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Institution

Manipal University

EducationManipal, Karnataka, India
About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Medicine. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.


Papers
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Journal ArticleDOI
TL;DR: The results of Raman spectroscopy studies on tissue from mice subjected to brain irradiation support the hypothesis that various protective factors are released throughout the body when the central nervous system is exposed to radiation.
Abstract: Radiotherapy is routinely employed in the treatment of head and neck cancers. Acute cell death, radiation-activated chemical cascades, and the induction of genes coding for protective factors like cytokines are considered to be the major processes involved in radiation damage and repair. It should be possible to follow these processes by monitoring the biochemical interactions initiated by radiation. We have carried out Raman spectroscopy studies on tissue from mice subjected to brain irradiation to identify the biochemical changes occurring in tissue and brain as a result of radiation injury. These studies show that brain irradiation produces drastic spectral changes even in tissue far removed from the irradiation site. The changes are very similar to those produced by the stress of inoculation and restraint and the administration of an anesthetic drug. While the changes produced by stress or anesthetics last for only a short time (a few hours to 1 or 2 days), radiation-induced changes persist even after 1 week. The spectral changes can be interpreted in terms of the observation of new spectra that are dominated by bands due to proteins. The results thus support the hypothesis that various protective factors are released throughout the body when the central nervous system (CNS) is exposed to radiation.

185 citations

Journal ArticleDOI
TL;DR: The pattern of ADRs reported in a tertiary care teaching hospital in South India is comparable with the results of studies conducted in hospital set up elsewhere, and opportunities for interventions especially for the preventable ADRs to ensure safer drug use are revealed.

184 citations

Proceedings ArticleDOI
01 Sep 2017
TL;DR: This paper provides the design of a chatbot, which provides an efficient and accurate answer for any query based on the dataset of FAQs using Artificial Intelligence Markup Language (AIML) and Latent Semantic Analysis (LSA).
Abstract: Chatbots are programs that mimic human conversation using Artificial Intelligence (AI). It is designed to be the ultimate virtual assistant, entertainment purpose, helping one to complete tasks ranging from answering questions, getting driving directions, turning up the thermostat in smart home, to playing one's favorite tunes etc. Chatbot has become more popular in business groups right now as they can reduce customer service cost and handles multiple users at a time. But yet to accomplish many tasks there is need to make chatbots as efficient as possible. To address this problem, in this paper we provide the design of a chatbot, which provides an efficient and accurate answer for any query based on the dataset of FAQs using Artificial Intelligence Markup Language (AIML) and Latent Semantic Analysis (LSA). Template based and general questions like welcome/ greetings and general questions will be responded using AIML and other service based questions uses LSA to provide responses at any time that will serve user satisfaction. This chatbot can be used by any University to answer FAQs to curious students in an interactive fashion.

182 citations

Journal ArticleDOI
TL;DR: In continuation of the work on synthesis of biheterocycles carrying the biodynamic heterocyclic systems at position 3, a series of new nalidixic acid derivatives having quinazolones moiety were synthesised to achieve enhanced biological activity and wide spectrum of activity.

181 citations

Journal ArticleDOI
TL;DR: First year students were found to be more satisfied with the learning environment at MMMC (as indicated by their higher DREEM score) compared to the clinical batch students and gender wise, there was not much difference in the students' perceptions.
Abstract: Background Learning environment in any medical school is found to be important in determining students' academic success. This study was undertaken to compare the perceptions of first year and clinical phase students regarding the learning environment at Melaka Manipal Medical College (MMMC) (Manipal Campus) and also to identify the gender wise differences in their perceptions.

180 citations


Authors

Showing all 9740 results

NameH-indexPapersCitations
John J.V. McMurray1781389184502
Ashok Kumar1515654164086
Zhanhu Guo12888653378
Vijay P. Singh106169955831
Michael Walsh10296342231
Akhilesh Pandey10052953741
Vivekanand Jha9495885734
Manuel Hidalgo9253841330
Madhukar Pai8952233349
Ravi Kumar8257137722
Vijay V. Kakkar6047017731
G. Münzenberg583369837
Abhishek Sharma524269715
Ramesh R. Bhonde492238397
Chandra P. Sharma4832512100
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023102
2022280
20212,150
20201,821
20191,422
20181,083