Institution
Manhattan Eye, Ear and Throat Hospital
Healthcare•New York, New York, United States•
About: Manhattan Eye, Ear and Throat Hospital is a healthcare organization based out in New York, New York, United States. It is known for research contribution in the topics: Fluorescein angiography & Macular degeneration. The organization has 826 authors who have published 1309 publications receiving 56300 citations.
Topics: Fluorescein angiography, Macular degeneration, Choroidal neovascularization, Visual acuity, Optical coherence tomography
Papers published on a yearly basis
Papers
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TL;DR: In this paper, a method to obtain images of the choroid using conventional spectral-domain optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images was described.
1,759 citations
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TL;DR: This macular disorder, which is named idiopathic polypoidal choroidal vasculopathy (IPCV), appears to represent a distinct entity that differs clinically and demograph-ically from age-related macular degeneration (AMD) and other macular diseases associated with subretinal neovascularization.
Abstract: Eleven patients, 40 to 71 years old, had a choroidal vasculopathy that led to hemorrhagic and exudative macular degeneration. The patients had peculiar polypoidal, subretinal, vascular lesions associated with serous and hemorrhagic detachments of the retinal pigment epithelium. This macular disorder, which we have named idiopathic polypoidal choroidal vasculopathy (IPCV), appears to represent a distinct entity that differs clinically and demograph-ically from age-related macular degeneration (AMD) and other macular diseases associated with subretinal neovascularization. Recognition of this condition is important because it may have specific risk factors, natural course, and management considerations that differ from those of age-related macular degeneration
741 citations
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TL;DR: The choroid in highly myopic eyes is very thin and undergoes further thinning with increasing age and degree of myopia, and abnormalities of the choroids may play a role in the pathogenesis of myopic degeneration.
735 citations
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TL;DR: Results suggest that COX-2 may be a target for the prevention or treatment of HNSCC.
Abstract: The purpose of this study was to determine whether cyclooxygenase-2 (COX-2) was overexpressed in squamous cell carcinoma of the head and neck (HNSCC). Quantitative reverse transcription-PCR, immunoblotting, and immunohistochemistry were used to assess the expression of COX-2 in head and neck tissue. Mean levels of COX-2 mRNA were increased by nearly 150-fold in HNSCC (n = 24) compared with normal oral mucosa from healthy volunteers (n = 17). Additionally, there was about a 50-fold increase in amounts of COX-2 mRNA in normal-appearing epithelium adjacent to HNSCC (n = 10) compared with normal oral mucosa from healthy volunteers. Immunoblotting demonstrated that COX-2 protein was present in six of six cases of HNSCC but was undetectable in normal oral mucosa from healthy subjects. Immunohistochemical analysis showed that COX-2 was expressed in both HNSCC and adjacent normal-appearing epithelium. Taken together, these results suggest that COX-2 may be a target for the prevention or treatment of HNSCC.
719 citations
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TL;DR: The ideal substance for soft-tissue augmentation still eludes physicians, but fat grafting through a blunt cannula seems to be the safest of all of the fillers used; in the hands of an experienced surgeon, it can provide long-lasting, natural-appearing structural changes.
672 citations
Authors
Showing all 829 results
Name | H-index | Papers | Citations |
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Richard F. Spaide | 98 | 422 | 36946 |
Daniel M. Knowles | 93 | 293 | 36557 |
Lawrence A. Yannuzzi | 87 | 471 | 28732 |
Robert Ritch | 86 | 712 | 29080 |
Evangelos S. Gragoudas | 77 | 362 | 24213 |
Joan W. Miller | 76 | 400 | 22602 |
K. Bailey Freund | 72 | 464 | 17307 |
Gary W. Abrams | 65 | 286 | 13202 |
Frederick A. Jakobiec | 64 | 527 | 14440 |
Alon Harris | 63 | 476 | 13346 |
Jeffrey M. Liebmann | 63 | 428 | 13918 |
Jason S. Slakter | 60 | 170 | 15654 |
Stimson P. Schantz | 58 | 218 | 10906 |
John A. Sorenson | 49 | 97 | 12056 |
Marguerite B. McDonald | 48 | 175 | 6965 |