Institution
Lund University
Education•Lund, Sweden•
About: Lund University is a education organization based out in Lund, Sweden. It is known for research contribution in the topics: Population & Cancer. The organization has 42345 authors who have published 124676 publications receiving 5016438 citations. The organization is also known as: Lunds Universitet & University of Lund.
Topics: Population, Cancer, Insulin, Breast cancer, Diabetes mellitus
Papers published on a yearly basis
Papers
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University of Helsinki1, University of Eastern Finland2, Finnish Meteorological Institute3, University of Antwerp4, Weizmann Institute of Science5, University of Bayreuth6, Seconda Università degli Studi di Napoli7, Woods Hole Research Center8, University of Kiel9, Max Planck Society10, Lund University11
TL;DR: In this article, the effect of soil moisture on chamber measurements was tested by wetting the fine quartz sand to about 25% volumetric water content, and the results showed that the chamber headspace concentration also affects the flux by altering the concentration gradient between the soil and the chamber.
489 citations
TL;DR: It is shown here that macrophage-derived gelatinase (matrix metalloproteinase [MMP]-2 and MMP-9) activity is crucial for leukocytes penetration of the parenchymal BM, the first description of selective in situ proteolytic damage of a BBB-specific molecule at sites of leukocyte infiltration.
Abstract: The endothelial cell monolayer of cerebral vessels and its basement membrane (BM) are ensheathed by the astrocyte endfeet, the leptomeningeal cells, and their associated parenchymal BM, all of which contribute to establishment of the blood–brain barrier (BBB). As a consequence of this unique structure, leukocyte penetration of cerebral vessels is a multistep event. In mouse experimental autoimmune encephalomyelitis (EAE), a widely used central nervous system inflammatory model, leukocytes first penetrate the endothelial cell monolayer and underlying BM using integrin β1-mediated processes, but mechanisms used to penetrate the second barrier defined by the parenchymal BM and glia limitans remain uninvestigated. We show here that macrophage-derived gelatinase (matrix metalloproteinase [MMP]-2 and MMP-9) activity is crucial for leukocyte penetration of the parenchymal BM. Dystroglycan, a transmembrane receptor that anchors astrocyte endfeet to the parenchymal BM via high affinity interactions with laminins 1 and 2, perlecan and agrin, is identified as a specific substrate of MMP-2 and MMP-9. Ablation of both MMP-2 and MMP-9 in double knockout mice confers resistance to EAE by inhibiting dystroglycan cleavage and preventing leukocyte infiltration. This is the first description of selective in situ proteolytic damage of a BBB-specific molecule at sites of leukocyte infiltration.
488 citations
TL;DR: This paper presents a short overview of the changes to the trigger and data acquisition systems during the first long shutdown of the LHC and shows the performance of the trigger system and its components based on the 2015 proton–proton collision data.
Abstract: During 2015 the ATLAS experiment recorded 3.8 fb(-1) of proton-proton collision data at a centre-of-mass energy of 13 TeV. The ATLAS trigger system is a crucial component of the experiment, respons ...
488 citations
TL;DR: This work presents a web-based customizable bioinformatics solution called BioArray Software Environment (BASE) for the management and analysis of all areas of microarray experimentation.
Abstract: The microarray technique requires the organization and analysis of vast amounts of data These data include information about the samples hybridized, the hybridization images and their extracted data matrices, and information about the physical array, the features and reporter molecules We present a web-based customizable bioinformatics solution called BioArray Software Environment (BASE) for the management and analysis of all areas of microarray experimentation All software necessary to run a local server is freely available
488 citations
ETH Zurich1, Center for Integrated Protein Science Munich2, University of California, Berkeley3, University of Maryland, College Park4, Université du Québec à Montréal5, University of Louisville6, Université libre de Bruxelles7, University of Maryland, Baltimore County8, Lund University9, The Feinstein Institute for Medical Research10, Wesleyan University11, Yale University12, University of California, Santa Cruz13, McMaster University14, Laboratory of Molecular Biology15, Charité16, Maria Curie-Skłodowska University17, University of Edinburgh18, Scripps Research Institute19, Ludwig Maximilian University of Munich20, Weizmann Institute of Science21
TL;DR: A system for naming ribosomal proteins is described, designed so that new names are similar enough to old names to be easily recognized, but are written in a format that unambiguously identifies them as 'new system' names.
487 citations
Authors
Showing all 42777 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Yi Chen | 217 | 4342 | 293080 |
| Fred H. Gage | 216 | 967 | 185732 |
| Kari Stefansson | 206 | 794 | 174819 |
| Mark I. McCarthy | 200 | 1028 | 187898 |
| Ruedi Aebersold | 182 | 879 | 141881 |
| Jie Zhang | 178 | 4857 | 221720 |
| Feng Zhang | 172 | 1278 | 181865 |
| Martin G. Larson | 171 | 620 | 117708 |
| Michael Snyder | 169 | 840 | 130225 |
| Unnur Thorsteinsdottir | 167 | 444 | 121009 |
| Anders Björklund | 165 | 769 | 84268 |
| Carl W. Cotman | 165 | 809 | 105323 |
| Dennis R. Burton | 164 | 683 | 90959 |
| Jaakko Kaprio | 163 | 1532 | 126320 |
| Panos Deloukas | 162 | 410 | 154018 |