Institution
Makerere University
Education•Kampala, Uganda•
About: Makerere University is a education organization based out in Kampala, Uganda. It is known for research contribution in the topics: Population & Acquired immunodeficiency syndrome (AIDS). The organization has 7220 authors who have published 12405 publications receiving 366520 citations. The organization is also known as: Makerere University Kampala & MUK.
Papers published on a yearly basis
Papers
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TL;DR: A risk prediction model, the Pre-eclampsia Integrated Estimate of RiSk (miniPIERS) is used to help inform the clinical assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings.
Abstract: Please cite as follows: Payne, B. A. 2014. A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (pre-eclampsia integrated estimate of risk) multi-country prospective cohort study. PLoS Medicine, 11(1):e1001589, doi:10.1371/journal.pmed.1001589.
156 citations
TL;DR: The Commission was prompted by sub-Saharan Africa’s potential to improve health on its own terms, and largely with its own resources, and was one of evidence-based optimism, with caution.
156 citations
TL;DR: In this paper, a study was done to establish medicinal plants used in the treatment of various diseases by the people in the Northern sector of Kibale National Park in western Uganda.
155 citations
Harvard University1, Kathmandu2, The Fred Hollows Foundation3, Makerere University4, National University of Benin5, Partners In Health6, National Institute for Medical Research7, Stellenbosch University8, University of the East9, Saint Francis University10, Centers for Disease Control and Prevention11, Boston University12, University of Göttingen13, University of the Witwatersrand14, University of Birmingham15, Heidelberg University16, Public Health Foundation of India17
TL;DR: Health system performance for management of diabetes showed large losses to care at the stage of being tested, and low rates of diabetes control along the care cascade, indicating large unmet need for diabetes care across 28 LMICs.
Abstract: CITATION: Manne-Goehler, J., et al. 2019. Health system performance for people with diabetes in 28 low- and middle-income countries : a cross-sectional study of nationally representative surveys. PLoS Medicine, 16(3):e1002751, doi:10.1371/journal.pmed.1002751.
155 citations
TL;DR: A cohort of Ugandan individuals who were household contacts of patients with TB are reported, revealing a distinctive adaptive immune profile among Mtb-exposed subjects, supporting an expanded definition of the host response to Mtb exposure, with implications for public health and the design of clinical trials.
Abstract: Exposure to Mycobacterium tuberculosis (Mtb) results in heterogeneous clinical outcomes including primary progressive tuberculosis and latent Mtb infection (LTBI). Mtb infection is identified using the tuberculin skin test and interferon-γ (IFN-γ) release assay IGRA, and a positive result may prompt chemoprophylaxis to prevent progression to tuberculosis. In the present study, we report on a cohort of Ugandan individuals who were household contacts of patients with TB. These individuals were highly exposed to Mtb but tested negative by IFN-γ release assay and tuberculin skin test, ‘resisting’ development of classic LTBI. We show that ‘resisters’ possess IgM, class-switched IgG antibody responses and non-IFN-γ T cell responses to the Mtb-specific proteins ESAT6 and CFP10, immunologic evidence of exposure to Mtb. Compared to subjects with classic LTBI, ‘resisters’ display enhanced antibody avidity and distinct Mtb-specific IgG Fc profiles. These data reveal a distinctive adaptive immune profile among Mtb-exposed subjects, supporting an expanded definition of the host response to Mtb exposure, with implications for public health and the design of clinical trials. New immune biomarkers of exposure to tuberculosis may require a rethink of evidence of Mycobacterium tuberculosis infection and control.
155 citations
Authors
Showing all 7286 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Pete Smith | 156 | 2464 | 138819 |
| Joy E Lawn | 108 | 330 | 55168 |
| Philip J. Rosenthal | 104 | 824 | 39175 |
| William M. Lee | 101 | 464 | 46052 |
| David R. Bangsberg | 97 | 463 | 39251 |
| Daniel O. Stram | 95 | 445 | 35983 |
| Richard W. Wrangham | 93 | 288 | 29564 |
| Colin A. Chapman | 92 | 491 | 28217 |
| Ronald H. Gray | 92 | 529 | 34982 |
| Donald Maxwell Parkin | 87 | 259 | 71469 |
| Larry B. Goldstein | 85 | 434 | 36840 |
| Paul Gepts | 78 | 263 | 19745 |
| Maria J. Wawer | 77 | 357 | 27375 |
| Robert M. Grant | 76 | 437 | 26835 |
| Jerrold J. Ellner | 76 | 347 | 17893 |