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Institution

Macquarie University

EducationSydney, New South Wales, Australia
About: Macquarie University is a education organization based out in Sydney, New South Wales, Australia. It is known for research contribution in the topics: Population & Laser. The organization has 14075 authors who have published 47673 publications receiving 1416184 citations. The organization is also known as: Macquarie uni.
Topics: Population, Laser, Galaxy, Anxiety, Mantle (geology)


Papers
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Journal ArticleDOI
TL;DR: The role of oxidative stress in the pathogenesis of AD, PD, and HD and the protective efficacy of natural products against these diseases are focused and the beneficial effect ofnatural products against neurodegenerative diseases is scientifically validated.
Abstract: Neurodegenerative diseases affect not only the life quality of aging populations, but also their life spans. All forms of neurodegenerative diseases have a massive impact on the elderly. The major threat of these brain diseases includes progressive loss of memory, Alzheimer’s disease (AD), impairments in the movement, Parkinson’s disease (PD), and the inability to walk, talk, and think, Huntington’s disease (HD). Oxidative stress and mitochondrial dysfunction are highlighted as a central feature of brain degenerative diseases. Oxidative stress, a condition that occurs due to imbalance in oxidant and antioxidant status, has been known to play a vital role in the pathophysiology of neurodegenerative diseases including AD, PD, and HD. A large number of studies have utilized oxidative stress biomarkers to investigate the severity of these neurodegenerative diseases and medications are available, but these only treat the symptoms. In traditional medicine, a large number of medicinal plants have been used to treat the symptoms of these neurodegenerative diseases. Extensive studies scientifically validated the beneficial effect of natural products against neurodegenerative diseases using suitable animal models. This short review focuses the role of oxidative stress in the pathogenesis of AD, PD, and HD and the protective efficacy of natural products against these diseases.

348 citations

Journal ArticleDOI
TL;DR: Five potential mechanisms for generating the observed body-size patterns are discussed: the heat-conservation hypothesis, two hypotheses concerning phylogenetic history, the migration-ability hypothesis, and the starvation-resistance hypothesis.
Abstract: Using published distributions of 65 species from the British Isles and northern Europe, we show that ant assemblages change with latitude in two ways. First, as commonly found for many types of organisms, the number of ant species decreased significantly with increasing latitude. For Ireland and Great Britain, species richness also increased significantly with region area. Second, although rarely demonstrated for ectotherms, the body size of ant species, as measured by worker length, increased significantly with increasing latitude. We found that this body-size pattern existed in the subfamily Formicinae and, to a lesser extent, in the Myrmicinae, which together comprised 95% of the ant species in our study area. There was a trend for formicines to increase in size with latitude faster than myrmicines. We also show that the pattern of increasing body size was due primarily to the ranges of ant species shifting to higher latitudes as their body sizes increased, with larger formicines becoming less represented at southerly latitudes and larger myrmicines becoming more represented at northerly latitudes. We conclude by discussing five potential mechanisms for generating the observed body-size patterns: the heat-conservation hypothesis, two hypotheses concerning phylogenetic history, the migration-ability hypothesis, and the starvation-resistance hypothesis.

348 citations

Journal ArticleDOI
TL;DR: This meta-analysis strongly suggests that epoetin alfa therapy for patients with chronic renal failure provides important clinical and quality-of-life benefits while substantially reducing hospitalizations and transfusions.

347 citations

Journal ArticleDOI
TL;DR: Conservation genetics encompasses genetic management of small populations, resolution of taxonomic uncertainties and management units, and the use of molecular genetic analyses in forensics and to understanding species' biology.

347 citations

Journal ArticleDOI
TL;DR: This work compared the representation of photosynthesis in seven TBMs by examining leaf and canopy level responses of photosynthetic CO2 assimilation to key environmental variables: light, temperature, CO2 concentration, vapor pressure deficit and soil water content.
Abstract: Accurate representation of photosynthesis in terrestrial biosphere models (TBMs) is essential for robust projections of global change. However, current representations vary markedly between TBMs, contributing uncertainty to projections of global carbon fluxes. Here we compared the representation of photosynthesis in seven TBMs by examining leaf and canopy level responses of photosynthetic CO2 assimilation (A) to key environmental variables: light, temperature, CO2 concentration, vapor pressure deficit and soil water content. We identified research areas where limited process knowledge prevents inclusion of physiological phenomena in current TBMs and research areas where data are urgently needed for model parameterization or evaluation. We provide a roadmap for new science needed to improve the representation of photosynthesis in the next generation of terrestrial biosphere and Earth system models.

347 citations


Authors

Showing all 14346 results

NameH-indexPapersCitations
Yang Yang1712644153049
Peter B. Reich159790110377
Nicholas J. Talley158157190197
John R. Hodges14981282709
Thomas J. Smith1401775113919
Andrew G. Clark140823123333
Joss Bland-Hawthorn136111477593
John F. Thompson132142095894
Xin Wang121150364930
William L. Griffin11786261494
Richard Shine115109656544
Ian T. Paulsen11235469460
Jianjun Liu112104071032
Douglas R. MacFarlane11086454236
Richard A. Bryant10976943971
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023110
2022463
20214,106
20204,009
20193,549
20183,119