Institution
Maastricht University
Education•Maastricht, Limburg, Netherlands•
About: Maastricht University is a education organization based out in Maastricht, Limburg, Netherlands. It is known for research contribution in the topics: Population & Health care. The organization has 19263 authors who have published 53291 publications receiving 2266866 citations. The organization is also known as: Universiteit Maastricht & UM.
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TL;DR: The data suggest that high potency marijuana consistently impairs executive function and motor control and use of higher doses of THC in controlled studies may offer a reliable indication of THC induced impairment as compared to lower doses that have traditionally been used in performance studies.
349 citations
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TL;DR: This article summarizes the discussion of the dedicated Task Force during the first Conference of Consensus on Arterial Stiffness held in June 2000 (Paris, France) and analyses methods and devices used worldwide to evaluate the arterial stiffness.
349 citations
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Leiden University Medical Center1, University of Barcelona2, Erasmus University Rotterdam3, University of Valencia4, Karolinska University Hospital5, Maastricht University6, The Royal Marsden NHS Foundation Trust7, Katholieke Universiteit Leuven8, Autonomous University of Barcelona9, Uppsala University10, Aarhus University Hospital11, Radboud University Nijmegen12, Salisbury University13, Catholic University of the Sacred Heart14, Otto-von-Guericke University Magdeburg15, Sahlgrenska University Hospital16, University of Navarra17, Uppsala University Hospital18, Yorkshire Cancer Research19, Martin Luther University of Halle-Wittenberg20, West Middlesex University Hospital21, Esso22, University Medical Center Groningen23, University of Perugia24
TL;DR: The first multidisciplinary consensus conference about cancer of the colon and rectum was held in December 2012 as mentioned in this paper, where the expert panel consisted of representatives of European scientific organisations involved in cancer care of patients with colon and Rectal cancer and representatives of national colorectal registries.
348 citations
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TL;DR: It is suggested that automatic approach tendencies in response to appetitive stimuli could play a role in the etiology of addictive behaviors and related disorders.
Abstract: This study investigated whether automatic approach action tendencies for alcohol-related stimuli were associated with variation in the mu-opioid receptor gene (OPRM1), previously related to rewarding effects of alcohol and craving. An adapted approach avoidance task was used, in which participants pulled or pushed a joystick in reaction to the format of a picture shown on the computer screen (e.g. pull landscape pictures and push portrait pictures). Picture size on the screen changed upon joystick movement, so that upon a pull movement picture size increased (creating a sense of approach) and upon a push movement picture size decreased (avoidance). Participants reacted to four categories of pictures: alcohol-related, other appetitive, general positive and general negative. The sample consisted of 84 heavy drinking young men without a g-allele in the A118G (or A355G) single nucleotide polymorphism of the OPRM1 gene and 24 heavy drinking young men with at least one g-allele. Heavy drinking carriers of a g-allele showed relatively strong automatic approach tendencies for alcohol (approach bias). Unexpectedly, they also showed an approach bias for other appetitive stimuli. No approach bias was found for general positive or negative stimuli. These results suggest that automatic approach tendencies in response to appetitive stimuli could play a role in the etiology of addictive behaviors and related disorders. Further research is needed to investigate the specificity of this approach bias and possible gender differences.
348 citations
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TL;DR: Despite the diminishing effectiveness of SCS over time, 95% of patients with an implant would repeat the treatment for the same result, and results similar to those following PT for pain relief and all other measured variables at 5 years posttreatment.
Abstract: Object Chronic complex regional pain syndrome–Type I (CRPS-I) is a painful, disabling disorder for which no treatment with proven effect is available. In the present randomized controlled trial, the authors assessed the effectiveness of spinal cord stimulation (SCS) in reducing pain due to CRPS-I at the 5-year follow-up. Methods The authors performed a randomized trial in a 2:1 ratio in which 36 patients with CRPS-I were allocated to receive SCS and physical therapy (PT) and 18 patients to receive PT alone. Twenty-four patients who received SCS+PT also underwent placement of a permanent spinal cord stimulator after successful test stimulation; the remaining 12 patients did not receive a permanent stimulator. The authors assessed pain intensity, global perceived effect, treatment satisfaction, and health-related quality of life. Patients were examined before randomization, before implantation, and every year until 5 years thereafter. Ten patients were excluded from the final analysis. Results At 5 years po...
348 citations
Authors
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Name | H-index | Papers | Citations |
---|---|---|---|
Edward Giovannucci | 206 | 1671 | 179875 |
Julie E. Buring | 186 | 950 | 132967 |
Aaron R. Folsom | 181 | 1118 | 134044 |
John J.V. McMurray | 178 | 1389 | 184502 |
Alvaro Pascual-Leone | 165 | 969 | 98251 |
Lex M. Bouter | 158 | 767 | 103034 |
David T. Felson | 153 | 861 | 133514 |
Walter Paulus | 149 | 809 | 86252 |
Michael Conlon O'Donovan | 142 | 736 | 118857 |
Randy L. Buckner | 141 | 346 | 110354 |
Philip Scheltens | 140 | 1175 | 107312 |
Anne Tjønneland | 139 | 1345 | 91556 |
Ewout W. Steyerberg | 139 | 1226 | 84896 |
James G. Herman | 138 | 410 | 120628 |
Andrew Steptoe | 137 | 1003 | 73431 |