Institution
Lund University
Education•Lund, Sweden•
About: Lund University is a education organization based out in Lund, Sweden. It is known for research contribution in the topics: Population & Cancer. The organization has 42345 authors who have published 124676 publications receiving 5016438 citations. The organization is also known as: Lunds Universitet & University of Lund.
Topics: Population, Cancer, Breast cancer, Insulin, Transplantation
Papers published on a yearly basis
Papers
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TL;DR: Diagnostic criteria for Menière's disease jointly formulated by the Classification Committee of the Bárány Society, The Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology and EAONO and the Equilibrium Committee are presented.
Abstract: This paper presents diagnostic criteria for Meniere's disease jointly formulated by the Classification Committee of the Barany Society, The Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the Equilibrium Committee of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society. The classification includes two categories: definite Meniere's disease and probable Meniere's disease. The diagnosis of definite Meniere's disease is based on clinical criteria and requires the observation of an episodic vertigo syndrome associated with low- to medium-frequency sensorineural hearing loss and fluctuating aural symptoms (hearing, tinnitus and/or fullness) in the affected ear. Duration of vertigo episodes is limited to a period between 20 minutes and 12 hours. Probable Meniere's disease is a broader concept defined by episodic vestibular symptoms (vertigo or dizziness) associated with fluctuating aural symptoms occurring in a period from 20 minutes to 24 hours.
867 citations
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Christian Fuchsberger1, Christian Fuchsberger2, Jason Flannick3, Jason Flannick4 +346 more•Institutions (77)
TL;DR: In this paper, the authors performed whole-genome sequencing in 2,657 European individuals with and without diabetes, and exome sequencing for 12,940 individuals from five ancestry groups.
Abstract: The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association studies have identified scores of common variants associated with type 2 diabetes, but in aggregate, these explain only a fraction of the heritability of this disease. Here, to test the hypothesis that lower-frequency variants explain much of the remainder, the GoT2D and T2D-GENES consortia performed whole-genome sequencing in 2,657 European individuals with and without diabetes, and exome sequencing in 12,940 individuals from five ancestry groups. To increase statistical power, we expanded the sample size via genotyping and imputation in a further 111,548 subjects. Variants associated with type 2 diabetes after sequencing were overwhelmingly common and most fell within regions previously identified by genome-wide association studies. Comprehensive enumeration of sequence variation is necessary to identify functional alleles that provide important clues to disease pathophysiology, but large-scale sequencing does not support the idea that lower-frequency variants have a major role in predisposition to type 2 diabetes.
866 citations
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TL;DR: Arachidonic acid was preferentially incorporated into liver phospholipids as might be expected from the preponderance of this fatty acid in liverospholipid as compared to glycerides and the pattern of label in the blood glyceride closely resembled that in the corresponding liver fraction.
Abstract: Goransson, G. The metabolism of fatty acids in the rat. VI. Arachidonic acid. Acta physiol. scand. 1965. 64. 1–5. -H3-labeled arachidonic acid and C14-labeled palmitic acid were simultaneously injected into male rats. Arachidonic acid was preferentially incorporated into liver phospholipids as might be expected from the preponderance of this fatty acid in liver phospholipids as compared to glycerides. Initially, the labeled arachidonic acid and the labeled palmitic acid were oxidized at similar rates but at later times more arachidonic acid than palmitic acid was recovered from the whole animal. This may be explained by the preferential incorporation of arachidonic acid into phospholipid in combination with the low turnover rate of the phospholipids, especially those containing essential fatty acids. The pattern of label in the blood glycerides closely resembled that in the corresponding liver fraction.
862 citations
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TL;DR: In this paper, the search for a piecewise quadratic Lyapunov function is formulated as a convex optimization problem in terms of linear matrix inequalities, and the relation to frequency domain methods such as the circle and Popov criteria is explained.
Abstract: This paper presents a computational approach to stability analysis of nonlinear and hybrid systems. The search for a piecewise quadratic Lyapunov function is formulated as a convex optimization problem in terms of linear matrix inequalities. The relation to frequency domain methods such as the circle and Popov criteria is explained. Several examples are included to demonstrate the flexibility and power of the approach.
862 citations
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TL;DR: In this article, a shifted zeroth-order Hamiltonian is presented, which will be used in second-order multiconfigurational perturbation theory (CASPT2).
860 citations
Authors
Showing all 42777 results
Name | H-index | Papers | Citations |
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Yi Chen | 217 | 4342 | 293080 |
Fred H. Gage | 216 | 967 | 185732 |
Kari Stefansson | 206 | 794 | 174819 |
Mark I. McCarthy | 200 | 1028 | 187898 |
Ruedi Aebersold | 182 | 879 | 141881 |
Jie Zhang | 178 | 4857 | 221720 |
Feng Zhang | 172 | 1278 | 181865 |
Martin G. Larson | 171 | 620 | 117708 |
Michael Snyder | 169 | 840 | 130225 |
Unnur Thorsteinsdottir | 167 | 444 | 121009 |
Anders Björklund | 165 | 769 | 84268 |
Carl W. Cotman | 165 | 809 | 105323 |
Dennis R. Burton | 164 | 683 | 90959 |
Jaakko Kaprio | 163 | 1532 | 126320 |
Panos Deloukas | 162 | 410 | 154018 |