Institution
Mahidol University
Education•Bangkok, Nakhon Pathom, Thailand•
About: Mahidol University is a education organization based out in Bangkok, Nakhon Pathom, Thailand. It is known for research contribution in the topics: Population & Malaria. The organization has 23758 authors who have published 39761 publications receiving 878781 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: Antimalarial drug efficacy in uncomplicated malaria should be assessed parasitologically in large, community-based trials, enrolling the age groups most affected by clinical disease, and up to nine weeks could be required to document all recrudescences.
217 citations
TL;DR: Stenting is not mandatory after uncomplicated simple ureteroscopy and shock wave lithotripsy, but there is a subgroup of patients who likely benefit from stenting following a procedure because of the increased risk of complications, including patients at greatest risk for complications.
217 citations
Washington University in St. Louis1, Uppsala University2, University of Pennsylvania3, Intermountain Medical Center4, University of Liverpool5, Marshfield Clinic6, University of Alabama at Birmingham7, Kaiser Permanente8, Mahidol University9, Hospital for Special Surgery10, Uppsala University Hospital11, Karolinska Institutet12, St. Louis College of Pharmacy13, Inje University14, Vanderbilt University15, University of Utah16, Wellcome Trust Sanger Institute17
TL;DR: After several days of therapy, a pharmacogenetic algorithm estimates the therapeutic warfarin dose more accurately than one using clinical factors and INR response alone.
Abstract: Well-characterized genes that affect warfarin metabolism (cytochrome P450 (CYP) 2C9) and sensitivity (vitamin K epoxide reductase complex 1 (VKORC1)) explain one-third of the variability in therapeutic dose before the international normalized ratio (INR) is measured. To determine genotypic relevance after INR becomes available, we derived clinical and pharmacogenetic refinement algorithms on the basis of INR values (on day 4 or 5 of therapy), clinical factors, and genotype. After adjusting for INR, CYP2C9 and VKORC1 genotypes remained significant predictors (P < 0.001) of warfarin dose. The clinical algorithm had an R(2) of 48% (median absolute error (MAE): 7.0 mg/week) and the pharmacogenetic algorithm had an R(2) of 63% (MAE: 5.5 mg/week) in the derivation set (N = 969). In independent validation sets, the R(2) was 26-43% with the clinical algorithm and 42-58% when genotype was added (P = 0.002). After several days of therapy, a pharmacogenetic algorithm estimates the therapeutic warfarin dose more accurately than one using clinical factors and INR response alone.
217 citations
TL;DR: Resistance to artemisinin resistance in Plasmodium falciparum is observed in a patient who was working in Equatorial Guinea.
Abstract: The emergence of artemisinin resistance in Plasmodium falciparum has threatened the effectiveness of malaria treatment in Southeast Asia. In this report, such resistance has been observed in a patient who was working in Equatorial Guinea.
217 citations
University of Texas MD Anderson Cancer Center1, University of Turin2, University of Colorado Denver3, Ohio State University4, Medical University of South Carolina5, Fudan University6, Erasmus University Rotterdam7, Fiona Stanley Hospital8, Princess Margaret Cancer Centre9, Memorial Sloan Kettering Cancer Center10, University of Barcelona11, Keio University12, University of Antwerp13, University of Toronto14, Emory University15, Icahn School of Medicine at Mount Sinai16, University of Lausanne17, University of California, Irvine18, Mahidol University19, Harvard University20, The Chinese University of Hong Kong21, Stanford University22, Medical University of Vienna23, Paul Sabatier University24, Johns Hopkins University25, Yale University26, Yale Cancer Center27, Fred Hutchinson Cancer Research Center28, University of California, Davis29, New York University30
TL;DR: The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of Lung cancer during the past year.
217 citations
Authors
Showing all 23819 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Nicholas J. White | 161 | 1352 | 104539 |
| Pete Smith | 156 | 2464 | 138819 |
| Randal J. Kaufman | 140 | 491 | 79527 |
| Kevin Marsh | 128 | 567 | 55356 |
| Barry M. Trost | 124 | 1635 | 79501 |
| John R. Perfect | 119 | 573 | 52325 |
| Jon Clardy | 116 | 983 | 56617 |
| François Nosten | 114 | 777 | 50823 |
| Paul Turner | 114 | 1099 | 61390 |
| Paul Kubes | 109 | 393 | 41022 |
| Ian M. Adcock | 107 | 660 | 42380 |
| Peter H. Verburg | 107 | 464 | 34254 |
| Guozhong Cao | 104 | 694 | 41625 |
| Carol L. Shields | 102 | 1424 | 46800 |
| Nicholas P. J. Day | 102 | 708 | 50588 |