 | 751 | 90453 |
John E. Morley | 154 | 1377 | 97021 |
Claude Bouchard | 153 | 1076 | 115307 |
Ruth J. F. Loos | 142 | 647 | 92485 |
Ali Khademhosseini | 140 | 887 | 76430 |
Shanhui Fan | 139 | 1292 | 82487 |
Joseph E. LeDoux | 139 | 478 | 91500 |
Christopher T. Walsh | 139 | 819 | 74314 |
Kenneth A. Dodge | 138 | 468 | 79640 |
Steven B. Heymsfield | 132 | 679 | 77220 |
George A. Bray | 131 | 896 | 100975 |
Zhanhu Guo | 128 | 886 | 53378 |