Macquarie University

About: Macquarie University is a education organization based out in Sydney, New South Wales, Australia. It is known for research contribution in the topics: Population & Context (language use). The organization has 14075 authors who have published 47673 publications receiving 1416184 citations. The organization is also known as: Macquarie uni.

A synoptic view of the distribution and connectivity of the mid-crustal low velocity zone beneath Tibet

Abstract: [1] Based on 1–2 years of continuous observations of seismic ambient noise data obtained at more than 600 stations in and around Tibet, Rayleigh wave phase velocity maps are constructed from 10 s to 60 s period. A 3-D Vsv model of the crust and uppermost mantle is derived from these maps. The 3-D model exhibits significant apparently inter-connected low shear velocity features across most of the Tibetan middle crust at depths between 20 and 40 km. These low velocity zones (LVZs) do not conform to surface faults and, significantly, are most prominent near the periphery of Tibet. The observations support the internal deformation model in which strain is dispersed in the deeper crust into broad ductile shear zones, rather than being localized horizontally near the edges of rigid blocks. The prominent LVZs are coincident with strong mid-crustal radial anisotropy in western and central Tibet and probably result at least partially from anisotropic minerals aligned by deformation, which mitigates the need to invoke partial melt to explain the observations. Irrespective of their cause in partial melt or mineral alignment, mid-crustal LVZs reflect deformation and their amplification near the periphery of Tibet provides new information about the mode of deformation across Tibet.

The Economics of Cultural Policy

Abstract: Cultural policy is changing. Traditionally, cultural policies have been concerned with providing financial support for the arts, for cultural heritage and for institutions such as museums and galleries. In recent years, around the world, interest has grown in the creative industries as a source of innovation and economic dynamism. This book argues that an understanding of the nature of both the economic and the cultural value created by the cultural sector is essential to good policy-making. The book is the first comprehensive account of the application of economic theory and analysis to the broad field of cultural policy. It deals with general principles of policy-making in the cultural arena as seen from an economic point of view, and goes on to examine a range of specific cultural policy areas, including the arts, heritage, the cultural industries, urban development, tourism, education, trade, cultural diversity, economic development, intellectual property and cultural statistics.

Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours.

Abstract: Testicular germ-cell tumours (TGCT) affect 1 in 500 men and are the most common cancer in males aged 15-40 in Western European populations. The incidence of TGCT has risen dramatically over the last century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT (ref. 7) and a family history of the disease. Brothers of men with TGCT have an 8-10-fold risk of developing TGCT (refs 8,9), whereas the relative risk to fathers and sons is fourfold (ref. 9). This familial relative risk is much higher than that for most other types of cancer. We have collected samples from 134 families with two or more cases of TGCT, 87 of which are affected sibpairs. A genome-wide linkage search yielded a heterogeneity lod (hlod) score of 2.01 on chromosome Xq27 using all families compatible with X inheritance. We obtained a hlod score of 4.7 from families with at least one bilateral case, corresponding to a genome-wide significance level of P=0.034. The proportion of families with UDT linked to this locus was 73% compared with 26% of families without UDT (P=0.03). Our results provide evidence for a TGCT susceptibility gene on chromosome Xq27 that may also predispose to UDT.