Showing papers by "Mahidol University published in 1970"
TL;DR: G. spinigerum was the causative agent and the routes of migration and exit are described, and it may be a significant cause of intracranial haemorrhages particularly among younger patients in South-East Asia.
42 citations
TL;DR: The present investigation deals with the isolation of salivary immunoglobulins and the demonstration of agglutinating activity against oral bacteria in the isolated Immunoglobulin fractions.
34 citations
27 citations
TL;DR: Virus was most commonly present in children less than one year of age, the incidence falling progressively with age so that it was unusual to recover cytomegalovirus from children over the age of 4 years.
24 citations
TL;DR: The pattern of antibody responses in these fluids differed from one antigen to another, and responses to inactivated viral vaccine and toxoids were almost exclusively associated with the serum IgG component.
Abstract: The nature of antibody activities associated with purified immunoglobulin fractions of serum, secretions (whole saliva, parotid secretion, and intestinal secretion), and urine of a volunteer after subcutaneous booster injections with rabies virus, poliovirus, diphtheria and tetanus toxoids, and typhoid-paratyphoid-cholera vaccines was investigated. The results showed that the pattern of antibody responses in these fluids differed from one antigen to another. Serum-antibody responses to killed-bacterial vaccine were associated mainly with the immunoglobulin M (IgM) component, slight activities were detected in the IgG, and only traces of activities, if any, were found in the IgA. These antibodies were primarily of the secretory IgA type in whole saliva and parotid secretion. Slight activities were also observed in the urinary IgG fraction. Responses to inactivated viral vaccine and toxoids were almost exclusively associated with the serum IgG component. Some antitoxic activities to diphtheria and tetanus toxins were noted in a low-molecular-weight urinary immunoglobulin component.
17 citations
TL;DR: It was found that 50% of the children in two villages in NE were probably deficient in riboflavin, and amongst rural children the test indicated that rib oflavin deficiency was more common in those children over the age of two years.
Abstract: In this study, use has been made of the red cell enzyme glutathione reductase to measure riboflavin status in Thai preschool children (1–7 years). It was found that 50% of the children in two villages in NE. Thailand were probably deficient in riboflavin. In contrast of 72 children examined in a Bangkok orphanage, only two gave results that indicated ariboflavinosis. Amongst rural children the test indicated that riboflavin deficiency was more common in those children over the age of two years.
15 citations
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TL;DR: A new pregnancy test determines the human chorionic gonadotrophin (HCG) level in urine by the inhibition of the reaction between HCG-coated sheep red cells and anti-HCG serum, which is reproducible fast and economical.
Abstract: A new pregnancy test determines the human chorionic gonadotrophin (HCG) level in urine by the inhibition of the reaction between HCG-coated sheep red cells and anti-HCG serum. Glutaraldehyde is used as a coupling agent to coat the sheep red cells with HCG. Sensitivity of hemagglutination inhibition by HCG solutions is used to standardized reagents. Anti-HCG serum is obtained by injecting HCG into the foot pads of a rabbit at 2-week intervals. Serum from blood collected 2 weeks after the third injection is used. Diluted anti-HCG serum is tested against serial dilutions of urine to determine hemagglutinin inhibition. Suitable controls are included in the test. A microtiter system is used. Positive hemagglutination is shown by a mat of cells on the slide. Negative tests show only a small button of cells. The method can be set to detect as little as .25 IU of HCG per ml in a urine specimen but a cross-reaction with luteotropic hormone at low levels of HCG may result in false positive reactions. Therefore the test is usually set to detect 1 IU HCG per ml. Comparable results have been obtained to those achieved with an expensive commercially available kit (Pregnosticon). Tests are reproducible fast and economical. The method may be used to assist in the detection of abnormal pregnancies.
2 citations